Cancer Therapy News and Research

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Clinical review examines benefit of RT in breast cancer patients with BRCA1, BRCA2 mutations

In light of conflicting and inconclusive clinical data on the benefit of radiation therapy in cancer patients with the BRCA1 and BRCA2 mutation, a clinical review examined the current status of data regarding BRCA1 and BRCA2 deficiency and radiation therapy sensitivity and a potential strategy to intensify the effects of radiation therapy (RT) by poly(ADP-ribose) polymerase inhibitors (PARPi), the pharmacologic drugs under investigation as monotherapy for the treatment of breast cancer in patients with BRCA1 and BRCA2 mutations.

9 Mar 2016

Reconstructive surgery using custom-made spinal rods may improve outcomes

Custom fit is the key when it comes to spinal implant rods, which an estimated 38,000 people need each year. This need is especially great for people who have a spinal deformity such as scoliosis, which causes the spine to twist and turn into complex and sometimes dangerous positions. In 2011, an estimated 1.6 million people received treatment for scoliosis according to the Bone and Joint Initiative, a consortium of professional medical societies.

9 Mar 2016

Drug-incorporated nanoparticle platforms allow for selective targeting of cancer cells

Cancer is a group of diseases characterized by the uncontrolled growth and spread of abnormal cells. It is a leading cause of death and the burden is expected to grow worldwide due to the growth and aging of the population, mainly in less developed countries, in which about 82% of the world's population resides. By 2030, the global burden is expected to grow to 21.7 million new cancer cases and 13 million cancer deaths simply due to the growth and aging of the population. Current cancer therapy approaches are based in surgery, radiotherapy and chemotherapy, being the chemotherapy the one that shows the greater efficiency for cancer treatment, mainly in more advanced stages. A major problem with this conventional chemotherapy is its toxicity and it also destroys healthy tissues resulting in systemic toxicity besides beneficial characteristics of killing cancer cells. Anticancer drugs also destroy healthy tissues resulting in systemic toxicity.

8 Mar 2016

ACGT awards new research grants to take researchers to next level in cancer treatment

Alliance for Cancer Gene Therapy, the nation's only nonprofit dedicated exclusively to cell and gene therapies for cancer, is delighted to announce the recipients of its 2016 ACGT Young Investigator Grants.

8 Mar 2016

CTRC study provides new insight into how Angelina Jolie gene functions in normal breast tissue

Scientists from the Cancer Therapy & Research Center in San Antonio today (March 4) published work that provides deeper insight into how the Angelina Jolie gene, BRCA1, functions in normal breast tissue and how its loss results in breast cancer.

7 Mar 2016

Johns Hopkins Greenberg Bladder Cancer Institute awards grants for 10 bladder cancer research projects

A study of obesity and related metabolic changes on bladder cancer incidence and deaths, and a plan to use stem cells to grow novel urinary tubes are among 10 research projects awarded funding by the Johns Hopkins Greenberg Bladder Cancer Institute.

7 Mar 2016

Expression of BIRC3 protein associated with poor survival, recurrent disease in GBM patients

Glioblastoma multiforme (GBM) is a highly aggressive brain tumor with low survival rates, with newly diagnosed patients surviving a median of 14 months and recurrent patients surviving a median of only 3 to 9 months. New therapeutic targets and biomarkers for prognosis are urgently needed.

7 Mar 2016

Means to target all tumor cells with one treatment uncovered

Research sponsored by Cancer Research UK has identified mutations common to all tumour cells. Immunotherapies specific for these mutations could deliver chemotherapeutic agents to all tumour cells and destroy them.

4 Mar 2016

Varian to collaborate with several Brazilian institutions to train healthcare professionals on radiotherapy technology

Varian Medical Systems, today announced its intent to collaborate with several cancer treatment centers in Brazil for the training of healthcare professionals on advanced radiotherapy technologies.

4 Mar 2016

U-M researchers develop novel mouse model of children's brain cancer

Children with brain cancer may soon get some help from mice with the same disease, thanks to new research from University of Michigan Medical School scientists and their colleagues.

3 Mar 2016

Researchers find Achilles' heel of acute lymphoblastic leukemia

Researchers at The Ottawa Hospital and the University of Ottawa have found the Achilles' heel of one of the most aggressive forms of leukemia that affects both children and adults. They have also identified a possible new treatment that exploits this fatal weakness.

2 Mar 2016

First-ever research programme launched to tackle superbugs

To meet the challenge of the rise in antibiotic resistant bacteria, national charity ‘Antibiotic Research UK is commissioning the first ever research programme to screen antibiotic resistance breakers against antibiotic resistance in Gram-negative bacteria.

2 Mar 2016

New combination treatment shows promise for treating acute myeloid leukaemia

Walter and Eliza Hall Institute researchers have discovered that the treatment of the most deadly form of blood cancer may be improved by combining two recently developed drugs.

1 Mar 2016

Queen's University leads world's first trial of new combination treatment for advanced prostate cancer

Queen's University Belfast, in partnership with the Belfast Trust, is leading the world's first ever trial of a new combination of cancer therapies for patients with advanced prostate cancer, with the hope of prolonging their lives.

26 Feb 2016

Researchers launch clinical trials to test novel cellular-immunotherapy to treat three types of blood cancer

Cancer immunology is based upon boosting the body's own immune system to vanquish malignancies. It is among the fastest growing areas of oncology research. Researchers at UC San Diego Moores Cancer Center have launched three clinical trials to test the safety and efficacy of a novel cellular-immunotherapy that uses modified T cells - one of the immune system's primary weapons - to treat three different types of blood cancer that often defy existing therapies.

24 Feb 2016

Immunotherapy emerges as promising strategy for treatment of brain tumors

For decades most cancers have been treated with a core standard of treatments that include surgery, radiation, and chemotherapy. Now, immunotherapy—a type of treatment that harnesses the patient's immune system to combat the disease—represents the future of cancer treatment, with its efficacy being demonstrated in even the most aggressive types of cancer.

24 Feb 2016

New clinical trial launched to test potential drug that could help immune system combat cancer

Cancer Research UK's Centre for Drug Development, in partnership with Amgen Inc., has launched a new clinical trial to test a drug that could stop a patient's immune system from protecting tumours.

24 Feb 2016

UCLA researchers pioneer more effective approach to improve cancer treatment

Despite a growing interest in developing non-invasive methods to identify rare cancer cells or cancer cell DNA in blood, current techniques remain complicated and often prohibitively expensive. Now, UCLA researchers have pioneered a more effective approach to these "liquid biopsies" that has the potential to offer a streamlined and low-cost solution for people with the disease.

23 Feb 2016

Pfizer’s IBRANCE (palbociclib) now approved for use in women with HR+, HER2- metastatic breast cancer

Pfizer Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved a new indication expanding the use of IBRANCE (palbociclib) 125mg capsules, Pfizer’s metastatic breast cancer therapy.

23 Feb 2016

Australian researchers reveal how nutlins pave way for improving future of cancer treatment

Australian researchers have resolved a mystery about how a promising new class of anti-cancer drugs, called nutlins, work - paving the way for improving the future of cancer treatment.

22 Feb 2016

Cancer Therapy News and Research

Clinical review examines benefit of RT in breast cancer patients with BRCA1, BRCA2 mutations

Reconstructive surgery using custom-made spinal rods may improve outcomes

Drug-incorporated nanoparticle platforms allow for selective targeting of cancer cells

ACGT awards new research grants to take researchers to next level in cancer treatment

CTRC study provides new insight into how Angelina Jolie gene functions in normal breast tissue

Johns Hopkins Greenberg Bladder Cancer Institute awards grants for 10 bladder cancer research projects

Expression of BIRC3 protein associated with poor survival, recurrent disease in GBM patients

Means to target all tumor cells with one treatment uncovered

Varian to collaborate with several Brazilian institutions to train healthcare professionals on radiotherapy technology

U-M researchers develop novel mouse model of children's brain cancer

Researchers find Achilles' heel of acute lymphoblastic leukemia

First-ever research programme launched to tackle superbugs

New combination treatment shows promise for treating acute myeloid leukaemia

Queen's University leads world's first trial of new combination treatment for advanced prostate cancer

Researchers launch clinical trials to test novel cellular-immunotherapy to treat three types of blood cancer

Immunotherapy emerges as promising strategy for treatment of brain tumors

New clinical trial launched to test potential drug that could help immune system combat cancer

UCLA researchers pioneer more effective approach to improve cancer treatment

Pfizer’s IBRANCE (palbociclib) now approved for use in women with HR+, HER2- metastatic breast cancer

Australian researchers reveal how nutlins pave way for improving future of cancer treatment

Your guide to microplate readers for cancer research eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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