OCT News and Research

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Lung cancer-associated fibroblasts could guide the design of personalized treatments

Three subtypes of cancer-associated fibroblasts (CAF) could guide the design of personalized treatment for lung cancer patients, according to a new study in Cancer Cell led by researchers at Massachusetts General Hospital.

26 Oct 2021

Study finds significant surge in liver transplantation for alcoholic hepatitis during the pandemic

Registrations for the national organ transplant waiting list related to alcoholic hepatitis as well as the number of deceased donor liver transplants for the inflammatory liver condition rose significantly during the pandemic, Michigan Medicine researchers found.

26 Oct 2021

Clinically significant cataract associated with greater mortality risk from vascular causes

Clinically significant cataract is associated with an increased risk of death from vascular causes, such as stroke and heart attack, suggests research published online in the British Journal of Ophthalmology.

26 Oct 2021

New treatment for HPV-associated oropharynx cancer leads to excellent disease control, less side effects

Mayo Clinic researchers have found that a new, shorter treatment for patients with HPV-associated oropharynx cancer leads to excellent disease control and fewer side effects, compared to standard treatment.

26 Oct 2021

Safer, more effective therapies could help fight the obesity epidemic

Novel obesity treatments such as modulation of the gut microbiome and gene therapy are underutilized and could help fight the obesity epidemic, according to a new manuscript published in the Endocrine Society's journal, Endocrine Reviews.

26 Oct 2021

Study finds potentially long-lasting impact of the pandemic on scientists

More than a year-and-a-half after the onset of the COVID-19 pandemic, the scientific community is still feeling the effects of the vastly disruptive event - and may for many years to come.

26 Oct 2021

UCL researchers record sharpest images ever of living bacteria

The sharpest images ever of living bacteria have been recorded by UCL researchers, revealing the complex architecture of the protective layer that surrounds many bacteria and makes them harder to be killed by antibiotics.

25 Oct 2021

Researchers reveal mechanism which allows antibiotics like penicillin to kill MRSA

The mechanism which allows β-lactam antibiotics, including penicillin, to kill MRSA has been revealed for the first time.

25 Oct 2021

Researchers identify genes that cause resistance to treatment of Candida glabrata fungus

It is estimated that 80% of women will suffer from vaginal candidiasis at least once in their lives. In addition to superficial infections, which can be oral or vaginal and do not usually have a serious prognosis, fungi of the Candida genus can cause systemic diseases in immunocompromised individuals and these are fatal in 40% of cases.

25 Oct 2021

New data reveals safety, efficacy of nusinersen drug delivery method for SMA patients with advanced disease

A recently published paper details the safety and efficacy of nusinersen administration via a subcutaneous intrathecal catheter system (SIC) for SMA patients with advanced disease.

25 Oct 2021

CODA trial: Antibiotics now accepted as first-line treatment for people with appendicitis

Antibiotics are now an accepted first-line treatment for most people with appendicitis, according to final results of the Comparing Outcomes of antibiotic Drugs and Appendectomy (CODA) trial, and an updated treatment guideline for appendicitis from the American College of Surgeons.

25 Oct 2021

Predictive language models' underlying function more closely resembles the human brain

In the past few years, artificial intelligence models of language have become very good at certain tasks. Most notably, they excel at predicting the next word in a string of text; this technology helps search engines and texting apps predict the next word you are going to type.

25 Oct 2021

Stimulant use linked with increased risk of cardiovascular events among older adults in the first month

New research led by Mina Tadrous, Assistant Professor, Leslie Dan Faculty of Pharmacy, University of Toronto shows that use of prescription stimulant medications in older adults increased the risk of a cardiovascular events by 40 per cent within the first thirty days of medication use.

25 Oct 2021

Researchers develop ferritin-based nanomedicine for targeted delivery of leukemia therapy

Researchers from the Institute of Process Engineering\ of the Chinese Academy of Sciences, Peking University and Zhujiang Hospital of Southern Medical University have developed a ferritin (Fn)-based nanomedicine for targeted delivery of arsenic (As) and efficient therapy against diverse leukemia types.

25 Oct 2021

‘Smart bandage’ could help doctors to monitor chronic wounds more easily

How can doctors make sure a dressed wound is healing without taking off the bandage? This is a conundrum, because removing a bandage can disrupt the healing process.

25 Oct 2021

Researchers investigate SARS-CoV-2 specific immunity in young Swedish adults

Researchers at Karolinska Institutet in Sweden have analyzed the presence of SARS-CoV-2-specific antibodies and memory cells of the immune system in young adults.

25 Oct 2021

Study provides a specific target to tackle breast cancer relapse

Molecular targets for therapies that could prevent breast cancer recurrence have been identified by a group of German, Norwegian and British scientists who analyzed tumour cells that proved resistant to the original treatment.

25 Oct 2021

Nanoparticle-mediated, slow-release delivery of TT-10 enhances heart attack recovery in mouse model

A heart attack kills heart muscle cells, leading to a scar that weakens the heart, often leading to eventual heart failure. The lack of muscle repair is due to the very limited ability of mammalian heart muscle cells to proliferate, except for a brief period around birth.

25 Oct 2021

Scientists show how cold could alleviate multiple sclerosis symptoms

In evolutionary biology, the "Life History Theory", first proposed in the 1950s, postulates that when the environment is favorable, the resources used by any organism are devoted for growth and reproduction.

25 Oct 2021

Rutgers study links genetic disorders to walking patterns

Rutgers researchers have linked the genetic disorders Fragile X and SHANK3 deletion syndrome – both linked to autism and health problems – to walking patterns by examining the microscopic movements of those wearing motion-sensored sneakers.

25 Oct 2021

OCT News and Research

Lung cancer-associated fibroblasts could guide the design of personalized treatments

Study finds significant surge in liver transplantation for alcoholic hepatitis during the pandemic

Clinically significant cataract associated with greater mortality risk from vascular causes

New treatment for HPV-associated oropharynx cancer leads to excellent disease control, less side effects

Safer, more effective therapies could help fight the obesity epidemic

Study finds potentially long-lasting impact of the pandemic on scientists

UCL researchers record sharpest images ever of living bacteria

Researchers reveal mechanism which allows antibiotics like penicillin to kill MRSA

Researchers identify genes that cause resistance to treatment of Candida glabrata fungus

New data reveals safety, efficacy of nusinersen drug delivery method for SMA patients with advanced disease

CODA trial: Antibiotics now accepted as first-line treatment for people with appendicitis

Predictive language models' underlying function more closely resembles the human brain

Stimulant use linked with increased risk of cardiovascular events among older adults in the first month

Researchers develop ferritin-based nanomedicine for targeted delivery of leukemia therapy

‘Smart bandage’ could help doctors to monitor chronic wounds more easily

Researchers investigate SARS-CoV-2 specific immunity in young Swedish adults

Study provides a specific target to tackle breast cancer relapse

Nanoparticle-mediated, slow-release delivery of TT-10 enhances heart attack recovery in mouse model

Scientists show how cold could alleviate multiple sclerosis symptoms

Rutgers study links genetic disorders to walking patterns

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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