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Crystal structures of key fluorescent proteins to "light up" molecules in cells

Scientists at Albert Einstein College of Medicine of Yeshiva University have determined the crystal structures of two key fluorescent proteins - one blue, one red - used to "light up" molecules in cells.

23 Apr 2010

Plant-based vaccine factory to produce vaccines and therapeutics within weeks of outbreaks

The Fraunhofer Center for Molecular Biotechnology in Newark, Delaware, the Fraunhofer Center for Manufacturing Innovation in Boston, Massachusetts, the Boston University College of Engineering, and the biopharmaceutical company iBio, Inc. in Newark, Delaware, announced today that they have developed a fully automated, scalable "factory" that uses natural (non-genetically-modified) green plants to efficiently produce large quantities of vaccines and therapeutics within weeks.

23 Apr 2010

University of Granada scientists create artificial human skin with dermis made of fibrin-agarose biomaterial

Scientists from the University of Granada, Spain, have generated artificial human skin by tissular engineering basing on agarose-fibrin biomaterial. The artificial skin was grafted onto mice, and optimal development, maturation and functionality results were obtained.

23 Apr 2010

UIC College of Dentistry awarded $10M federal grant to upgrade research facilities

The University of Illinois at Chicago College of Dentistry has received a $10 million federal grant to transform its research facilities into a state-of-the-art clinical and translational research center.

23 Apr 2010

PCFT helps in effectively targeting cytotoxic antifolates to tumors: Study

Scientists at the Barbara Ann Karmanos Cancer Institute in Detroit today presented a poster at the American Association for Cancer Research's 101st Annual Meeting 2010 that details their novel study of molecules that use a tumor's acidic microenvironment to help them tailor chemotherapeutic agents to kill the tumor.

23 Apr 2010

Essilorl's first-quarter 2010 consolidated revenues up 7.8%

Essilor International, the world leader in ophthalmic optics, today announced that consolidated revenue for the three months ended March 31, 2010 rose by 7.8% to EUR905.8 million, in line with stated objectives.

23 Apr 2010

Scientists develop new way of modifying viruses to seek out and destroy cancer cells

CANCER RESEARCH UK scientists at the University of Leeds have developed a new way of modifying viruses to seek out and destroy cancer cells, according to research published in Gene Therapy today1 (Friday).

23 Apr 2010

Transposagen Biopharmaceuticals announces new TGEM Rat Model product line

Transposagen Biopharmaceuticals, Inc., based in Lexington, KY, has announced today that it has added 170 genetically modified rats and related biomaterials to its database of laboratory rats with a genetic modification that can mimic a human disease. These animals are used by academic, pharmaceutical, and biotech scientists for drug discovery and development research and will be sold under Transposagen's new TGEM(TM) Rat Models brand.

23 Apr 2010

Researchers to measure children with Down syndrome to develop new growth charts

Parents and doctors have known for a long time that children with Down syndrome tend to grow more slowly and are considerably shorter than most other children. But pediatricians needing to record growth milestones at regular office visits have an outdated set of growth charts based on data collected more than 25 years ago.

23 Apr 2010

Mayo Clinic study finds changes in tissue damage throughout the course of MS

A new Mayo Clinic study has found that the type of tissue damage changes throughout the course of multiple sclerosis. In early relapsing disease stages, the plaques, or areas where the nervous system is inflamed or demyelinated, are predominantly active with distinct heterogeneous patterns of myelin damage.

23 Apr 2010

BUSM professor receives Individual Biomedical Research Award

Richard Goldstein, PhD, a professor of pediatrics, division of pediatric infectious diseases, at Boston University School of Medicine, has been awarded an Individual Biomedical Research Award by The Hartwell Foundation and will receive $300,000 over three years as a Hartwell Investigator for his project titled, "A Vaccine Against Streptococcus Pneumoniae Based on Bacterial Surface Proteins Phylogenically Certified as Highly Conserved."

23 Apr 2010

Celator Pharmaceuticals presents data on CPX-351 Liposome Injection and HDPN formulation

Celator Pharmaceuticals today announced data from animal studies demonstrating the superior bone marrow uptake of CPX-351 (Cytarabine:Daunorubicin) Liposome Injection, its lead clinical-stage program, as well as the enhanced circulation kinetics and efficacy of its preclinical hydrophobic docetaxel prodrug nanoparticle (HDPN) formulation were presented at the 101st Annual Meeting of the American Association for Cancer Research in Washington, DC (Abstracts 3698 and 5534).

23 Apr 2010

Study uses new BL-DMAC method to measure PAC levels in cranberry products

Natural compounds in cranberries are linked to the prevention of urinary tract infections (UTIs) but inconsistencies in methods currently used commercially to measure levels can result in the over- or under-estimation of potency levels, leaving product manufacturers and consumers without good data. A study published today in the Journal of the Science of Food and Agriculture outlines a new, commercially viable method of measuring these compounds.

22 Apr 2010

Human lymphocytes produce hepcidin that regulate iron levels in the body: Study

For some years now a small group of scientists have been pioneering a revolutionary idea - that the vertebrate immune system could have a role in the regulation of iron in the body. And now, a work soon to be published in the journal Immunology, shows that human lymphocytes (white blood cells) actually produce hepcidin, the most important protein in the regulation of iron levels in the body.

22 Apr 2010

Larger sized intravenous anesthetic diazepam incubated in isolation with Aβ peptide does not promote aggregation

Alzheimer's disease (AD) is a neurodegenerative disorder affecting millions of people worldwide and has become a major global concern. Uncontrolled oligomerization (aggregation) of Aβ peptide is the hallmark of AD and it is believed to be causally related to AD pathomechanism.

22 Apr 2010

Understanding genetic causes of mental retardation

This remarkable publication focuses on the importance of genetics in mental retardation, investigating the extent to which molecular diagnostic capability and the understanding of genetic causes have improved over recent years. As a result, clinical evaluation and diagnostic laboratory practice are now undergoing an unprecedented period of change.

22 Apr 2010

Enigma ML instrument system to be showcased at InnovHealth 2010 summit

Enigma Diagnostics Limited, the decentralised and point-of-care molecular diagnostics company, announced today that it will be a product provider at the InnovHealth - Middle East Healthcare Innovations Summit in Abu Dhabi on 25 and 26 April 2010 and will be presenting the Enigma ("Mini Laboratory") instrument system.

22 Apr 2010

DiagnoCure's proprietary prostate cancer biomarker PCA3 presented at 2010 EAU meeting

DiagnoCure, Inc., a life sciences company commercializing high-value cancer diagnostic tests and delivering laboratory services, announced that its proprietary prostate cancer biomarker PCA3 was the topic of over 13 presentations at the 2010 European Association of Urology meeting, the world largest urology event, held in Barcelona, Spain, with 14,000 registrants.

22 Apr 2010

New studies on cancer prevention presented at 101st AACR Annual Meeting 2010

Interest in cancer prevention is increasing as scientists continue to learn new information and confirm what was already suspected.

22 Apr 2010

GUMC researchers awarded grant to discover and develop new smoking cessation drugs

A Georgetown University Medical Center research team has been awarded a grant from the National Institute on Drug Abuse to discover and develop new smoking cessation drugs based on an unconventional theory about nicotine addiction. Kenneth Kellar, PhD, a professor of pharmacology at GUMC is principal investigator of the five year grant totaling $4.6 million.

22 Apr 2010

Laboratory News and Research

Crystal structures of key fluorescent proteins to "light up" molecules in cells

Plant-based vaccine factory to produce vaccines and therapeutics within weeks of outbreaks

University of Granada scientists create artificial human skin with dermis made of fibrin-agarose biomaterial

UIC College of Dentistry awarded $10M federal grant to upgrade research facilities

PCFT helps in effectively targeting cytotoxic antifolates to tumors: Study

Essilorl's first-quarter 2010 consolidated revenues up 7.8%

Scientists develop new way of modifying viruses to seek out and destroy cancer cells

Transposagen Biopharmaceuticals announces new TGEM Rat Model product line

Researchers to measure children with Down syndrome to develop new growth charts

Mayo Clinic study finds changes in tissue damage throughout the course of MS

BUSM professor receives Individual Biomedical Research Award

Celator Pharmaceuticals presents data on CPX-351 Liposome Injection and HDPN formulation

Study uses new BL-DMAC method to measure PAC levels in cranberry products

Human lymphocytes produce hepcidin that regulate iron levels in the body: Study

Larger sized intravenous anesthetic diazepam incubated in isolation with Aβ peptide does not promote aggregation

Understanding genetic causes of mental retardation

Enigma ML instrument system to be showcased at InnovHealth 2010 summit

DiagnoCure's proprietary prostate cancer biomarker PCA3 presented at 2010 EAU meeting

New studies on cancer prevention presented at 101st AACR Annual Meeting 2010

GUMC researchers awarded grant to discover and develop new smoking cessation drugs

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