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Researchers turn a deadly fungus into potent cancer-fighting compound

Penn-led researchers have turned a deadly fungus into a potent cancer-fighting compound. After isolating a new class of molecules from Aspergillus flavus, a toxic crop fungus linked to deaths in the excavations of ancient tombs, the researchers modified the chemicals and tested them against leukemia cells.

23 Jun 2025

Assessment of insulin resistance using TyG index flags rapid cognitive decline in Alzheimer's patients

Insulin resistance detected by routine triglyceride-glucose (TyG) index can flag people with early Alzheimer's who are four times more likely to present rapid cognitive decline, according to new research presented at the European Academy of Neurology (EAN) Congress 2025.

22 Jun 2025

Seafood imports linked to spread of colistin resistance

Colistin is a potent, last-resort antibiotic, used only to treat people with dangerous, life-threatening bacterial infections that have developed resistance to other drugs.

22 Jun 2025

Scientists discover on/off gene switches that could revolutionize personalized medicine

Scientists identified 473 human genes that act as genetic “on/off switches,” shaping disease risk through tissue-specific or universal patterns regulated by DNA changes and hormones. These findings could pave the way for more precise diagnostics and personalized therapies across cancers, immune, skin, and metabolic diseases.

22 Jun 2025

Men lose more weight than women on the keto diet, new study reveals why

Men lose more weight than women on a ketogenic diet, according to a comprehensive review in Frontiers in Nutrition. Sex differences in hormones, metabolism, and fat distribution influence the effectiveness of the ketogenic diet for obesity.

22 Jun 2025

Flies on dairy farms act as hidden carriers of superbugs and zoonotic threats

Researchers used deep metagenomic sequencing to trace zoonotic pathogens and antibiotic resistance genes from cow manure into the guts of muscid flies on a French dairy farm. Findings reveal that flies not only carry but may amplify dangerous microbes, underscoring public health risks.

22 Jun 2025

Formation of tiny living bots can reset the cellular aging clock

Modern humans have existed for over 200,000 years, and each new generation has begun with a single cell-dividing, changing shape and function, organizing into tissues, organs, and limbs.

21 Jun 2025

Healthy gut microbiome before chemo could help protect breast cancer patients against cardiotoxicity

New research suggests that a healthy microbiome before chemotherapy could help protect breast cancer patients against heart damage, or cardiotoxicity, as a result of cancer therapy.

21 Jun 2025

New lab method accelerates diagnosis of genetic disorders of the immune system

A new laboratory method developed by researchers at Columbia University Vagelos College of Physicians and Surgeons may now help physicians more quickly diagnose patients with suspected genetic disorders of the immune system, many who have been trapped in diagnostic limbo for years.

20 Jun 2025

Researchers find unique genetic profile in childhood cancer survivors with cardiomyopathy

Scientists at St. Jude Children’s Research Hospital studied how common and rare genetic variants influence late-onset cardiomyopathy risk, highlighting the unique genetic complexity of childhood cancer survivors.

20 Jun 2025

SFARI releases largest dataset on hospitalized children with autism

The Simons Foundation Autism Research Initiative (SFARI) has released phenotypic and genetic data from the Autism Inpatient Collection (AIC), a cohort of more than 1,500 youth participants ages 4 to 20 years old who were hospitalized in one of six child psychiatry units in the United States.

20 Jun 2025

Histone modification involved in chromosome and spindle stabilization in mouse oocytes

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the next generation.

20 Jun 2025

Driving breakthroughs for the NF community at the 2025 NF Conference

A new era is unfolding for the NF community. With two FDA-approved treatments now on the market - including the first-ever therapy for adults with NF1 - and cutting-edge advances in AI, drug repositioning, and precision medicine, momentum is building like never before.

20 Jun 2025

Scientists develop tool to predict bowel cancer drug resistance

Scientists have developed a tool that can predict how bowel cancer adapts to treatment – helping researchers to design new personalized drugs that will keep patients living well for longer.

20 Jun 2025

Targeted nanoparticles enable in vivo production of CAR T cells for cancer therapy

Researchers present a new method to safely and preferentially generate CAR T cells directly inside the body using targeted lipid nanoparticles that deliver mRNA directly to T cells.

20 Jun 2025

Why Alzheimer’s DNA tests don’t treat all populations equally

A major global study tested whether European-derived polygenic risk scores (PGS) for Alzheimer’s disease can predict risk across diverse populations. While PGS performed well in many groups, it was less accurate in individuals of sub-Saharan African and Indian ancestry, highlighting the urgent need for more inclusive genetic data.

19 Jun 2025

Study: HIV is a flexible cellular hijacker

University of Michigan researchers have uncovered new details of the process that HIV uses to hijack cells’ transportation systems for its own survival.

19 Jun 2025

Researchers identify key differences in Alzheimer's progression in humans and animal models

Although it is known that Alzheimer's disease can start up to 20 years before the first symptoms appear, the lack of knowledge about how it progresses prevents the development of effective treatments, as well as a clear diagnosis to confront this neurodegenerative disease, which origin is also unknown.

19 Jun 2025

NHCS and Mayo Clinic join forces to advance global cardiovascular care

The National Heart Centre Singapore (NHCS) and Mayo Clinic have collaborated under a Memorandum of Understanding (MOU) to accelerate cardiovascular innovation and research, and to foster knowledge for future cardiovascular care worldwide.

19 Jun 2025

Brain age gap may influence the relationship between cognitive impairment risk factors

The difference between the brain's predicted age and actual chronological age, called a brain age gap, may influence the relationship between cognitive impairment risk factors, like high blood pressure and diabetes, and a person's cognitive performance, also known as thinking and memory skills, according to a study published June 18, 2025, in Neurology, the medical journal of the American Academy of Neurology.

19 Jun 2025

Genetic News and Research

Researchers turn a deadly fungus into potent cancer-fighting compound

Assessment of insulin resistance using TyG index flags rapid cognitive decline in Alzheimer's patients

Seafood imports linked to spread of colistin resistance

Scientists discover on/off gene switches that could revolutionize personalized medicine

Men lose more weight than women on the keto diet, new study reveals why

Flies on dairy farms act as hidden carriers of superbugs and zoonotic threats

Formation of tiny living bots can reset the cellular aging clock

Healthy gut microbiome before chemo could help protect breast cancer patients against cardiotoxicity

New lab method accelerates diagnosis of genetic disorders of the immune system

Researchers find unique genetic profile in childhood cancer survivors with cardiomyopathy

SFARI releases largest dataset on hospitalized children with autism

Histone modification involved in chromosome and spindle stabilization in mouse oocytes

Driving breakthroughs for the NF community at the 2025 NF Conference

Scientists develop tool to predict bowel cancer drug resistance

Targeted nanoparticles enable in vivo production of CAR T cells for cancer therapy

Why Alzheimer’s DNA tests don’t treat all populations equally

Study: HIV is a flexible cellular hijacker

Researchers identify key differences in Alzheimer's progression in humans and animal models

NHCS and Mayo Clinic join forces to advance global cardiovascular care

Brain age gap may influence the relationship between cognitive impairment risk factors

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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