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Johns Hopkins researchers create the largest library of brain cells from ALS patients

Researchers at Johns Hopkins Medicine have transformed skin cells from patients with Lou Gehrig’s disease, or amyotrophic lateral sclerosis (ALS), into brain cells affected by the progressive, fatal disease and deposited those human-made cells into the first public ALS cell library, enabling scientists to better study the disease.

15 Apr 2015

Experts to make roadmap for future research, clinical trials for SCLC patients at IASLC workshop

Small cell lung cancer (SCLC) will be the concentrated focus when 100 global experts in the field meet for a workshop hosted by the International Association for the Study of Lung Cancer on April 22-24, 2015 at Memorial Sloan Kettering Cancer Center in New York City.

15 Apr 2015

Clyde Biosciences, a leading drug toxicity testing company, closes Series A investment

Clyde Biosciences Ltd. (Clyde Biosciences) has announced a £2 million ‘Series A’ investment led by Epidarex Capital, a leading international early-stage life science venture capital fund. Scottish Enterprise’s investment arm, the Scottish Investment Bank, also participated in the round along with Glasgow University Holdings, Ltd.

14 Apr 2015

New pre-validated fluorinated fragment library boosts drug screening efficiency

Researchers engaged in drug discovery can now benefit from a new library of fluorinated compounds with superior drug-like characteristics...

From Thermo Fisher Scientific Inc. 14 Apr 2015

LaVision BioTec reports on the Beatson Institute for Cancer Research and their use of multiphoton microscopy to understand the behaviour of cells in cancer metastasis

LaVison BioTec, developers of advanced microscopy solutions for the life sciences, report on the research of Professor Kurt I Anderson and his groups' studies of cell migration in the context of cancer metastasis at the Beatson Institute for Cancer Research...

14 Apr 2015

Women in science: an interview with Professor Dame Carol Robinson, University of Oxford

Professor Dame Carol Robinson has just been announced as the “L’Oréal-UNESCO For Women In Science” European Laureate for 2015...

14 Apr 2015

Managing autosomal dominant polycystic kidney disease: an interview with Dr Richard Sandford, University of Cambridge

Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common inherited kidney diseases. It's also one of the most common reasons that people require dialysis or transplantation...

13 Apr 2015

ACA calls for 'conservative care first' approach to low-back pain

The American Chiropractic Association, in response to recent research calling into question the efficacy of acetaminophen in the management of spinal pain, strongly encourages patients and healthcare providers to consider the benefits of a conservative approach to back pain.

13 Apr 2015

Eisai, Arena complete two Phase 1 registrational trials for once-daily formulation of lorcaserin

Eisai Inc. and Arena Pharmaceuticals, Inc. today announced the completion of two Phase 1 registrational clinical trials that Eisai and Arena believe demonstrate bioequivalence of an investigational once-daily extended release formulation of lorcaserin, as compared to the twice-daily immediate release formulation approved by the US Food and Drug Administration and marketed as BELVIQ.

13 Apr 2015

MSK begins CAR T cell clinical trial for children with relapsed or treatment-resistant ALL

Researchers from Memorial Sloan Kettering Cancer Center are pioneering a new groundbreaking clinical trial for children and young adults with relapsed or treatment-resistant acute lymphocytic leukemia (ALL) by using one of the most promising methods of cancer treatment today, chimeric antigen receptor (CAR) T cells.

12 Apr 2015

TGen scientists discover the likely cause of rare type of muscle weakness in six children

Scientists at the Translational Genomics Research Institute (TGen), using state-of-the-art genetic technology, have discovered the likely cause of a child's rare type of severe muscle weakness.

10 Apr 2015

New combination therapy holds promise for treating HER2-positive breast cancer

Resistance to therapy is a major problem in the cancer field. Even when a treatment initially works, the tumors often find ways around the therapy.

10 Apr 2015

Oxis International resumes trading of common stock on Euronext Paris on April 14, 2015

Oxis International, Inc., a biotechnology company focused on cancer therapy development and commercialization, announced today that trading in its common stock will resume on Euronext Paris on April 14, 2015.

10 Apr 2015

Subpopulation of tumor cells make melanoma aggressive

KU Leuven researchers have zeroed in on what makes cancer cells in melanoma so aggressive. They also succeeded in taming the effect in cell cultures.

10 Apr 2015

Clinical research studies improve medical care, allow access to new therapies

Clinical research studies are the reason medical care has improved leaps and bounds in the past few decades. Without these carefully-designed tests for new drugs, procedures or devices, treatments for diseases would not progress. These studies should be viewed as opportunities, although some people may view them negatively.

10 Apr 2015

Fraunhofer researchers develop cell-free substrate made of advanced fibers

Regenerative medicine uses cells harvested from the patient's own body to heal damaged tissue. Fraunhofer researchers have developed a cell-free substrate containing proteins to which autologous cells bind and grow only after implantation.

10 Apr 2015

Vascular mimicry can spread breast cancer to other sites

Imitation may be the sincerest form of flattery, but it can also have deadly consequences, at least when it comes to tumor cells.

10 Apr 2015

Bionomics to present BNC105 trial results of metastatic renal cancer at Asian Oncology Summit

Bionomics Limited (ASX: BNO, OTCQX: BNOEF) today announced that it will present a poster with new data on the DisrupTOR-1 trial of BNC105 in patients with metastatic renal cancer at the 7th Asian Oncology Summit being held from April 10-12, 2015 in Shanghai, China.

10 Apr 2015

Study explores the impact of costly hepatitis C drugs on Rhode Island's prison system

A new study finds that effective new hepatitis C drugs are so expensive the state of Rhode Island would have to spend almost twice its entire prison health budget to treat all its chronically infected inmates.

10 Apr 2015

Stem cell disease model reveals how tumor suppressor may drive bone cancer

Using induced pluripotent stem cells (iPSCs), a team led by Mount Sinai researchers has gained new insight into genetic changes that may turn a well known anti-cancer signaling gene into a driver of risk for bone cancers, where the survival rate has not improved in 40 years despite treatment advances.

10 Apr 2015

Drugs News and Research

Johns Hopkins researchers create the largest library of brain cells from ALS patients

Experts to make roadmap for future research, clinical trials for SCLC patients at IASLC workshop

Clyde Biosciences, a leading drug toxicity testing company, closes Series A investment

New pre-validated fluorinated fragment library boosts drug screening efficiency

LaVision BioTec reports on the Beatson Institute for Cancer Research and their use of multiphoton microscopy to understand the behaviour of cells in cancer metastasis

Women in science: an interview with Professor Dame Carol Robinson, University of Oxford

Managing autosomal dominant polycystic kidney disease: an interview with Dr Richard Sandford, University of Cambridge

ACA calls for 'conservative care first' approach to low-back pain

Eisai, Arena complete two Phase 1 registrational trials for once-daily formulation of lorcaserin

MSK begins CAR T cell clinical trial for children with relapsed or treatment-resistant ALL

TGen scientists discover the likely cause of rare type of muscle weakness in six children

New combination therapy holds promise for treating HER2-positive breast cancer

Oxis International resumes trading of common stock on Euronext Paris on April 14, 2015

Subpopulation of tumor cells make melanoma aggressive

Clinical research studies improve medical care, allow access to new therapies

Fraunhofer researchers develop cell-free substrate made of advanced fibers

Vascular mimicry can spread breast cancer to other sites

Bionomics to present BNC105 trial results of metastatic renal cancer at Asian Oncology Summit

Study explores the impact of costly hepatitis C drugs on Rhode Island's prison system

Stem cell disease model reveals how tumor suppressor may drive bone cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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