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Nanoparticle-based therapy alleviates pulmonary hypertension in mouse model of rare lung disease

The disease is so rare and complex that its acronym is hard to pronounce. But for infants unlucky enough to be born with this lung disease, the outcome is usually fatal.

14 Jun 2021

An analysis links COVID-19 to brain microvascular injury and inflammation

The ongoing COVID-19 pandemic is caused by the severe acute respiratory syndrome-2 (SARS-CoV-2), an RNA virus that belongs to the family Coronaviridae. According to research, coronavirus disease 2019 (COVID-19) patients often suffer from neurological disorders like strokes, lost taste or smell, memory loss, confusion, and delirium.

13 Jun 2021

Advanced AI technique can accurately predict major adverse cardiac events

An advanced artificial intelligence technique known as deep learning can predict major adverse cardiac events more accurately than current standard imaging protocols, according to research presented at the Society of Nuclear Medicine and Molecular Imaging 2021 Annual Meeting.

13 Jun 2021

Researchers devise new way to design clot-prone grafts for dialysis

People with end-stage renal disease often undergo hemodialysis, a life-sustaining blood-filtering treatment.

11 Jun 2021

New gene expression network can help understand mechanism behind continuous stem cell activity in plants

An inter-university research group has succeeded in constructing the gene expression network behind the vascular development process in plants.

11 Jun 2021

Study: cis P-tau is an early marker of vascular dementia, Alzheimer's disease

Researchers remain perplexed as to what causes dementia and how to treat and reverse the cognitive decline seen in patients.

11 Jun 2021

New cell-penetrating peptide may protect against life-threatening microbial inflammation

A cell-penetrating peptide developed by researchers at Vanderbilt University Medical Center can prevent, in an animal model, the often-fatal septic shock that can result from bacterial and viral infections.

9 Jun 2021

Having trouble falling asleep associated with cognitive impairment 14 years later

A study of nearly 2,500 adults found that having trouble falling asleep, as compared to other patterns of insomnia, was the main insomnia symptom that predicted cognitive impairment 14 years later.

9 Jun 2021

Healthy behaviors can prevent dementia, finds study

A new Alzheimer's disease drug will hit the market soon, the first in nearly two decades. But some experts say the evidence for it isn't terribly strong and worry that it may cost a lot.

9 Jun 2021

AI could predict treatment demand for chronic eye diseases

Age-related macular degeneration (AMD) is the most common cause of vision loss in people over 50. Up to 12 percent of those over 80 have the chronic disease.

8 Jun 2021

Vascular preservation therapy eliminates the varicose vein problem

Rather than destroying or removing defective veins, it is possible to repair them by using a sheath. They are thus saved for later use as a bypass.

8 Jun 2021

Researchers uncover new gene mutation responsible for cerebral cavernous malformation

Researchers from the Hong Kong University of Science and Technology and Beijing Tiantan Hospital have recently uncovered a new gene mutation responsible for the non-familial patients of cerebral cavernous malformation (CCM) - a brain vascular disorder which inflicted about 10~30 million people in the world.

8 Jun 2021

Testing placental hormone levels can help identify candidates for pregnancy complications

Women who will develop potentially life-threatening disorders during pregnancy can be identified early when hormone levels in the placenta are tested, a new study has shown.

8 Jun 2021

Immunomodulatory therapies for nephrological autoimmune diseases may help treat severe COVID-19

Various viruses and bacteria have long been known to cause autoimmune diseases where there is such a predisposition. This phenomenon also seems to play a major role in SARS-CoV-2, especially in severe courses.

8 Jun 2021

Wearable sensor shows link between blood pressure and intracranial pressure

Brazilian researchers have simultaneously demonstrated the mechanism linking high blood pressure to elevated intracranial pressure, validated a non-invasive intracranial pressure monitoring method, and proposed a treatment for high blood pressure that does not affect intracranial hypertension.

8 Jun 2021

FDA approves monoclonal antibody aducanumab for treating Alzheimer's patients

Today's FDA approval of the monoclonal antibody Aduhelm (aducanumab) to treat patients with Alzheimer's disease reflects years of significant advances in Alzheimer's research. This is the first new Alzheimer's drug approved in 17 years and the first shown to modify the course of the disease, which FDA believes will lead to slowing of patients' cognitive decline.

8 Jun 2021

Lymphangiogenesis predicts favorable outcomes to immunotherapy

Oncotarget published "Mutually exclusive lymphangiogenesis or perineural infiltration in human skin squamous-cell carcinoma" which reported that although tumor-associated lymphangiogenesis correlates with metastasis and poor prognosis in several cancers, it also supports T cell infiltration into the tumor and predicts favorable outcome to immunotherapy.

8 Jun 2021

Study reveals mechanisms by which SGLT2 inhibitors produce renoprotective effect

SGLT2 inhibitors (gliflozins) were developed as oral antidiabetics. They enhance urinary glucose excretion by inhibiting SGLT-2 (sodium-dependent glucose co-transporter-2) in the renal tubuli.

8 Jun 2021

Researchers uncover molecular mechanism linking Parkinson’s disease with COVID-19

The study findings reveal that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection results in abnormal modification of some lung proteins, which are subsequently transported to the brain via exosomes. In the brain, these modified lung proteins disrupt the normal functioning of proteins that are related to Parkinson’s disease.

7 Jun 2021

COVID-19 symptoms in the feet

In a review paper recently uploaded to the Journal of Clinical Medicine by Jimenez-Cebrian et al. (May 19th, 2021), the clinical manifestations of COVID-19 in feet, in particular, are reviewed, finding that vascular, dermatological, and neurological symptoms have been widely reported.

6 Jun 2021

Vascular News and Research

Nanoparticle-based therapy alleviates pulmonary hypertension in mouse model of rare lung disease

An analysis links COVID-19 to brain microvascular injury and inflammation

Advanced AI technique can accurately predict major adverse cardiac events

Researchers devise new way to design clot-prone grafts for dialysis

New gene expression network can help understand mechanism behind continuous stem cell activity in plants

Study: cis P-tau is an early marker of vascular dementia, Alzheimer's disease

New cell-penetrating peptide may protect against life-threatening microbial inflammation

Having trouble falling asleep associated with cognitive impairment 14 years later

Healthy behaviors can prevent dementia, finds study

AI could predict treatment demand for chronic eye diseases

Vascular preservation therapy eliminates the varicose vein problem

Researchers uncover new gene mutation responsible for cerebral cavernous malformation

Testing placental hormone levels can help identify candidates for pregnancy complications

Immunomodulatory therapies for nephrological autoimmune diseases may help treat severe COVID-19

Wearable sensor shows link between blood pressure and intracranial pressure

FDA approves monoclonal antibody aducanumab for treating Alzheimer's patients

Lymphangiogenesis predicts favorable outcomes to immunotherapy

Study reveals mechanisms by which SGLT2 inhibitors produce renoprotective effect

Researchers uncover molecular mechanism linking Parkinson’s disease with COVID-19

COVID-19 symptoms in the feet

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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