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Mediterranean diet reduces risk of recurrent heart attacks or strokes

A "Mediterranean" diet, high in fruit, vegetables, fish and unrefined foods, is linked to a lower risk of heart attack and stroke in people who already have heart disease, according to a study of over 15,000 people in 39 countries around the world. The research also showed that eating greater amounts of healthy food was more important for these people than avoiding unhealthy foods, such as refined grains, sweets, desserts, sugared drinks and deep-fried food - a "Western" diet.

25 Apr 2016

Fructose common in western diet can damage brain genes

A range of diseases -- from diabetes to cardiovascular disease, and from Alzheimer's disease to attention deficit hyperactivity disorder -- are linked to changes to genes in the brain. A new study by UCLA life scientists has found that hundreds of those genes can be damaged by fructose, a sugar that's common in the Western diet, in a way that could lead to those diseases.

25 Apr 2016

Sleep loss influences cholesterol metabolism, study finds

Lack of sleep has previously been found to impact the activation of the immune system, inflammation, carbohydrate metabolism and the hormones that regulate appetite. Now University of Helsinki researchers have found that sleep loss also influences cholesterol metabolism.

22 Apr 2016

Under-expressed miR-9 gene may contribute to schizophrenia risk

By turning skin cells into brain neurons, researchers at the Icahn School of Medicine at Mount Sinai have identified that certain tiny molecules aiding in gene expression, known as microRNAs (miRNAs), are under-expressed in the brains of the 14 schizophrenia patients they studied. Their findings, published online today in the journal Cell Reports, show that one of these molecules, a miRNA known as miR-9, is a risk factor that controls the activity of hundreds of genes.

22 Apr 2016

Long way to go in better understanding brain abnormalities linked with autism

A recent review that examined all published studies on anatomical abnormalities in the brains of individuals with Autism Spectrum Disorder found substantial discrepancy throughout the literature regarding the reported presence and significance of neuroanatomical findings.

22 Apr 2016

Higher levels of neighborhood greenness linked to lower chronic disease risk

A new study of a quarter-million Miami-Dade County Medicare beneficiaries showed that higher levels of neighborhood greenness, including trees, grass and other vegetation, were linked to a significant reduction in the rate of chronic illnesses, particularly in low-to-middle income neighborhoods.

22 Apr 2016

CUMC researchers identify new neurodevelopmental syndrome

A multicenter research team led by Columbia University Medical Center has discovered a new neurodevelopmental syndrome and the genetic mutations that cause it. The discovery is an important step toward creating targeted therapies for individuals with this syndrome, which causes severe developmental delays, abnormal muscle tone, seizures, and eye complications.

22 Apr 2016

Study links duration, timing of sleep to cardiovascular health

No one is telling you what time to go to bed with this, but researchers are making a strong case that the duration and timing of your sleep are closely associated with whether your behavior is heart-healthy.

22 Apr 2016

Researchers determine 3-D structure of RlmN protein from bacteria

The structure of a bacterial RNA-binding protein has been determined in the act of modifying a molecule of RNA -- an achievement that provides researchers with a unique view of the protein's function in action and could lead to clues that would help in the fight against the development of antibiotic-resistant infections.

22 Apr 2016

More cautious blood pressure-lowering strategy may be reasonable for elderly CKD patients

New research indicates that higher systolic blood pressure is linked with poor outcomes in patients with kidney disease, although the association diminishes with advanced age. The findings, which come from a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN), provide valuable information concerning patients who are often excluded from blood pressure-lowering clinical trials.

22 Apr 2016

Increasing specialist community services reduces suicide rates in NHS mental health services in England

Increasing specialist community services like crisis resolution, helping make the transition to adult services smoother for young people, and implementing clinical guidelines are just some of the service changes that are linked to significantly reduced suicide rates in mental health services in England over the last 16 years, according to new research published in The Lancet Psychiatry journal.

22 Apr 2016

Bosutinib shows 'low' vascular, cardiac event risk profile

Third-generation tyrosine kinase inhibitor study findings suggest that bosutinib is associated with a low risk of vascular and cardiac events in patients undergoing first-line or subsequent treatment for chronic myeloid leukaemia.

21 Apr 2016

Scientists uncover unique cellular defects linked with SLOS using novel stem-cell model

Studies performed by a Sanford Research scientist using an innovative stem-cell model for a fatal developmental disorder is the focus of a recent study published in Nature Medicine. Kevin Francis, Ph.D. uncovered unique cellular defects associated with Smith-Lemli-Opitz syndrome (SLOS) by modeling this disease using induced pluripotent stem cells.

21 Apr 2016

Antidepressant Wellbutrin linked to long-term modest weight loss

Group Health researchers have found that bupropion (marketed as Wellbutrin) is the only antidepressant that tends to be linked to long-term modest weight loss.

21 Apr 2016

Testosterone may lead to greater heart attack risk in men than women

Testosterone might be involved in explaining why men have a greater risk of heart attacks than women of similar age, according to a study funded by the British Heart Foundation and the Biotechnology and Biological Sciences Research Council. The findings, published in the journal Scientific Reports, could lead to new therapies to help reduce heart attack risk.

21 Apr 2016

Caltech researchers map out pathways of neurons responsible for Parkinson's motor impairments

Because billions of neurons are packed into our brain, the neuronal circuits that are responsible for controlling our behaviors are by necessity highly intermingled. This tangled web makes it complicated for scientists to determine exactly which circuits do what. Now, using two laboratory techniques pioneered in part at Caltech, Caltech researchers have mapped out the pathways of a set of neurons responsible for the kinds of motor impairments--such as difficulty walking--found in patients with Parkinson's disease.

21 Apr 2016

Scientists find interaction between amyloid and tau proteins that cause brain damage linked with AD

For years, neuroscientists have puzzled over how two abnormal proteins, called amyloid and tau, accumulate in the brain and damage it to cause Alzheimer's disease (AD). Which one is the driving force behind dementia? The answer: both of them, according to a new study by researchers at the Douglas Mental Health University Institute.

21 Apr 2016

Novel gene therapy can improve symptoms of Bubble Boy disease in young adults

Adolescents and young adults with a severe inherited immunodeficiency disorder improved following treatment with novel gene therapy developed at St. Jude Children's Research Hospital and at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. The results of this study appear today in the journal Science Translational Medicine.

21 Apr 2016

Scientists identify genetic variants that may influence wellbeing, depression and neuroticism

An international group of more than 190 scientists who analyzed the genomes of 298,420 individuals have found genetic variants that may influence our sense of wellbeing, depression and neuroticism.

21 Apr 2016

Mother’s misperception of child's weight status linked to childhood obesity or malnutrition

A new study from the University of Houston Department of Health and Human Performance finds a child's risk for obesity or malnutrition may be tied to the mother's misperception of her child's weight status. A key to understanding this phenomenon may lie in how she regards her own weight status. Researchers say the situation shows that healthcare providers need to broaden their health care screenings.

21 Apr 2016

X linked News and Research

Mediterranean diet reduces risk of recurrent heart attacks or strokes

Fructose common in western diet can damage brain genes

Sleep loss influences cholesterol metabolism, study finds

Under-expressed miR-9 gene may contribute to schizophrenia risk

Long way to go in better understanding brain abnormalities linked with autism

Higher levels of neighborhood greenness linked to lower chronic disease risk

CUMC researchers identify new neurodevelopmental syndrome

Study links duration, timing of sleep to cardiovascular health

Researchers determine 3-D structure of RlmN protein from bacteria

More cautious blood pressure-lowering strategy may be reasonable for elderly CKD patients

Increasing specialist community services reduces suicide rates in NHS mental health services in England

Bosutinib shows 'low' vascular, cardiac event risk profile

Scientists uncover unique cellular defects linked with SLOS using novel stem-cell model

Antidepressant Wellbutrin linked to long-term modest weight loss

Testosterone may lead to greater heart attack risk in men than women

Caltech researchers map out pathways of neurons responsible for Parkinson's motor impairments

Scientists find interaction between amyloid and tau proteins that cause brain damage linked with AD

Novel gene therapy can improve symptoms of Bubble Boy disease in young adults

Scientists identify genetic variants that may influence wellbeing, depression and neuroticism

Mother’s misperception of child's weight status linked to childhood obesity or malnutrition

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