Cancer Therapy News and Research

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Oncofertility complications reviewed for US patients

Three articles published in JAMA Oncology highlight the legal and clinical care issues surrounding fertility preservation in US patients with cancer.

4 Feb 2016

New drug cocktail may show promise in NSCLC patients

A drug approved by the Food and Drug Administration for melanoma in combination with a common cholesterol-lowering drug may show promise in controlling cancer growth in patients with non-small cell lung cancer (NSCLC), according to new research from the Icahn School of Medicine at Mount Sinai.

3 Feb 2016

Genetic profiling ‘feasible’ for paediatric cancer patients

Research published in JAMA Oncology demonstrates that tumour and germline molecular profiling is feasible in paediatric cancer patients and can have actionable findings.

2 Feb 2016

Study provides vital information about mechanisms governing DNA repair

DNA damage can lead to gene inactivation or deregulation and cause various diseases such as cancer; however, many DNA repair mechanisms allow cells to survive against such damage. A study lead by Antoine Simoneau of the laboratory of Dr. Hugo Wurtele, a researcher in immunology-oncology at the Maisonneuve-Rosemont Hospital (CIUSS de l'Est-de-l'Île-de-Montréal) and professor at the Faculty of Medicine, University of Montreal, and recently published in the prestigious journal Nucleic Acids Research, provides valuable information about certain mechanisms governing DNA repair.

31 Jan 2016

TSRI scientists reveal workings of key 'relief-valve' in cells

A team led by scientists at The Scripps Research Institute has solved a long-standing mystery in cell biology by showing essentially how a key "relief-valve" in cells does its job.

30 Jan 2016

Mistrust toward cancer treatment and health care system persists among African Americans

Mistrust toward breast cancer treatment and the health care system at large were expressed by African Americans who participated in Chicago focus groups, suggests new research led by an expert on the health of vulnerable populations at the Brown School at Washington University in St. Louis.

29 Jan 2016

Quest Diagnostics to offer in vitro diagnostic test for use in detection of PD-L1 expression for melanoma

Quest Diagnostics, the world’s leading provider of diagnostic information services, today announced it will offer clinical laboratory testing using the PD-L1 IHC 28-8 pharmDx qualitative test from Dako, an Agilent Technologies company.

From Quest Diagnostics 27 Jan 2016

The mechanism behind protective cells protecting themselves

Researchers at St. Jude Children's Research Hospital have discovered the mechanism by which immune cells called regulatory T cells keep themselves intact and functional during their demanding task of holding the immune system in check. Such T cells are key to preventing the immune system from attacking the body in autoimmune disease.

26 Jan 2016

UT Southwestern researchers reveal how CDK4/6-inhibitors alter pancreatic cancer cell metabolism

UT Southwestern Medical Center researchers have found that cancer drugs known as CDK4/6-inhibitors alter the metabolism of pancreatic cancer cells, revealing a biologic vulnerability that could be exploited for therapeutic gain.

22 Jan 2016

Paradigm, UnitedHealthcare sign contractual agreement for coverage of PCDx

Paradigm, a molecular information & Next Generation Sequencing corporation specializing in providing testing for cancer patients today announced that it has entered into a contractual agreement with UnitedHealthcare for coverage of PCDx.

21 Jan 2016

Amorphous iron nanoparticles have potential to kill tumor cells

Amorphous iron nanoparticles have a specific toxicity in tumor cells. In the journal Angewandte Chemie, Chinese scientists describe their design and synthesis of a special amorphous state of nanoparticulate iron, which can locally release reactive iron species in the acidic and hydrogen peroxide rich environment of cancer cells, providing new possibilities for theranostics and chemodynamic therapies.

20 Jan 2016

Diabetes drug fails to show any benefit against pancreatic cancer

A diabetes drug that showed promise in previous studies as an anti-cancer treatment failed to show any benefit in a UNC Lineberger Comprehensive Cancer Center-led study that used pancreatic cancer tissue samples to test sensitivity to the drug.

20 Jan 2016

Experts create new guidelines to improve treatments for cancer patients

A committee of national experts, led by a Cleveland Clinic researcher, has established first-of-its-kind guidelines to promote more accurate and individualized cancer predictions, guiding more precise treatment and leading to improved patient survival rates and outcomes.

20 Jan 2016

Combining nanomedicine with two anticancer treatments could improve outcomes for pancreatic cancer patients

A nanoparticle drug-delivery system that combines two complementary types of anticancer treatment could improve outcomes for patients with pancreatic cancer and other highly treatment-resistant tumors while decreasing toxicity.

20 Jan 2016

Four USF professors selected as AIMBE College of Fellows

Four University of South Florida professors have been elected to the 2016 College of Fellows of the American Institute for Medical and Biological Engineering (AIMBE): Cesario Borlongan and Shyam Mohapatra from the USF Morsani College of Medicine, USF Health; and Robert Frisina, Jr., and Sudeep Sarkar from the USF College of Engineering.

20 Jan 2016

Needle-free administration of anesthetic in the mouth could save costs, improve patient compliance

If you're scared of the dentist's needles you're not alone - but new research means you might not have to put off that appointment again. A study published in Colloids and Surfaces B: Biointerfaces reveals how the dentist could give you anesthetic using a tiny electric current instead of a needle.

19 Jan 2016

NSCLC treatments market in Europe expected to cross US$ 3 billion by 2019

According to recently published Pharmaion report, "Europe Non-Small Cell Lung Cancer Treatments Market Opportunities, 2010 - 2020", the non-small cell lung cancer (NSCLC) treatments market in Europe is anticipated to cross US$ 3 billion by 2019.

18 Jan 2016

UM SOM selected to work with BARDA to develop radiologic and nuclear countermeasures

University of Maryland School of Medicine Department of Radiation Oncology Chair and Professor William F. Regine, MD, FACR, FACRO, and UM SOM Dean E. Albert Reece, MD, PhD, MBA, announced today that researchers at the UM SOM have been selected as key contractors by the Biomedical Advanced Research and Development Authority, for its Radiation Nuclear Animal Model Development program.

18 Jan 2016

Scientists find new way to re-engineer body’s immune system to target cancer

Scientists have demonstrated a new way of re-engineering the body’s immune system to target cancer, paving the way for a new generation of drugs, unprecedented in safety and effectiveness.

18 Jan 2016

New studies provide insights into impact of vision loss among survivors of childhood cancers

Little is known about the long-term health of survivors of childhood cancers that affect vision, but two new studies provide valuable insights that could impact patient care and follow-up. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

12 Jan 2016

Cancer Therapy News and Research

Oncofertility complications reviewed for US patients

New drug cocktail may show promise in NSCLC patients

Genetic profiling ‘feasible’ for paediatric cancer patients

Study provides vital information about mechanisms governing DNA repair

TSRI scientists reveal workings of key 'relief-valve' in cells

Mistrust toward cancer treatment and health care system persists among African Americans

Quest Diagnostics to offer in vitro diagnostic test for use in detection of PD-L1 expression for melanoma

The mechanism behind protective cells protecting themselves

UT Southwestern researchers reveal how CDK4/6-inhibitors alter pancreatic cancer cell metabolism

Paradigm, UnitedHealthcare sign contractual agreement for coverage of PCDx

Amorphous iron nanoparticles have potential to kill tumor cells

Diabetes drug fails to show any benefit against pancreatic cancer

Experts create new guidelines to improve treatments for cancer patients

Combining nanomedicine with two anticancer treatments could improve outcomes for pancreatic cancer patients

Four USF professors selected as AIMBE College of Fellows

Needle-free administration of anesthetic in the mouth could save costs, improve patient compliance

NSCLC treatments market in Europe expected to cross US$ 3 billion by 2019

UM SOM selected to work with BARDA to develop radiologic and nuclear countermeasures

Scientists find new way to re-engineer body’s immune system to target cancer

New studies provide insights into impact of vision loss among survivors of childhood cancers

Event guide: 7th Allogeneic Cell Therapies Summit eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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