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Canadian scientist discusses about how society could better prepare for future pandemics

Aled Edwards is of two minds about medicine's response to COVID-19. On one hand, he notes, we had life-saving vaccines and therapies less than a year after the discovery of SARS-CoV-2. On the other, more than six million, and possibly as many as 18 million people have died, and global access to advances that can prevent and treat severe disease remains highly inequitable.

11 Mar 2022

Further optimization of cysteine-reactive pyrazoline-based covalent inhibitors for the SARS-CoV-2 Mpro

Researchers discovered and optimized cysteine-reactive pyrazoline-based covalent inhibitors for several coronaviruses' Mpro, including SARS-CoV-2.

11 Mar 2022

WVU researchers use machine learning and GIS to predict where COVID-19 testing will be most crucial

The National Institutes of Health has called COVID-19 testing "the key to getting back to normal." Yet testing rates have dropped nationwide, even as the Delta and Omicron variants accelerated the virus' spread.

10 Mar 2022

Molecular signature of microorganisms in stool samples could predict pancreatic cancer risk

Pancreatic cancer is not one of the most frequently diagnosed cancers, but it is one of the most lethal due to its early local extension and metastatic behavior.

9 Mar 2022

Rates of rapid antigen test positivity after day 5 from a positive COVID-19 test

A recent study evaluated the positivity rates of COVID-19 rapid antigen tests in infected individuals.

9 Mar 2022

15 medical societies establish seven guiding principles for perioperative treatment of acute pain

The American Society of Anesthesiologists and 14 leading medical specialty organizations established seven guiding principles to better address the perioperative treatment of acute pain in complex surgical patients.

8 Mar 2022

How will mutations change the SARS-CoV-2 spike protein in the future?

A new Cells review discusses the factors that affect the function of the SARS-CoV-2 S protein and provides theoretical limits of this viral protein.

8 Mar 2022

Diabetes and the mTOR pathway in COVID-19 patients

A new study discusses the possible etiopathogenetic mechanisms associated with diabetes that could enhance the severity of COVID-19.

6 Mar 2022

See it to Believe it: How Medical Imaging Technologies Could Help Reduce Health Risks and Inspire Behavior Change

In this interview, we speak to Dr Gareth Hollands about his latest research that investigated the use of medical imaging to reduce health risks and encourage behavior change.

4 Mar 2022

Visualizing health risks with medical imaging may discourage risk-related behaviors, finds study

They say a picture can convey a thousand words, and researchers have found that using medical imaging technologies that can visualize health may discourage risk-related behaviors more than non-visual information.

4 Mar 2022

Handheld ECG devices could be efficiently deployed in point-of-care screening for atrial fibrillation

Point-of-care screening for atrial fibrillation (A-fib) using a new generation of handheld electrocardiogram (ECG) devices increased the rate of diagnosis in patients 85 and older, but failed to show similar results in those 65 and older, a study by Massachusetts General Hospital has found.

3 Mar 2022

Using oral blood pressure drug to treat Type 1 diabetes shows benefits for at least two years

Use of the drug verapamil to treat Type 1 diabetes continues to show benefits lasting at least two years, researchers report in the journal Nature Communications.

3 Mar 2022

Clinical trial report endorses nitazoxanide as a safe drug for moderately ill COVID-19 patients

Researchers tested the safety and efficacy of 600 mg oral dose of nitazoxanide in mild or moderately ill COVID-19 patients.

3 Mar 2022

Study illustrates the link between e-cigarette use and increased odds of prediabetes

An analysis of data from a large, nationally representative survey of the US population shows that e-cigarette use is associated with increased odds of prediabetes.

3 Mar 2022

Triple drug regimen proven effective against non-structural protein-1 of SARS-CoV-2

Researchers evaluated the synergistic activity of drugs acting against non-structural protein 1 of SARS-CoV-2 to decrease the viral infectivity.

2 Mar 2022

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

A new study describes the efficacy of adenosine receptor agonists in the treatment of SARS-CoV-2 infection.

2 Mar 2022

Some oral bacteria associated with development of high blood pressure in postmenopausal women

Some oral bacteria were associated with the development of hypertension, also known as high blood pressure, in postmenopausal women, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

2 Mar 2022

Phase 2/3 study of oral RHB-107 in non-hospitalized COVID-19 patients shows promising results

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced positive top-line results from the Phase 2 part of the Phase 2/3 study of once-daily oral RHB-107 (upamostat) in non-hospitalized symptomatic COVID-19 patients, predominantly conducted in the U.S. (60/61 patients) as well as South Africa.

1 Mar 2022

Exploring Oxford nanopore technology-based on-site SARS-CoV-2 genome sequencing

In a new study, researchers performed genomic sequencing of SARS-CoV-2-infected samples and aimed to identify the dominant variant, assess the mutation profile, and determine the sample-to-sequence turnover time.

1 Mar 2022

Study finds MK-4482 inhibits replication of multiple SARS-CoV-2 variants of concern in Syrian hamster COVID-19 model

Researchers found that an antiviral drug, was effective against SARS-CoV-2 variants, including the recently emerged Omicron variant, in Syrian hamsters.

1 Mar 2022

Oral News and Research

Canadian scientist discusses about how society could better prepare for future pandemics

Further optimization of cysteine-reactive pyrazoline-based covalent inhibitors for the SARS-CoV-2 Mpro

WVU researchers use machine learning and GIS to predict where COVID-19 testing will be most crucial

Molecular signature of microorganisms in stool samples could predict pancreatic cancer risk

Rates of rapid antigen test positivity after day 5 from a positive COVID-19 test

15 medical societies establish seven guiding principles for perioperative treatment of acute pain

How will mutations change the SARS-CoV-2 spike protein in the future?

Diabetes and the mTOR pathway in COVID-19 patients

See it to Believe it: How Medical Imaging Technologies Could Help Reduce Health Risks and Inspire Behavior Change

Visualizing health risks with medical imaging may discourage risk-related behaviors, finds study

Handheld ECG devices could be efficiently deployed in point-of-care screening for atrial fibrillation

Using oral blood pressure drug to treat Type 1 diabetes shows benefits for at least two years

Clinical trial report endorses nitazoxanide as a safe drug for moderately ill COVID-19 patients

Study illustrates the link between e-cigarette use and increased odds of prediabetes

Triple drug regimen proven effective against non-structural protein-1 of SARS-CoV-2

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

Some oral bacteria associated with development of high blood pressure in postmenopausal women

Phase 2/3 study of oral RHB-107 in non-hospitalized COVID-19 patients shows promising results

Exploring Oxford nanopore technology-based on-site SARS-CoV-2 genome sequencing

Study finds MK-4482 inhibits replication of multiple SARS-CoV-2 variants of concern in Syrian hamster COVID-19 model

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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