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New computational model simulates the spread and impact of COVID-19 virus

The emergence and rapid spread of novel Covid-19 coronavirus in early 2020 spurred numerous accelerated efforts to develop a vaccine. At the time it was not clear how effective these vaccines needed to be to slow or stop the pandemic.

18 Jun 2021

$Researchers report a new genetic cause for infantile fractures$

Researchers report a new genetic cause for infantile fractures

An intrauterine fracture is a rare finding during routine prenatal imaging. This condition can be due to maternal trauma, genetic disorders of the skeleton, as well as other predisposing maternal metabolic and vascular disorders.

18 Jun 2021

Combination of anti-HER2 breast cancer therapy and checkpoint inhibitor provides no benefit

Adding an immune checkpoint inhibitor to anti-HER2 treatment in breast cancer does not improve pathological complete response (pCR), according to the primary analysis of the IMpassion050 trial presented today during the ESMO Virtual Plenary.

18 Jun 2021

New methods may lead to optimal treatment for lung cancer

Today as they did 100 years ago, doctors diagnose cancer by taking tissue samples from patients, which they usually fix in formalin for microscopic examination.

18 Jun 2021

Adding immune oncology drug to chemotherapy improves response in subset of breast cancer patients

In a new study by researchers at Yale Cancer Center, combining the immunotherapy drug durvalumab and PARP-inhibitor olaparib with chemotherapy improved response to treatment for women with high-risk, HER2-negative breast cancer, including a subset of estrogen receptor positive cancers.

18 Jun 2021

Presence of certain stem cells linked to nongenetic resistance mechanisms of cancer cells

Cancer cells can develop resistance to therapy through both genetic and non-genetic mechanisms. But it is unclear how and why one of these routes to resistance prevails.

18 Jun 2021

Study: Cancer cells grown in culture dishes have less parity with their human sources

In a bid to find or refine laboratory research models for cancer that better compare with what happens in living people, Johns Hopkins Medicine scientists report they have developed a new computer-based technique showing that human cancer cells grown in culture dishes are the least genetically similar to their human sources.

18 Jun 2021

Study finds new clues to explain how Alzheimer’s disease spreads in the brain

Case Western Reserve University researchers studying prions - misfolded proteins that cause lethal incurable diseases - have identified for the first time surface features of human prions responsible for their replication in the brain.

18 Jun 2021

Proven treatment for psychosis has been recognized as standard of care

Most people with a serious mental illness like schizophrenia will not obtain adequate care. Many end up in correctional facilities on medication or become homeless.

18 Jun 2021

New details on transport protein could help develop drugs for neurological diseases

New details on the structure and function of a transport protein could help researchers develop drugs for neurological diseases that are better able to cross the blood-brain barrier.

18 Jun 2021

Ride e-scooters with safety to prevent head and neck injuries

As pandemic restrictions begin to loosen around the country and summer temperatures rise, more people will be moving about on public rideshare electric scooters. With that comes this warning: Ride with safety.

18 Jun 2021

Researchers create the most comprehensive atlas of human transcriptome

Together with Baylor College of Medicine and the world's leading sequencing company, Illumina, researchers at Ghent University have built one of the most comprehensive catalogues of the human transcriptome ever.

18 Jun 2021

Cinnamon compound could be useful supplement to dexamethasone in COVID-19 treatment

Researchers in Germany and the United States have conducted a study showing that supplementing dexamethasone treatment with Ceylon cinnamon in cases of coronavirus disease 2019 (COVID-19) may allow dexamethasone to be administered at lower doses, thereby avoiding the side effects that occur with high doses of the steroid.

17 Jun 2021

Unequal hospital quality associated with higher COVID-19 death rate for Black patients

The COVID-19 death rate for Black patients would be 10 percent lower if they had access to the same hospitals as white patients, a new study shows.

17 Jun 2021

APOE ɛ4 carriers with midlife depressive symptoms may be at higher risk of tau accumulation

Middle-aged people with depressive symptoms who carry a genetic variation called apolipoprotein (APOE) ε4 may be more at risk to develop tau protein accumulations in the brain's emotion- and memory-controlling regions, a new study by researchers from The University of Texas Health Science Center at San Antonio and collaborating institutions suggests.

17 Jun 2021

Inhibiting necroptosis could be a novel approach for treating COPD

Research shows that inhibiting necroptosis, a form of cell death, could be a novel therapeutic approach for treating chronic obstructive pulmonary disease, an inflammatory lung condition, also known as emphysema, that makes it difficult to breathe.

17 Jun 2021

UC Davis Clinical Translational Science Center receives its third NIH award renewal

The UC Davis Clinical Translational Science Center (CTSC) received notice of its third National Institutes of Health (NIH) award renewal, a vote of confidence in the center's ability to advance outstanding research in human health.

17 Jun 2021

Novel drug class shows potential to treat cancer patients with faulty BRCA genes

Scientists have identified a new class of targeted cancer drugs that offer the potential to treat patients whose tumors have faulty copies of the BRCA cancer genes.

17 Jun 2021

Genetically engineering NK cells can destroy tumor-regenerating glioblastoma stem cells

Preclinical research from The University of Texas MD Anderson Cancer Center finds that although glioblastoma stem cells (GSCs) can be targeted by natural killer (NK) cells, they are able to evade immune attack by releasing the TFG-β signaling protein, which blocks NK cell activity.

17 Jun 2021

Neighborhood disadvantage related to increased COVID-19 infections and mortality

New York City neighborhoods that had higher levels of socioeconomic disadvantage experienced more COVID-19 infections and deaths, according to Mount Sinai scientists who created a neighborhood-level COVID-19 inequity index.

17 Jun 2021

Medicine News and Research

New computational model simulates the spread and impact of COVID-19 virus

Researchers report a new genetic cause for infantile fractures

Combination of anti-HER2 breast cancer therapy and checkpoint inhibitor provides no benefit

New methods may lead to optimal treatment for lung cancer

Adding immune oncology drug to chemotherapy improves response in subset of breast cancer patients

Presence of certain stem cells linked to nongenetic resistance mechanisms of cancer cells

Study: Cancer cells grown in culture dishes have less parity with their human sources

Study finds new clues to explain how Alzheimer’s disease spreads in the brain

Proven treatment for psychosis has been recognized as standard of care

New details on transport protein could help develop drugs for neurological diseases

Ride e-scooters with safety to prevent head and neck injuries

Researchers create the most comprehensive atlas of human transcriptome

Cinnamon compound could be useful supplement to dexamethasone in COVID-19 treatment

Unequal hospital quality associated with higher COVID-19 death rate for Black patients

APOE ɛ4 carriers with midlife depressive symptoms may be at higher risk of tau accumulation

Inhibiting necroptosis could be a novel approach for treating COPD

UC Davis Clinical Translational Science Center receives its third NIH award renewal

Novel drug class shows potential to treat cancer patients with faulty BRCA genes

Genetically engineering NK cells can destroy tumor-regenerating glioblastoma stem cells

Neighborhood disadvantage related to increased COVID-19 infections and mortality

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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