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Age plays key role when it comes to patients' access to most efficient psoriasis treatment

A new study from Umeå University in Sweden shows that age plays a huge role when it comes to patients' access to psoriasis treatment. Researchers who have examined if patients of varying ages have the same access to the most efficient psoriasis treatment, found that an age increase of 30 years resulted in an average 65 per cent reduction in likelihood of obtaining treatment with biologics.

20 Jan 2016

Researchers reconstruct 3D images of protein structures that link heart muscle cells in working groups

Diseased hearts may be thrown out of rhythm by structural differences -- now visible for the first time -- in protein groups that connect heart muscle cells, according to the authors of a study to be published in the journal Nature Communications online Jan. 20.

20 Jan 2016

Adding naturally-occurring protein to flu vaccine may offer protection to babies

According to the World Health Organization, influenza causes serious illness among millions of people each year, resulting in 250,000 to 500,000 deaths. Those most at risk include infants younger than six months, because they cannot be vaccinated against the disease.

20 Jan 2016

IMP, WEHI scientists successfully characterize central regulator of plasma cell function

Plasma cells play a key role in our immune system. Now scientists at the Research Institute of Molecular Pathology (IMP) in Vienna, Austria, and at the Walter and Eliza Hall Institute (WEHI) in Melbourne, Australia, succeeded in characterizing a central regulator of plasma cell function.

20 Jan 2016

New technique may accelerate development of novel vaccines

An interdisciplinary team of Oxford University researchers has devised a new technique to speed up the development of novel vaccines.

20 Jan 2016

Hhex protein could be key target for new therapies to cure leukaemia

Melbourne researchers have showed that they can stop leukaemia in its tracks by targeting a protein that puts the handbrake on cancer cell growth.

20 Jan 2016

WASF3 protein appears to be solid target for reducing cancer metastasis

A protein that is constantly expressed by cancer cells and quiescent in healthy ones appears to be a solid target for reducing cancer's ability to spread, scientists report.

19 Jan 2016

Researchers identify protein that could protect against toxic degeneration of cells in ALS

J. Gavin Daigle, a PhD candidate at the LSU Health New Orleans School of Graduate Studies, is the first author of a paper whose findings reveal another piece of the Amyotrophic Lateral Sclerosis (ALS) puzzle.

19 Jan 2016

Profectus begins Phase 1 clinical study of VesiculoVax-vectored Ebola virus vaccine

Profectus BioSciences, Inc., a clinical-stage vaccine company developing novel vaccines for the prevention and treatment of infectious diseases and the treatment of cancer, announced today the initiation of a Phase 1 clinical study of Profectus' VesiculoVax-vectored Ebola virus vaccine.

19 Jan 2016

RIKEN researchers discover how to reverse abnormal axonal development

Researchers at the RIKEN Brain Science Institute in Japan have discovered how to reverse the abnormal axonal development characteristic of CFEOM3, a congenital disease that affects the muscles that control eye movements.

19 Jan 2016

CRISPR/Cas9 gene editing technique could be controlled using RNA-based drugs

In just the past few years, researchers have found a way to use a naturally occurring bacterial system known as CRISPR/Cas9 to inactivate or correct specific genes in any organism. CRISPR/Cas9 gene editing activity runs continuously, though, leading to risk of additional editing at unwanted sites.

19 Jan 2016

Researchers suggest ways to make TB drugs more efficacious against mutations

Biophysicists have discovered why the bacteria that cause tuberculosis (TB) are naturally somewhat resistant to antibiotics known as fluoroquinolones. Their findings, based on mapping the detailed three-dimensional structure of the drugs interacting with an essential enzyme in the TB germ, also reveal why some TB drugs are more potent than others and suggest how drug developers can make fluoroquinolones more efficacious against mutations that make the lung disease drug resistant.

19 Jan 2016

Researchers identify protein structure linked to pain and heat perception

Touch a hot stove, and your fingers will recoil in pain because your skin carries tiny temperature sensors that detect heat and send a message to your brain saying, "Ouch! That's hot! Let go!"

19 Jan 2016

NIST researchers simulate new method for fast, precise DNA sequencing

Researchers at the National Institute of Standards and Technology (NIST) have simulated a new concept for rapid, accurate gene sequencing by pulling a DNA molecule through a tiny, chemically activated hole in graphene--an ultrathin sheet of carbon atoms--and detecting changes in electrical current.

19 Jan 2016

Specialized oral nutrition supplement associated with 50% lower death rate in older patients

Results from a new clinical trial show that a specialized oral nutrition supplement was associated with a 50 percent lower death rate in older malnourished patients with a heart or lung disease 90 days following hospitalization.

18 Jan 2016

UT Southwestern pediatric researchers identify key trigger of neonatal lung disease

Pediatric researchers at UT Southwestern Medical Center have identified a key component of the pathogenesis of bronchopulmonary dysplasia (BPD), a devastating and sometimes fatal lung disease that affects premature infants. Their findings clarify what prompts the inflammatory response that results in BPD, which previously had been unclear.

18 Jan 2016

Findings offer potential new therapeutic target to boost strength of heart muscle contractions

Researchers at UT Southwestern Medical Center have identified a previously unrecognized small protein in cells of the human heart that plays a key role in heart muscle contraction. The protein is made from an RNA that was previously believed to be a blank or non-coding RNA, suggesting there may be many other small 'non-coding' segments that play important biological roles.

18 Jan 2016

Protein C News and Research

Age plays key role when it comes to patients' access to most efficient psoriasis treatment

Researchers reconstruct 3D images of protein structures that link heart muscle cells in working groups

Adding naturally-occurring protein to flu vaccine may offer protection to babies

IMP, WEHI scientists successfully characterize central regulator of plasma cell function

New technique may accelerate development of novel vaccines

Hhex protein could be key target for new therapies to cure leukaemia

WASF3 protein appears to be solid target for reducing cancer metastasis

Researchers identify protein that could protect against toxic degeneration of cells in ALS

Profectus begins Phase 1 clinical study of VesiculoVax-vectored Ebola virus vaccine

RIKEN researchers discover how to reverse abnormal axonal development

CRISPR/Cas9 gene editing technique could be controlled using RNA-based drugs

Researchers suggest ways to make TB drugs more efficacious against mutations

Researchers identify protein structure linked to pain and heat perception

NIST researchers simulate new method for fast, precise DNA sequencing

Specialized oral nutrition supplement associated with 50% lower death rate in older patients

UT Southwestern pediatric researchers identify key trigger of neonatal lung disease

Findings offer potential new therapeutic target to boost strength of heart muscle contractions

Scientists find new way to re-engineer body’s immune system to target cancer

Eating habits may influence sleep quality

Gene linked to autism lays groundwork for crucial brain structure during prenatal development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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