Genetic News and Research

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Researchers discover new genetic risk factor for schizophrenia, bipolar disorder

Investigators at The Feinstein Institute for Medical Research have discovered a new genetic risk factor for schizophrenia and bipolar disorder called NDST3. The findings are published online in Nature Communications.

20 Nov 2013

Scientists at Salk Institute develop novel platform to study kidney diseases

Diseases affecting the kidneys represent a major and unsolved health issue worldwide. The kidneys rarely recover function once they are damaged by disease, highlighting the urgent need for better knowledge of kidney development and physiology.

19 Nov 2013

Curie-Cancer inks partnership agreements with Meiogenix to develop SpiX technology

Curie-Cancer, the body responsible for developing Institut Curie's industry partnership activity, today announces two three-year partnership agreements with Meiogenix, a French SME. Meiogenix develops SpiX technology under license from Institut Curie and Institut National de la Recherche Agronomique.

19 Nov 2013

Atopix recruits first patient in OC459 Phase 2 trial for treatment of atopic dermatitis

Atopix Therapeutics Ltd, a biopharmaceutical company developing innovative CRTH2 antagonists for allergic disease, announced the recruitment of the first patient in a six month Phase 2 clinical trial of its lead compound OC459 in moderate-to-severe atopic dermatitis (eczema).

19 Nov 2013

Study confirms therapeutic potential of inhibiting Aurora-A in cancer treatment

Aurora-A is a protein involved in the cell division process that is highly expressed or synthesised in a large number of human cancers, especially in those associated with a bad prognosis. Several pharmaceutical companies have recently developed these protein inhibitors, although the therapeutic and physiological effects that blocking Aurora-A might have on adult tissues are still unknown.

19 Nov 2013

Findings may help scientists better understand prognosis of advanced prostate cancer

Many patients diagnosed with prostate cancer have indolent, slow-growing forms of the disease that are not life-threatening. However, more than 30,000 American men will die from aggressive prostate cancer this year alone. This sharp contrast between low-risk and aggressive disease presents a challenge for many researchers and physicians as they diagnose patients and also determine the prognosis of the men with the most aggressive forms of prostate cancer.

19 Nov 2013

Cesarean deliveries do not prevent children from cerebral palsy

Cesarean deliveries do not prevent children from developing cerebral palsy, despite long-held medical and community beliefs about the causes of cerebral palsy, according to new research led by the University of Adelaide.

19 Nov 2013

Manipulating PRH protein can help prevent cancer cells from unnecessary migration

Understanding how and why cancer cells move away from their original location is important to find ways to stop the spread of the disease. New findings, published in the Nature journal Oncogene, reveal how a protein, called 'PRH', is normally able to prevent cells from unnecessary migration. It is likely that this protein is less effective in cancer cells allowing the cells to venture away.

19 Nov 2013

Scientists use new method to draw map of cancer's family tree

A new method to take the DNA fingerprint of individual cancer cells is uncovering the true extent of cancer's genetic diversity, new research reveals.

19 Nov 2013

Gilead Sciences gets marketing authorization from European Commission for Vitekta tablets

Gilead Sciences, Inc. today announced that the European Commission has granted marketing authorization for Vitekta (elvitegravir 85 mg and 150 mg) tablets, an integrase inhibitor for the treatment of HIV-1 infection in adults without known mutations associated with resistance to elvitegravir.

18 Nov 2013

DNA tells the story of how ancient humans first came to the Americas

University of Illinois anthropology professor Ripan Malhi looks to DNA to tell the story of how ancient humans first came to the Americas and what happened to them once they were here.

18 Nov 2013

Oxford scientists use nanoparticles to study mechanisms underlying 'mystery' cases of infertility

A way of using nanoparticles to investigate the mechanisms underlying 'mystery' cases of infertility has been developed by scientists at Oxford University.

18 Nov 2013

Researchers develop novel system to image worm brain activity

A research team at Worcester Polytechnic Institute and The Rockefeller University in New York has developed a novel system to image brain activity in multiple awake and unconstrained worms. The technology, which makes it possible to study the genetics and neural circuitry associated with animal behavior, can also be used as a high-throughput screening tool for drug development targeting autism, anxiety, depression, schizophrenia, and other brain disorders.

18 Nov 2013

Study: New device helps people who lost vision due to blinding genetic disease

Research presented today at the 117th Annual Meeting of the American Academy of Ophthalmology shows promising data about a device that helps people who have lost their vision due to a blinding genetic disease to recognize common objects.

18 Nov 2013

Scientists describe interplay of four molecules that trigger, govern antibody production in immune cells

Australian scientists have described an exquisitely balanced interplay of four molecules that trigger and govern antibody production in immune cells. As well as being an important basic science discovery, it helps explain why people with mutations in any one of the associated genes cannot fight infection effectively, and develop rare and crippling immunodeficiency disorders.

18 Nov 2013

Researchers generate three-dimensional kidney structures from human stem cells

18 Nov 2013

Study suggests potential new treatment for seizures

A study out today in the journal Nature Medicine suggests a potential new treatment for the seizures that often plague children with genetic metabolic disorders and individuals undergoing liver failure. The discovery hinges on a new understanding of the complex molecular chain reaction that occurs when the brain is exposed to too much ammonia.

17 Nov 2013

Genetic mutations in parasite cause over 100 million cases of malaria annually in Africa

Researchers at Case Western Reserve University and Cleveland Clinic Lerner Research Institute have discovered recent genetic mutations in a parasite that causes over 100 million cases of malaria annually-changes that may render tens of millions of Africans who had been considered resistant, susceptible to infection.

16 Nov 2013

E-Rare funding recommended for European young investigators network for Usher syndrome

Based on a ranking list that was established by the EU Scientific Evaluation Committee, the E-Rare funding bodies recommended the European young investigators network for Usher syndrome coordinated by Dr. Kerstin Nagel-Wolfrum from Johannes Gutenberg University Mainz for funding. Out of 82 submitted projects, EUR-USH was among the 11 excellent scientific projects that were chosen after a competitive two-step scientific evaluation by peers. In October 2013, researchers held their kick-off meeting in Nijmegen, the Netherlands.

16 Nov 2013

Research paper highlights experiences, results of celiac disease screening in young children

Most children who undergo screening to detect gluten intolerance, celiac disease, can handle it well. However, many people feel that the discovery of the disease and the treatment they receive does not provide a better quality of life.

16 Nov 2013

Genetic News and Research

Researchers discover new genetic risk factor for schizophrenia, bipolar disorder

Scientists at Salk Institute develop novel platform to study kidney diseases

Curie-Cancer inks partnership agreements with Meiogenix to develop SpiX technology

Atopix recruits first patient in OC459 Phase 2 trial for treatment of atopic dermatitis

Study confirms therapeutic potential of inhibiting Aurora-A in cancer treatment

Findings may help scientists better understand prognosis of advanced prostate cancer

Cesarean deliveries do not prevent children from cerebral palsy

Manipulating PRH protein can help prevent cancer cells from unnecessary migration

Scientists use new method to draw map of cancer's family tree

Gilead Sciences gets marketing authorization from European Commission for Vitekta tablets

DNA tells the story of how ancient humans first came to the Americas

Oxford scientists use nanoparticles to study mechanisms underlying 'mystery' cases of infertility

Researchers develop novel system to image worm brain activity

Study: New device helps people who lost vision due to blinding genetic disease

Scientists describe interplay of four molecules that trigger, govern antibody production in immune cells

Researchers generate three-dimensional kidney structures from human stem cells

Study suggests potential new treatment for seizures

Genetic mutations in parasite cause over 100 million cases of malaria annually in Africa

E-Rare funding recommended for European young investigators network for Usher syndrome

Research paper highlights experiences, results of celiac disease screening in young children

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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