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New technique uses high-throughput sequencing to obtain ultra-high-resolution images of gene expression

The 30,000 or so genes making up the human genome contain the instructions vital to life. Yet each of our cells expresses only a subset of these genes in their daily functioning. The difference between a heart cell and a liver cell, for example, is determined by which genes are expressed--and the correct expression of genes can mean the difference between health and disease.

11 Jun 2021

NCCN experts provide new guidance on COVID-19 vaccines for cancer patients

The National Comprehensive Cancer Network® (NCCN®) today announced the publication of new guidance on COVID-19 vaccines for people with cancer, intended to clear up confusion for patients and caregivers. The new four-page patient guide is based on the latest expert review of evolving evidence.

11 Jun 2021

HEPA air purifier can significantly reduce airborne COVID-19 particles

As COVID-19 restrictions ease nationwide and more people host indoor gatherings, investing in a high efficiency particulate air (HEPA) purifier might not be a bad idea, says a University of Cincinnati College of Medicine researcher.

11 Jun 2021

Incidental rudeness can be deadly in certain situations, suggests study

Have you ever been cut off in traffic by another driver, leaving you still seething miles later? Or been interrupted by a colleague in a meeting, and found yourself replaying the event in your head even after you've left work for the day? Minor rude events like this happen frequently, and you may be surprised by the magnitude of the effects they have on our decision-making and functioning.

11 Jun 2021

Study identifies mechanisms by which COVID-19 can lead to Alzheimer's disease-like dementia

A new Cleveland Clinic-led study has identified mechanisms by which COVID-19 can lead to Alzheimer's disease-like dementia.

11 Jun 2021

Johns Hopkins researcher receives prestigious award for breakthrough research in circadian science

Sleep medicine physician and sleep researcher Dr. Charlene Gamaldo of Johns Hopkins Medicine is the recipient of the inaugural Diversity, Equity and Inclusion Leadership Award from the Associated Professional Sleep Societies, LLC, a joint initiative of the American Academy of Sleep Medicine and the Sleep Research Society.

11 Jun 2021

Statins associated with reduced COVID-19 mortality and decreased need for ventilator support

Statins are medications widely used in the management of cardiovascular diseases and metabolic syndrome. Statins help lower serum lipids by blocking HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-coenzyme A reductase), the rate-limiting enzyme of cholesterol biosynthesis.

11 Jun 2021

Metformin prevents pulmonary or lung inflammation in animals infected with SARS-CoV-2

Metformin is a widely prescribed blood sugar-lowering drug. It is often used as an early therapy (in combination with diet and lifestyle changes) for type 2 diabetes, which afflicts more than 34 million Americans.

11 Jun 2021

Study: cis P-tau is an early marker of vascular dementia, Alzheimer's disease

Researchers remain perplexed as to what causes dementia and how to treat and reverse the cognitive decline seen in patients.

11 Jun 2021

Ketogenic metabolic therapy could work synergistically with IDH1-mutant glioblastoma

A British man who rejected the standard of care to treat his brain cancer has lived with the typically fatal glioblastoma tumor growing very slowly after adopting a ketogenic diet, providing a case study that researchers say reflects the benefits of using the body's own metabolism to fight this particularly aggressive cancer instead of chemo and radiation therapy.

11 Jun 2021

Most behavioral testing does not account for animals’ circadian rhythms, shows survey

Imagine being woken up at 3 a.m. to navigate a corn maze, memorize 20 items on a shopping list or pass your driver's test.

11 Jun 2021

New curriculum assessment tool can efficiently assess incorporation of SGM core competencies

Medical education aspires to mitigate bias in future professionals by providing a robust curriculum that includes perspectives and practices for caring for sexual and gender minority (SGM) populations, including lesbian, gay, bisexual, transgender and intersex (LGBTQI) persons.

11 Jun 2021

AMP’s new consensus can promote standardization of PGx gene/allele testing, improve patient care

The Association for Molecular Pathology (AMP), the premier global, molecular diagnostic professional society, today published consensus recommendations to aid in the design and validation of clinical CYP2D6 assays, promote standardization of testing across different laboratories and improve patient care

11 Jun 2021

New editorial policy allows swift, confidential updates to author names after publication

Journal of Cell Biology (JCB), Journal of Experimental Medicine (JEM), and Journal of General Physiology (JGP) announce an editorial policy allowing swift and confidential updates to author names at any time and for any reason including changes to gender identity, marriage, divorce, religion, or other personal circumstances.

11 Jun 2021

Largest U.S. study shares first results on effects of COVID-19 on cancer patients

In the largest study of its kind to date, researchers analyzing national data from more than 63,000 patients with cancer and a positive COVID-19 diagnosis report an increased risk of death among those who were older, male, had a higher number of comorbidities, and had hematologic cancers and recent chemotherapy treatments.

11 Jun 2021

Study provides treatment options for children with average risk medulloblastoma

Medulloblastoma is a rare but devastating childhood brain cancer. This cancer can spread through the spinal fluid and be deposited elsewhere in the brain or spine.

11 Jun 2021

Macrophages can aid tumor growth by distracting cancer-killing CD8+ T cells

A Ludwig Cancer Research study adds to growing evidence that immune cells known as macrophages inhabiting the body cavities that house our vital organs can aid tumor growth by distracting the immune system's cancer-killing CD8+ T cells.

11 Jun 2021

In vivo protection from emerging SARS-CoV-2 variants by protein nanoparticle vaccine

Researchers in the United States have developed a new coronavirus disease 2019 (COVID-19) vaccine that induced potent neutralizing antibodies against variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in animal models.

10 Jun 2021

Scientists develop new method for single-cell lineage tracing of metastatic cancer

It's often cancer's spread, not the original tumor, that poses the disease's most deadly risk.

10 Jun 2021

Identifying genomic subtypes of pancreatic cancer from histology slides using AI-based tool

AP-HP Greater Paris University Hospitals, the leading European clinical trial center with the largest amount of healthcare data in France dedicated to research and Owkin, a startup pioneering Federated Learning and AI technologies for medical research and clinical development, announced the recent results of their ongoing strategic collaboration at ASCO 2021.

10 Jun 2021

Medicine News and Research

New technique uses high-throughput sequencing to obtain ultra-high-resolution images of gene expression

NCCN experts provide new guidance on COVID-19 vaccines for cancer patients

HEPA air purifier can significantly reduce airborne COVID-19 particles

Incidental rudeness can be deadly in certain situations, suggests study

Study identifies mechanisms by which COVID-19 can lead to Alzheimer's disease-like dementia

Johns Hopkins researcher receives prestigious award for breakthrough research in circadian science

Statins associated with reduced COVID-19 mortality and decreased need for ventilator support

Metformin prevents pulmonary or lung inflammation in animals infected with SARS-CoV-2

Study: cis P-tau is an early marker of vascular dementia, Alzheimer's disease

Ketogenic metabolic therapy could work synergistically with IDH1-mutant glioblastoma

Most behavioral testing does not account for animals’ circadian rhythms, shows survey

New curriculum assessment tool can efficiently assess incorporation of SGM core competencies

AMP’s new consensus can promote standardization of PGx gene/allele testing, improve patient care

New editorial policy allows swift, confidential updates to author names after publication

Largest U.S. study shares first results on effects of COVID-19 on cancer patients

Study provides treatment options for children with average risk medulloblastoma

Macrophages can aid tumor growth by distracting cancer-killing CD8+ T cells

In vivo protection from emerging SARS-CoV-2 variants by protein nanoparticle vaccine

Scientists develop new method for single-cell lineage tracing of metastatic cancer

Identifying genomic subtypes of pancreatic cancer from histology slides using AI-based tool

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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