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Study links metal exposure to overweight and obesity in children

Researchers from the Granada Biosanitary Research Institute (ibs.GRANADA) and the University od Granada have revealed positive and negative associations between exposure to a combination of different metals and overweight and obesity in children.

11 Dec 2024

Early exposure to parental smoking linked to higher MS risk

Cutting early life exposure to parental smoking may lower the risk of developing MS (multiple sclerosis) in those who are genetically predisposed to the disease, finds research published online in the Journal of Neurology Neurosurgery & Psychiatry.

11 Dec 2024

Metabolic imaging detects ovarian cancer subtypes and predicts chemotherapy response

Study demonstrates how metabolic imaging differentiates high and low oxidative phosphorylation (OXPHOS) subtypes of high-grade serous ovarian cancer (HGSOC). By assessing metabolic activity, it also identifies early and variable responses to chemotherapy, improving precision in treatment strategies.

10 Dec 2024

ADAMTS13 deficiency drives platelet accumulation in pyrrolizidine alkaloid-induced liver injury

Pyrrolizidine alkaloids (PAs), widely distributed in plants, are known to induce liver failure. Hepatic platelet accumulation has been reported during the progression of PA-induced liver injury (PA-ILI).

10 Dec 2024

New $1.4M grant supports innovative kidney cancer treatment strategy

Weill Cornell Medicine has received a $1.4 million, four-year grant from the U.S. Department of Defense to investigate a new therapeutic approach for the most common form of kidney cancer.

10 Dec 2024

Scientists identify potential therapeutic targets for diabetic kidney disease

New potential therapeutic targets have been identified for diabetic kidney disease (DKD) - the leading cause of kidney failure in the world - that could see patients treated with new gene and drug therapies preventing the disease's progression into end stage kidney failure.

10 Dec 2024

Study unveils how Toxoplasma gondii parasites escape drug treatment

A study by Indiana University School of Medicine researchers sheds new light on how Toxoplasma gondii parasites make the proteins they need to enter a dormant stage that allows them to escape drug treatment.

10 Dec 2024

Two distinct types of fatty liver disease identified

Researchers at Karolinska Institutet and the University of Gothenburg have identified two types of metabolic-associated fatty liver disease - a liver-specific type and a systemic type that affects other organs and tissues.

10 Dec 2024

Women with PCOS and obesity have smaller babies, study finds

Women with polycystic ovary syndrome (PCOS) and obesity are at a higher risk of giving birth to smaller babies in terms of birth weight, length, and head circumference, according to a recent study conducted at the Norwegian University of Science and Technology (NTNU).

10 Dec 2024

Shivering for 1 hour a day may boost glucose tolerance and metabolic health

Daily cold exposure with shivering for 10 days improves glucose tolerance and metabolic health in individuals with obesity, highlighting shivering's role.

10 Dec 2024

Smoking linked to increased genetic mutations in myelodysplastic syndromes

Smokers with myelodysplastic syndromes (MDS) or a precursor condition had elevated levels of genetic mutations linked to the disease, a new study shows.

9 Dec 2024

Study provides the first evidence of genetic predisposition to breast cancer metastasis

Ninety percent of cancer deaths are due to the spread of cancer, not complications from the original tumor.

9 Dec 2024

Study identifies potential risk factor for aortic aneurysms in Loeys-Dietz syndrome

Studying the cells of people and genetically engineered mice, Johns Hopkins Medicine scientists say they have uncovered a potential reason why patients with Loeys-Dietz syndrome, an inherited connective tissue disorder, are especially prone to developing aneurysms at the root of the aorta, the major artery that carries blood away from the heart and to the rest of the body.

9 Dec 2024

X-chromosome study reveals hidden genetic links to Alzheimer’s disease

A groundbreaking study explores the overlooked X-chromosome’s role in Alzheimer’s disease, revealing seven genetic loci linked to neurodegenerative decline and cognitive reserve.

9 Dec 2024

New discovery reveals how exercise boosts muscle energy production

While it is common knowledge that physical exercise is good for us, a lot of the underlying molecular mechanisms remain to be identified.

9 Dec 2024

Pioneering study discovers new genetic links to pancreatic cancer in Brazil

Pancreatic cancer has recently been included in the list of diseases about which Brazil's National Cancer Institute (INCA) periodically publishes statistics.

9 Dec 2024

Developing climate-resilient crops is essential for global food security

Increasing heat, droughts, floods, and salinization caused by climate change are lowering the amount of edible food produced by our staple crops.

9 Dec 2024

Depression genes amplify women's heart disease risk

Study reveals a sex-specific link between genetic risks for psychiatric disorders and cardiovascular diseases (CVDs), with women showing a higher risk of atrial fibrillation, coronary artery disease, and heart failure linked to genetic predisposition to major depression. Menopause and modifiable factors like BMI and smoking amplify these risks.

8 Dec 2024