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Blocking fat-busting enzyme with a drug compromises cardiac repair during acute heart failure

Blocking the fat-busting enzyme lipoxygenase with a synthetic inhibitor throws the immune system's innate inflammatory response out of whack, compromising cardiac repair during acute heart failure, USF Health researchers found.

10 May 2021

Point-of-care ultrasonography can improve the correctness of diagnosis in patients with acute dyspnea

Point-of-Care UltraSonography (POCUS) deployed during the emergency treatment of patients with acute dyspnea has enormous advantages over standard diagnostic pathways.

10 May 2021

Esophageal cancers turn on ancient viral DNA hidden in our genome

Scientists have discovered that many esophageal cancers turn on ancient viral DNA that was embedded in our genome hundreds of millions of years ago.

10 May 2021

New technique can help to non-invasively assess progression of sickle cell retinopathy

Ophthalmologists at New York Eye and Ear Infirmary of Mount Sinai have created a new technique to evaluate patients with sickle cell retinopathy and assess the disease before it progresses and leads to permanent vision loss.

10 May 2021

Korea's first large-scale project reaches milestone of sequencing 10,000 whole genomes

On April 26, UNIST and Ulsan City officially announced that their ambitious 10,000 Genome Project has finally reached the milestone of sequencing 10,000 whole genomes.

10 May 2021

Cardiovascular risk factors accumulated from childhood linked to poorer brain function at midlife

Managing weight, blood pressure and cholesterol in children may help protect brain function in later life, according to new research published today in the American Heart Association's flagship journal Circulation.

10 May 2021

Scientists produce a universal flu vaccine using nanoparticles to induce long-lasting immunity

Researchers at the National Institute of Allergy and Infectious Diseases (NIAID)’s Vaccine Research Center (VRC) and the University of Washington School of Medicine’s Institute for Protein Design (IPD) developed a universal flu vaccine candidate using small particles (nanoparticles), which can induce a long-lasting immune response.

10 May 2021

Cardiac complications found to be rare in college athletes who contracted COVID-19

In a small study, researchers found college athletes who contracted COVID-19 rarely had cardiac complications. Most had mild COVID symptoms that did not require treatment, and in a small percentage of those with abnormal cardiac testing, there was no evidence of heart damage on special imaging tests.

10 May 2021

Total COVID-19 deaths could be 7 million

A new analysis from the Institute for Health Metrics and Evaluation (IHME), which independently researches health at the University of Washington School of Medicine, shows that the total global toll due to coronavirus disease 2019 (COVID-19) could be more than twice the officially reported number of deaths, at almost 7 million.

10 May 2021

New "molecular tweezers" can help combat antibiotic-resistant bacteria

Researchers from Ben-Gurion University (BGU), together with American and German colleagues, have developed new "molecular tweezers" to combat antibiotic-resistant bacteria. Their recently announced findings were published in Cell Chemical Biology.

10 May 2021

Is COVID-19 a new disease?

In a review recently published in The Lancet Respiratory Medicine journal by Osuchowski et al. (May 6th, 2021) the currently known pathophysiology of COVID-19 is laid out to describe the mechanistic features that make COVID-19 distinct from many conditions previously thought to be similar.

9 May 2021

Researchers identify anti-inflammatory prodrug Minnelide with potential against SARS-CoV-2

Using a transgenic mouse model of COVID-19, they have observed that treatment with Minnelide reduces viral load and inflammation in the lungs and improves survival. The study is currently available on the bioRxiv* preprint server.

9 May 2021

Women need to avoid pregnancy for 12 months after bariatric surgery

A study presented at this year's European Congress on Obesity (held online, 10-13 May) supports recommendations to avoid pregnancy for 12 months after bariatric (obesity) surgery due to an association with adverse outcomes in pregnancy including an elevated risk of preterm birth.

8 May 2021

Complementary medicines for weight loss cannot be justified based on current evidence, review suggests

The first global review of complementary medicines (herbal and dietary supplements) for weight loss in 16 years--combining 121 randomized placebo-controlled trials including nearly 10,000 adults--suggests that their use cannot be justified based on the current evidence.

8 May 2021

Study provides new insight on how HER2-low tumors may evolve in breast cancer patients

The finding that breast tumors can evolve to express low HER2 potentially widens the number of patients who can benefit from new investigational agents, typically novel antibody-drug conjugate therapies, that are currently in clinical trials for HER2-low tumors.

8 May 2021

Unique infectious profile explains why it is so hard to treat COVID-19

A comprehensive review into what we know about COVID-19 and the way it functions suggests the virus has a unique infectious profile, which explains why it can be so hard to treat and why some people experience so-called "long-COVID", struggling with significant health issues months after infection.

7 May 2021

WVU study examines the effects of vaping during pregnancy

Spurred by unproven assumptions that vaping is safer than smoking cigarettes, a team at West Virginia University is conducting a three-year study on the effects of vaping during pregnancy.

7 May 2021

New low cost, non-electric warmer effectively treats infant hypothermia

Neonatal hypothermia -- which occurs when an infant's core body temperature falls below the normal range needed to maintain health -- contributes to approximately one million deaths each year, and countless cases of stunted growth, almost exclusively in low- and middle-income countries.

7 May 2021

Targeted therapies could exploit unique metabolic features of pancreatic cancer cells

Probing the unique biology of human pancreatic cancer cells in a laboratory has yielded unexpected insights of a weakness that can be used against the cells to kill them.

7 May 2021

New research lays the groundwork for an effective salmonella vaccine

With the COVID-19 vaccines on many people's minds, some may be surprised to learn that we do not yet have vaccines for many common infectious diseases.

7 May 2021

Medicine News and Research

Blocking fat-busting enzyme with a drug compromises cardiac repair during acute heart failure

Point-of-care ultrasonography can improve the correctness of diagnosis in patients with acute dyspnea

Esophageal cancers turn on ancient viral DNA hidden in our genome

New technique can help to non-invasively assess progression of sickle cell retinopathy

Korea's first large-scale project reaches milestone of sequencing 10,000 whole genomes

Cardiovascular risk factors accumulated from childhood linked to poorer brain function at midlife

Scientists produce a universal flu vaccine using nanoparticles to induce long-lasting immunity

Cardiac complications found to be rare in college athletes who contracted COVID-19

Total COVID-19 deaths could be 7 million

New "molecular tweezers" can help combat antibiotic-resistant bacteria

Is COVID-19 a new disease?

Researchers identify anti-inflammatory prodrug Minnelide with potential against SARS-CoV-2

Women need to avoid pregnancy for 12 months after bariatric surgery

Complementary medicines for weight loss cannot be justified based on current evidence, review suggests

Study provides new insight on how HER2-low tumors may evolve in breast cancer patients

Unique infectious profile explains why it is so hard to treat COVID-19

WVU study examines the effects of vaping during pregnancy

New low cost, non-electric warmer effectively treats infant hypothermia

Targeted therapies could exploit unique metabolic features of pancreatic cancer cells

New research lays the groundwork for an effective salmonella vaccine

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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