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Metallic molecule offers real-time monitoring of amyloid plaques in patients with Alzheimer's

A metallic molecule being studied at Rice University begins to glow when bound to amyloid protein fibrils of the sort implicated in Alzheimer's disease. When triggered with ultraviolet light, the molecule glows much brighter, which enables real-time monitoring of amyloid fibrils as they aggregate in lab experiments.

11 Jul 2016

Study identifies new blood markers to accurately diagnose Gulf War Illness

Based on a study of 85 Gulf War veterans, Veterans Affairs researchers in Minneapolis have developed a tentative panel of blood markers they say can verify a diagnosis of Gulf War Illness with 90 percent accuracy.

11 Jul 2016

TBI with LOC linked to late-life neurodegeneration but not Alzheimer's disease

Traumatic brain injury (TBI) with a loss of consciousness (LOC) may be associated with later development of Parkinson's disease but not Alzheimer's disease or incident dementia, according to a study conducted at the Icahn School of Medicine at Mount Sinai and the University of Washington School of Medicine.

11 Jul 2016

Single dose of new molecule could protect the brain from cognitive impairments after mTBI

A new molecule could protect the brain from cognitive impairments after a mild traumatic brain injury, according to Hebrew University of Jerusalem scientists.

11 Jul 2016

Mussels inspire scientists to attach biologically active molecule to titanium surface

Titanium is used medically in applications such as artificial joints and dental implants. While it is strong and is not harmful to tissues, the metal lacks some of the beneficial biological properties of natural tissues such as bones and natural teeth.

11 Jul 2016

Researchers discover new signaling events that trigger metastasis in ovarian cancer cells

Like pancreatic cancer, cancer of the ovaries is notorious for being discovered at a relatively late stage - after it has spread to other sites in the body. It is not called "the silent killer" for nothing.

11 Jul 2016

Scientists identify epigenetic alterations involved in autoinflammatory diseases

Researchers from the Chromatin and Disease group of the Bellvitge Biomedical Research Institute, led by Dr. Esteban Ballestar, have identified for the first time epigenetic alterations in autoinflammatory diseases, particularly in cryopyrin-associated periodic syndromes (CAPS).

8 Jul 2016

Moffitt researchers discover novel way to control SETDB1 protein upregulated in cancer

Cancer is a group of more than 100 different diseases. All are driven by cells and genes that escape the normal process of division and begin their own plan to replicate in the body.

8 Jul 2016

Molecule thought to indicate good cancer prognosis can have dark side, research shows

A molecule which, for the last 20 years has been believed to be an indicator of good prognosis in tumours has been shown to have a dark side by new research from The Universities of Manchester, Athens and collaborators, recently published in Nature Cell Biology.

8 Jul 2016

Aerobic exercise training reestablishes cardiac protein quality control system in heart failure rats

Aerobic exercise training restored the cardiac protein quality control system in rats showed a study recently published in Journal of Cellular and Molecular Medicine.

8 Jul 2016

New methods to examine the brain and spinal fluid could lead to early detection of Alzheimer's disease

New methods to examine the brain and spinal fluid heighten the chance of early diagnosis of Alzheimer's disease. Results from a large European study, led by researchers at the Karolinska Institutet, are now published in the medical journal BRAIN.

8 Jul 2016

Study finds microRNA let-7 plays key role in restricting neuroblastoma

Great strides have been made in treating neuroblastoma, the most common cancer in infants and toddlers. However, advanced cases are often fatal, and children who survive often face life-long physical and intellectual challenges related to their treatment.

8 Jul 2016

Study shows miR-19 helps new neurons in the adult brain stay on track

A small stretch of ribonucleic acid called microRNA could make the difference between a healthy adult brain and one that's prone to disorders including schizophrenia.

8 Jul 2016

Imaging technique could help doctors identify patients who may benefit breast cancer treatment

Cancer Research UK scientists have used imaging techniques as a new way to identify patients who could benefit from certain breast cancer treatments, according to a study published in ONCOTARGET today, (Thursday).

8 Jul 2016

New topical film patch can effectively close dermal wounds, reduce scarring

Currently there is no product available based on polymer film containing active molecules to accelerate dermal wound healing that also reduces the scar formation.

8 Jul 2016

Researchers discover mechanism of gene silencing in hormone-dependent breast cancer cells

Sometimes, the silencing of a gene is as important as its activation. Nonetheless, up to now, most studies on hormone-mediated gene regulation have focused on researching the factors that influence the activation of certain genes. Little attention has been paid to gene silencing.

8 Jul 2016

New genetic test provides rapid diagnosis of mitochondrial disease

Newcastle researchers have developed a genetic test providing a rapid diagnosis of mitochondrial disorders to identify the first patients with inherited mutations in a new disease gene.

7 Jul 2016

Researchers aim to explore impact of gender and aging on CapZ levels in the heart

Why do women have lower rates of heart failure than men for most of their lives? University of Guelph researchers have uncovered a possible clue - an actin binding protein called "CapZ" that also protects against heart attacks.

7 Jul 2016

Mitochondrial stress can trigger tumor-related metabolic shifts, study finds

Cancerous tumors must be fed. Their unregulated growth requires a steady stream of blood flow and nutrients. Thus, one way that researchers have tried to wipe out cancer is to target cells undergoing the metabolic shifts that enable a tumor's rapid growth.

7 Jul 2016

Buck researchers find new way for possible treatment of AMD

Buck researchers boosted the potency of a broccoli-related compound by ten times and identified it as a possible treatment for age-related macular degeneration (AMD), the leading cause of vision loss affecting more than 10 million older Americans.

7 Jul 2016

G Protein News and Research

Metallic molecule offers real-time monitoring of amyloid plaques in patients with Alzheimer's

Study identifies new blood markers to accurately diagnose Gulf War Illness

TBI with LOC linked to late-life neurodegeneration but not Alzheimer's disease

Single dose of new molecule could protect the brain from cognitive impairments after mTBI

Mussels inspire scientists to attach biologically active molecule to titanium surface

Researchers discover new signaling events that trigger metastasis in ovarian cancer cells

Scientists identify epigenetic alterations involved in autoinflammatory diseases

Moffitt researchers discover novel way to control SETDB1 protein upregulated in cancer

Molecule thought to indicate good cancer prognosis can have dark side, research shows

Aerobic exercise training reestablishes cardiac protein quality control system in heart failure rats

New methods to examine the brain and spinal fluid could lead to early detection of Alzheimer's disease

Study finds microRNA let-7 plays key role in restricting neuroblastoma

Study shows miR-19 helps new neurons in the adult brain stay on track

Imaging technique could help doctors identify patients who may benefit breast cancer treatment

New topical film patch can effectively close dermal wounds, reduce scarring

Researchers discover mechanism of gene silencing in hormone-dependent breast cancer cells

New genetic test provides rapid diagnosis of mitochondrial disease

Researchers aim to explore impact of gender and aging on CapZ levels in the heart

Mitochondrial stress can trigger tumor-related metabolic shifts, study finds

Buck researchers find new way for possible treatment of AMD

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