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Researchers reveal potential mode of drug resistance in malaria parasites

Scientists have uncovered a potential mode of parasite drug resistance in malaria infection, according to a report published in The Journal of Experimental Medicine.

5 May 2015

Eribulin from marine sponge inhibits replication of breast cancer cells

For more than three decades a new drug for the treatment of breast cancer had not been presented. A group of researchers were given the task of analyzing a marine sponge called Halichondrin okadai and obtained a mesylate eribulin substance that had already been applied to patients with this disease in the stage of metastasis, ie, when the disease spreads to other body parts and the result was that it inhibited tumor growth.

4 May 2015

Researchers suggest ways to keep harmful tobacco and alcohol products away from young people

As the realities of legalized marijuana take hold in four states and the District of Columbia, legislators and regulators could learn a lot from the successes -- and failures -- of the tobacco and alcohol industries in keeping their harmful products out of the hands of children and adolescents.

4 May 2015

DelMar to present new data on development of VAL-083 at 2015 ASCO Annual Meeting

DelMar Pharmaceuticals, Inc., today announced that it will be presenting new data related to the development of lead product candidate VAL-083 (dianhydrogalactitol) at the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, being held May 29-June 2, 2015, in Chicago, Illinois.

30 Apr 2015

UTHealth scientists use new methods to explore naturally occurring 'knockout humans'

Researchers at The University of Texas Health Science Center at Houston are helping to make precision medicine a reality by sequencing entire exomes of people to assess chronic disease risk and drug efficacy. The results of a study on this topic were published in Nature Genetics on Monday.

30 Apr 2015

ITIM-containing receptor crucial for development of acute myeloid leukemia

UT Southwestern Medical Center scientists have discovered that a certain class of receptors that inhibit immune response are crucial for the development of acute myeloid leukemia (AML), the most common acute leukemia affecting adults.

30 Apr 2015

Promising compound blocks production of beta amyloid peptides in Alzheimer's mouse model

Offering a potential early intervention for Alzheimer's disease (AD), researchers at University of California, San Diego School of Medicine and Cenna Biosciences, Inc. have identified compounds that block the production of beta amyloid peptides in mice.

30 Apr 2015

Novel combination therapy shows promise in mouse models of advanced prostate cancer

Chemotherapy can be very effective against small prostate tumors. Larger prostate tumors, however, accumulate cells that suppress the body's immune response, allowing the cancer to grow despite treatment.

30 Apr 2015

Research provides insights into the ability of FL118 to overcome treatment resistance

The latest research from the team that discovered the novel anticancer agent FL118 highlights distinctive characteristics of this small-molecule compound and provides insights into its ability to overcome the persistent problem of treatment resistance. In findings reported in Molecular Cancer, Fengzhi Li, PhD, of Roswell Park Cancer Institute, and colleagues provide new evidence that FL118 may be more effective than two structurally similar injectable drugs and, additionally, may be effective as an oral agent.

30 Apr 2015

Parents share arduous, circuitous journey to get referrals for childhood epilepsy surgery

Having a child diagnosed with epilepsy can be a frightening and confusing time. Now, parents share their arduous and "circuitous" journey to get referrals for pediatric epilepsy surgery once their child's disease stops responding to anti-seizure medications. The UCLA study sheds light on the difficulties parents face obtaining specialty and sub-specialty care for their children during an already stressful time.

30 Apr 2015

Locally procured drugs can be as effective as IQA drugs for treating MDR-TB in Pakistan

Locally-sourced antibiotics can be as effective as 'internationally quality-assured' (IQA) antibiotics for treating multidrug-resistant tuberculosis (MDR-TB) in Pakistan, and may help avoid delays in starting treatment while programmes wait for drugs to arrive from overseas, according to new research published in PLOS ONE.

30 Apr 2015

Papers on antibiotic resistance, neglected diseases and future of the ocean to be discussed during G7 summit

Today the national science academies of the G7 countries handed three statements to their respective heads of government for discussion during the G7 summit at Schloss Elmau in early June 2015. The papers on antibiotic resistance, neglected and poverty-related diseases, and the future of the ocean were drawn up by the seven national academies under the aegis of the German National Academy of Sciences Leopoldina.

30 Apr 2015

Medicure records net revenue of $3.3 million for first quarter 2015

Medicure Inc., a specialty pharmaceutical company, today reported its results from operations for the first quarter ended March 31, 2015.

30 Apr 2015

Patients with adefovir-resistant HBV benefit from TDF monotherapy

Tenofovir disoproxil fumarate alone elicits a response comparable to that of TDF plus entecavir in heavily pretreated patients with chronic hepatitis B virus infection resistant to adefovir dipivoxil, research suggests.

29 Apr 2015

Research findings pave way for development of new treatments for respiratory diseases

The research has discovered a link between a vital pumping system that does not function correctly in people with cystic fibrosis and the parasite Toxoplasma.

29 Apr 2015

Scientists identify new way to predict disease outcomes in people with rheumatoid arthritis

Arthritis Research UK-funded scientists at The University of Manchester have identified a new way in which genotyping can be used to predict disease outcomes among sufferers of rheumatoid arthritis.

29 Apr 2015

Polygamous marriage can increase heart disease risk in men by four times

Polygamy increases the risk of heart disease by more than 4-fold, reveals research presented at the Asian Pacific Society of Cardiology Congress 2015 (APSC 2015) by Dr Amin Daoulah, a cardiologist at the King Faisal Specialist Hospital and Research Centre in Jeddah, Saudi Arabia. The risk and severity of heart disease increased with the number of wives.

29 Apr 2015

Men undergoing circumcision may be at increased risk of infecting female partners with HIV

In the midst of an international campaign to slow the spread of HIV in sub-Saharan Africa, the World Health Organization recommends male circumcision (the surgical removal of foreskin from the penis) which reduces HIV acquisition by 50-60%.

29 Apr 2015

Two world-renowned scientists receive Poland-U.S. Science Award

World-renowned scientists -- Prof. Mariusz Jaskólski of Adam Mickiewicz University in Poznań, Poland, and Dr. Alexander Wlodawer of the National Cancer Institute, USA -- are the first winners of the Poland-U.S. Science Award granted jointly by the Foundation for Polish Science and the American Association for the Advancement of Science, the world's largest scientific association.

29 Apr 2015

Novel subdermal implant delivering potent ARV drugs shows promise in stopping HIV

Is the end of HIV near? Findings published this week in Antimicrobial Agents and Chemotherapy report that a novel, subdermal implant delivering potent antiretroviral (ARV) drugs shows extreme promise in stopping the spread of HIV.

29 Apr 2015

Drugs News and Research

Researchers reveal potential mode of drug resistance in malaria parasites

Eribulin from marine sponge inhibits replication of breast cancer cells

Researchers suggest ways to keep harmful tobacco and alcohol products away from young people

DelMar to present new data on development of VAL-083 at 2015 ASCO Annual Meeting

UTHealth scientists use new methods to explore naturally occurring 'knockout humans'

ITIM-containing receptor crucial for development of acute myeloid leukemia

Promising compound blocks production of beta amyloid peptides in Alzheimer's mouse model

Novel combination therapy shows promise in mouse models of advanced prostate cancer

Research provides insights into the ability of FL118 to overcome treatment resistance

Parents share arduous, circuitous journey to get referrals for childhood epilepsy surgery

Locally procured drugs can be as effective as IQA drugs for treating MDR-TB in Pakistan

Papers on antibiotic resistance, neglected diseases and future of the ocean to be discussed during G7 summit

Medicure records net revenue of $3.3 million for first quarter 2015

Patients with adefovir-resistant HBV benefit from TDF monotherapy

Research findings pave way for development of new treatments for respiratory diseases

Scientists identify new way to predict disease outcomes in people with rheumatoid arthritis

Polygamous marriage can increase heart disease risk in men by four times

Men undergoing circumcision may be at increased risk of infecting female partners with HIV

Two world-renowned scientists receive Poland-U.S. Science Award

Novel subdermal implant delivering potent ARV drugs shows promise in stopping HIV

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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