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Alkaloids show potential as treatments for COVID-19

To further study these organic compounds, researchers from Kermanshah University of Medical Sciences, Iran, and Universidad de Santiago de Chile, Chile, reviewed the role of alkaloids as a potential antiviral, specifically against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). They presented the chemistry, plant sources, and antiviral effects of alkaloids and their anti-SARS-CoV-2 effect.

15 Jun 2021

Treatment-resistant depression relieved by laughing gas

Researchers at the Washington University School of Medicine in St. Louis and the University of Chicago have found that a single, one-hour treatment involving the inhalation of a mixture of oxygen and the anesthetic drug nitrous oxide, also known as laughing gas, can improve symptoms of depression in people resistant to treatment.

15 Jun 2021

Weight-based dosing strategy may affect immunotherapy outcomes, shows study

Overweight cancer patients receiving immunotherapy treatments live more than twice as long as lighter patients, but only when dosing is weight-based, according to a study by cancer researchers at UT Southwestern Medical Center.

15 Jun 2021

Study uncovers novel drug that effectively thwarts pancreatic tumors

Pancreatic cancer is an aggressive disease in which malignant cells form in the tissues of the pancreas, a long and flat gland located behind the stomach that helps with digestion and blood sugar regulation.

14 Jun 2021

Study reveals risk factors associated with COVID-19 outcomes for people with IDD

A study of nearly 550 adults with intellectual and developmental disabilities receiving residential services in New York City found that age, larger residential settings, Down syndrome and chronic kidney disease were the most common risk factors for COVID-19 diagnosis, and heart disease was most associated with COVID-19 deaths.

14 Jun 2021

Researchers study sick-leave patterns after Covid-19

Nearly 12,000 people in Sweden received sickness benefit from the Swedish Social Insurance Agency for COVID-19 during the first wave of the pandemic.

14 Jun 2021

Stents inspired by kirigami could deliver drugs to tubular organs

Inspired by kirigami, the Japanese art of folding and cutting paper to create three-dimensional structures, MIT engineers and their collaborators have designed a new type of stent that could be used to deliver drugs to the gastrointestinal tract, respiratory tract, or other tubular organs in the body.

14 Jun 2021

COVID-19 public health efforts linked to dramatic decline in COPD hospitalizations

Researchers at the University of Maryland School of Medicine analyzed data at the 13-hospital University of Maryland Medical System and found public health measures designed to reduce the spread of the COVID-19 virus may have fostered a substantial side benefit: Hospital admissions for chronic obstructive pulmonary disease (COPD) were reduced by 53 percent, according to a new study accepted for publication by a peer-reviewed medical journal and currently available at the online journal medRxiv.

14 Jun 2021

Hair follicle stem cells play an outsize role in healing skin blisters

A team of scientists has shown that the healing of skin blisters is driven by hair follicle stem cells, which delay their own development in the process.

14 Jun 2021

High proportion of people with diabetes have chronic kidney disease, research reveals

Some 42% of patients attending a dedicated diabetes clinic have signs of established chronic kidney disease, the first detailed research of its kind in Ireland has revealed.

14 Jun 2021

Researchers demonstrate an alternative way to produce highly detailed images of the brain

The gold standard in functional brain imaging for over two decades, functional magnetic resonance imaging (fMRI) has transformed the landscape of research and clinical care. Yet, because of its cost and functional limitations, scientists have continued to look for new ways to see into the human brain.

14 Jun 2021

Study: Genetic mutations associated with breast cancer risk are the same in Black and white women

The prevalence of genetic mutations associated with breast cancer in Black and white women is the same, according to a new JAMA Oncology study of nearly 30,000 patients led by researchers in the Basser Center for BRCA at the Abramson Cancer Center. About five percent of both Black and white women have a genetic mutation that increases their risk of breast cancer.

14 Jun 2021

New approach to gene therapy uses common pain reliever to fight against genetic diseases

Researchers have developed a new approach to gene therapy that leans on the common pain reliever acetaminophen to force a variety of genetic diseases into remission.

14 Jun 2021

Artificial intelligence for predicting TMB-H colorectal cancer from histopathological characteristics

Biomarkers are important determinants of appropriate and effective therapeutic approaches for various diseases including cancer.

14 Jun 2021

UIC discovery may lead to new treatments for alcohol use disorder and depression

A discovery from researchers at the University of Illinois Chicago may lead to new treatments for individuals who suffer from alcohol use disorder and depression.

14 Jun 2021

Leducq Foundation provides $7 million to support Cardiac Splicing as a Therapeutic Target project

Diverse messenger RNAs are produced in cells by “alternative splicing.” The Leducq Foundation is now supporting a transatlantic network dedicated to investigating this process in heart muscle cells and how changes in this process contribute to disease. Professor Michael Gotthardt of the MDC and Professor Leslie Leinwand of the University of Colorado Boulder are coordinating the project.

14 Jun 2021

Medicine News and Research

Alkaloids show potential as treatments for COVID-19

Treatment-resistant depression relieved by laughing gas

Weight-based dosing strategy may affect immunotherapy outcomes, shows study

Study uncovers novel drug that effectively thwarts pancreatic tumors

Study reveals risk factors associated with COVID-19 outcomes for people with IDD

Researchers study sick-leave patterns after Covid-19

Stents inspired by kirigami could deliver drugs to tubular organs

COVID-19 public health efforts linked to dramatic decline in COPD hospitalizations

Hair follicle stem cells play an outsize role in healing skin blisters

High proportion of people with diabetes have chronic kidney disease, research reveals

Researchers demonstrate an alternative way to produce highly detailed images of the brain

Study: Genetic mutations associated with breast cancer risk are the same in Black and white women

New approach to gene therapy uses common pain reliever to fight against genetic diseases

Artificial intelligence for predicting TMB-H colorectal cancer from histopathological characteristics

UIC discovery may lead to new treatments for alcohol use disorder and depression

Leducq Foundation provides $7 million to support Cardiac Splicing as a Therapeutic Target project

LSU Health New Orleans Nursing receives HRSA grant to improve mental and behavioral health care

USC study suggests new treatment target for Alzheimer's disease in people with APOE4 gene

Nanoparticle-based therapy alleviates pulmonary hypertension in mouse model of rare lung disease

Kirigami-inspired stent to improve drug delivery for diseases that affect tubular organs

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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