Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Healthy, cancer, and immunosuppressed patients all benefit from COVID boosters

In a recent study posted to the medRxiv* pre-print server, researchers developed a mechanistic mathematical model to predict the course of vaccine-induced immunity in healthy and immunosuppressed patients for the long term, exceeding the time frames for which clinical data is currently available.

5 Jul 2022

Novel inhalable COVID-19 vaccine

A recent study published in the Nature Biomedical Engineering journal illustrated a novel inhalable SARS-CoV-2 vaccine candidate centered on exosomes (Exos) coupled with recombinant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain (RBD).

5 Jul 2022

Scientists uncover HIV’s sweet spot

HIV researchers have long been trying to identify the specific cells that the virus prefers to infect and hide in. They know that HIV favors a special type of immune cells called memory CD4 T cells.

5 Jul 2022

Latest omicron subvariants are better at eluding vaccines and antibody treatments

The latest omicron subvariants - including the BA.4 and BA.5 forms causing new surges in infections in the United States - are even better at eluding vaccines and most antibody treatments than previous variants, finds a study by researchers at Columbia University Vagelos College of Physicians and Surgeons.

5 Jul 2022

Immune response triggered by COVID-19 damages the brain's blood vessels to cause neurological complications

A study from the National Institutes of Health describes the immune response triggered by COVID-19 infection that damages the brain's blood vessels and may lead to short- and long-term neurological symptoms.

5 Jul 2022

Study results underscore the challenges in treating interstitial pneumonia with autoimmune features

Interstitial pneumonia with autoimmune features (IPAF) is a disease with many possible causes and no standard of care, making it particularly difficult to treat.

5 Jul 2022

Next-generation SARS-CoV-2 nucleocapsid-based vaccines may provide optimal protection against infection

In a new study,researchers suggested the inclusion of nucleocapsid protein in vaccines against SARS-CoV-2.

5 Jul 2022

Deep RNA sequencing with molecular dynamic simulations can detect neutralizing antibodies elicited by COVID-19 patients

In a new study, researchers reported on the non-ACE2 blocking neutralizing antibodies elicited in response to severe coronavirus disease 2019 using deep ribonucleic acid sequencing with >100 million reads per sample and molecular dynamic simulations.

5 Jul 2022

How Pfizer won the pandemic, reaping outsize profit and influence

The grinding two-plus years of the pandemic have yielded outsize benefits for one company — Pfizer — making it both highly influential and hugely profitable as covid-19 continues to infect tens of thousands of people and kill hundreds each day.

5 Jul 2022

The influence of immunosuppressive therapy on the development of adaptive immunity after SARS-CoV-2 vaccination

Researchers evaluated the impact of immunosuppressive therapies on the induction of adaptive immunity after COVID-19 vaccination.

5 Jul 2022

Patient-derived antibody cocktail active across SARS-CoV-2 variants of concern

In a recent study published in the journal Science Immunology, researchers in the United States described a rare anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) three antibody cocktail IMM-BCP-01.

4 Jul 2022

Most therapeutic antibodies for treating COVID-19 patients do not inhibit emerging Omicron subvariants

The Omicron subvariants BA.1 and BA.2 of SARS-CoV-2 have dominated the COVID-19 pandemic in early 2022. In many countries, these viruses are now outcompeted by emerging subvariants, with BA.5 being responsible for the current uptick of cases in Germany.

1 Jul 2022

New antibody-based method for SARS-CoV-2 detection does not require a blood sample

Despite significant and stunning advances in vaccine technology, the COVID-19 global pandemic is not over. A key challenge in limiting the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is identifying infected individuals.

1 Jul 2022

Scientists develop antibody test to keep track of immunity to SARS-CoV-2 variants

The experts agree - the pandemic is not over. Infections are ticking up again, fueled by the new variants our immune systems are ill prepared for.

1 Jul 2022

Somatic hypermutations found to enhance humoral immunity against SARS-CoV-2 variants

Researchers explored the molecular basis for increased immunity against heterologous SARS-CoV-2 strains after repeated antigen exposures.

1 Jul 2022

Study evaluates if adults with obesity and a history of SARS-CoV-2 infection demonstrate poorer T cell immunity

Researchers assessed the association between obesity and T cell frequencies specific to the SARS-CoV-2 antigen.

1 Jul 2022

The impact of pre-existing immunity on mRNA booster doses of BNT162b2 and mRNA-1273 vaccines against SARS-CoV-2

Researchers assessed the impact of pre-existing immunity on mRNA booster doses of BNT162b2 and mRNA-1273 vaccines against SARS-CoV-2.

1 Jul 2022

Mosaic-8 RBD-nanoparticles show promise against current and future SARS-CoV-2 variants

A recent study posted to the bioRxiv* preprint server supports using mosaic sarbecovirus receptor-binding domain (RBD)-nanoparticles to discover therapeutic pan-variant and pan-sarbecovirus monoclonal antibodies (mAbs) and to induce mAbs by vaccination.

30 Jun 2022

How to develop an "all-variant" COVID vaccine

In a recent study published in Nature Immunology, researchers summarized their observations of humoral immune responses elicited in severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infected people. Additionally, they discussed all the types of SARS-CoV-2 infection- and vaccine-induced neutralizing antibodies (nAbs).

30 Jun 2022

Casirivimab/imdevimab improve outcomes in early COVID-19

A new Viruses study determines the effect of casirivimab/imdevimab on IFN-1 and cytokines during SARS-CoV-2 infection.

29 Jun 2022

Antibody News and Research

Further Reading

Healthy, cancer, and immunosuppressed patients all benefit from COVID boosters

Novel inhalable COVID-19 vaccine

Scientists uncover HIV’s sweet spot

Latest omicron subvariants are better at eluding vaccines and antibody treatments

Immune response triggered by COVID-19 damages the brain's blood vessels to cause neurological complications

Study results underscore the challenges in treating interstitial pneumonia with autoimmune features

Next-generation SARS-CoV-2 nucleocapsid-based vaccines may provide optimal protection against infection

Deep RNA sequencing with molecular dynamic simulations can detect neutralizing antibodies elicited by COVID-19 patients

How Pfizer won the pandemic, reaping outsize profit and influence

The influence of immunosuppressive therapy on the development of adaptive immunity after SARS-CoV-2 vaccination

Patient-derived antibody cocktail active across SARS-CoV-2 variants of concern

Most therapeutic antibodies for treating COVID-19 patients do not inhibit emerging Omicron subvariants

New antibody-based method for SARS-CoV-2 detection does not require a blood sample

Scientists develop antibody test to keep track of immunity to SARS-CoV-2 variants

Somatic hypermutations found to enhance humoral immunity against SARS-CoV-2 variants

Study evaluates if adults with obesity and a history of SARS-CoV-2 infection demonstrate poorer T cell immunity

The impact of pre-existing immunity on mRNA booster doses of BNT162b2 and mRNA-1273 vaccines against SARS-CoV-2

Mosaic-8 RBD-nanoparticles show promise against current and future SARS-CoV-2 variants

How to develop an "all-variant" COVID vaccine

Casirivimab/imdevimab improve outcomes in early COVID-19

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