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Bionomics to present data from DisrupTOR-1 trial at ASCO Genitourinary Cancers Symposium

Bionomics Limited is to present important additional data from the DisrupTOR-1 trial of BNC105 in patients with metastatic renal cancer at the ASCO Genitourinary Cancers Symposium in Orlando, Florida. The data will be presented by Dr. Sumanta Pal of the City of Hope Comprehensive Cancer Center in California in his poster presentation.

28 Feb 2015

Researchers successfully convert adult human skin cells into neurons that control appetite

Researchers have for the first time successfully converted adult human skin cells into neurons of the type that regulate appetite, providing a patient-specific model for studying the neurophysiology of weight control and testing new therapies for obesity.

28 Feb 2015

Patients who undergo chemo before breast cancer operation more likely to opt for lumpectomy

Patients with larger malignant tumors of the breast who undergo chemotherapy before a breast cancer operation are more likely to opt for a breast-preserving procedure and forgo a mastectomy (surgical removal of the breast), according to a new study published online as an "article in press" in the Journal of the American College of Surgeons.

28 Feb 2015

Neuroprotective compounds can limit damage to the brain during ischemic stroke

In the 1990s, neuroscientists identified a class of drugs that showed promise in the area of stroke. NMDA receptor antagonists could limit damage to the brain in animal models of stroke. But one problem complicated testing the drugs in a clinical setting: the side effects included disorientation and hallucinations.

28 Feb 2015

New pharmacological compounds block nerve cell damage in mouse models of MS

A newly characterized group of pharmacological compounds block both the inflammation and nerve cell damage seen in mouse models of multiple sclerosis, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published online this week in the journal Nature Neuroscience.

28 Feb 2015

WHO: 1.1 billion young people at risk of hearing loss due to unsafe use of personal audio devices

Some 1.1 billion teenagers and young adults are at risk of hearing loss due to the unsafe use of personal audio devices, including smartphones, and exposure to damaging levels of sound at noisy entertainment venues such as nightclubs, bars and sporting events, according to WHO. Hearing loss has potentially devastating consequences for physical and mental health, education and employment.

27 Feb 2015

Perceived cost affects placebo response in Parkinson’s disease

Patients with Parkinson’s disease may gain a greater benefit from a placebo treatment if they believe it to be expensive, research suggests.

27 Feb 2015

New test can predict survival chances of women with breast cancer

Scientists have developed a new test which can predict the survival chances of women with breast cancer by analysing images of 'hotspots' where there has been a fierce immune reaction to a tumour.

27 Feb 2015

Chiasma closes $70 million Series E financing round

Chiasma, Inc., a U.S. privately-held biopharma company developing octreotide capsules, its lead product for the orphan condition acromegaly, today announced the closing of a $70 million Series E financing round.

27 Feb 2015

Study shows efficacy of YONDELIS (trabectedin) in patients with soft-tissue sarcoma

PharmaMar announced that the European Journal of Cancer published online data from a large retrospective study with soft-tissue sarcoma (STS) patients carried out at 25 French centers confirming that in routine practice YONDELIS (trabectedin) shows comparable or better clinical outcomes than those observed in clinical trials.

27 Feb 2015

Study shows physical similarities, differences between extrovert types in the brain

Everyday experience and psychological studies alike tell us that there are two different types of extroverts: The gregarious "people-persons" who find reward in sharing affection and affiliation with others, and the ambitious "go-getters" who flash those bright-white smiles in their pursuit of achievement and leadership agendas.

27 Feb 2015

Single-step fermentative method may facilitate industrial-scale statin drug production

University of Manchester researchers, together with industrial partner DSM, have developed a single-step fermentative method for the production of leading cholesterol-lowering drug, pravastatin, which will facilitate industrial-scale statin drug production.

27 Feb 2015

UC San Diego Health System's Movement Disorder Center joins NPF Center of Excellence network

The Movement Disorder Center at UC San Diego Health System has been designated the 41st Center of Excellence in the National Parkinson Foundation's global network. This designation is the highest recognition offered by NPF to a Parkinson's specialty clinic. It represents the consensus of leaders in the field that the UC San Diego program is among the world's leading centers for Parkinson's research, outreach and care.

27 Feb 2015

Study focuses on improving therapeutic outcomes in cancer patients through diet-drug combination

Boosting anti-cancer immunity through diet and novel drug therapies—that's the idea behind a collaborative project involving researchers from the South Dakota State University College of Pharmacy and Sanford Research in Sioux Falls.

27 Feb 2015

Study suggests benefits of calorie restriction on healthy aging

Targeting mechanisms in the central nervous system that sense energy generated by nutrients might yield the beneficial effects of low-calorie diets on healthy aging without the need to alter food intake, suggests new research from Harvard T.H. Chan School of Public Health.

27 Feb 2015

Study suggests that strong beliefs can treat nicotine addiction

Two identical cigarettes led to a discovery by scientists at the Virginia Tech Carilion Research Institute. Study participants inhaled nicotine, yet they showed significantly different brain activity. Why the difference? Some subjects were told their cigarettes were nicotine free.

27 Feb 2015

Genomics researchers discover novel gene variants in childhood CVID

Genomics researchers analyzing a rare, serious immunodeficiency disease in children have discovered links to a gene crucial to the body's defense against infections. The finding may represent an inviting target for drugs to treat common variable immunodeficiency (CVID).

27 Feb 2015

MIT researchers devise new way to make complex emulsions

MIT researchers have devised a new way to make complex liquid mixtures, known as emulsions, that could have many applications in drug delivery, sensing, cleaning up pollutants, and performing chemical reactions.

27 Feb 2015

Targeting stroma could potentially extend survival of pancreatic cancer patients

Like a stealth jet cloaks itself from radar, cancer cells cloak themselves within tumors by hiding behind a dense layer of cellular material known as stroma.

27 Feb 2015

New cancer drug enters phase I clinical trials in humans

A new drug that prompts cancer cells to self-destruct while sparing healthy cells is now entering phase I clinical trials in humans. The drug, called PAC-1, first showed promise in the treatment of pet dogs with spontaneously occurring cancers, and is still in clinical trials in dogs with osteosarcoma.

27 Feb 2015

Drugs News and Research

Bionomics to present data from DisrupTOR-1 trial at ASCO Genitourinary Cancers Symposium

Researchers successfully convert adult human skin cells into neurons that control appetite

Patients who undergo chemo before breast cancer operation more likely to opt for lumpectomy

Neuroprotective compounds can limit damage to the brain during ischemic stroke

New pharmacological compounds block nerve cell damage in mouse models of MS

WHO: 1.1 billion young people at risk of hearing loss due to unsafe use of personal audio devices

Perceived cost affects placebo response in Parkinson’s disease

New test can predict survival chances of women with breast cancer

Chiasma closes $70 million Series E financing round

Study shows efficacy of YONDELIS (trabectedin) in patients with soft-tissue sarcoma

Study shows physical similarities, differences between extrovert types in the brain

Single-step fermentative method may facilitate industrial-scale statin drug production

UC San Diego Health System's Movement Disorder Center joins NPF Center of Excellence network

Study focuses on improving therapeutic outcomes in cancer patients through diet-drug combination

Study suggests benefits of calorie restriction on healthy aging

Study suggests that strong beliefs can treat nicotine addiction

Genomics researchers discover novel gene variants in childhood CVID

MIT researchers devise new way to make complex emulsions

Targeting stroma could potentially extend survival of pancreatic cancer patients

New cancer drug enters phase I clinical trials in humans

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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