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Medication holds promise for protecting fertility and the body's defense system during chemotherapy

While targeted cancer treatments have reduced side effects and improved efficacy, chemotherapy remains the backbone of combination therapies for many forms of cancer. Unfortunately, cancer patients may suffer from several side effects from chemotherapy, including infertility and a weakened defense system that makes them susceptible to life-threatening infections.

15 Dec 2015

BD announces launch of BD FACSCelesta flow cytometer during ASCB annual meeting

BD (Becton, Dickinson and Company), a leading global medical technology company, today announced the launch of the BD FACSCelesta flow cytometer during the 2015 American Society for Cell Biology annual meeting. Uniquely designed to leverage the broad BD Horizon Brilliant reagent portfolio, this new system offers simultaneous measurement of up to 14 different single cell characteristics.

13 Dec 2015

CRISPR/Cas9 turns hPSCs into cell-based lab model system for polycystic kidney disease

CRISPR/Cas9 is hot. News of the revolutionary gene editing technique that is already shaking up bioscience has finally reached the news media and the public. Now comes a first rate example of how CRISPR is changing the pace of biomedical research by linking up with another cutting edge technology -- human pluripotent stem cells (hPSCs).

12 Dec 2015

CRISPR-Cas9 can help knock out genes in exotic animals

The simplicity of CRISPR-Cas9 gene editing will soon make studying the genes of any organism, from the simplest slime mold to the octopus, as easy as it now is to study the genes controlling development in standard lab animals such as nematodes, fruit flies, frogs and mice.

12 Dec 2015

Researchers use endocytic pathways to sort out NSCLC lines into two distinct clusters

In the Age of Personalized Medicine, we've learned that one size doesn't fit all, least of all in cancer. Cancer is a disease of your cells, and sorting out your cancer from all others is a daunting challenge but one that cancer cell biologists are furiously pursuing. They are examining every aspect of cell function and cell structure, looking for clusters of phenotypes that could label a patient's cancer so precisely that it could be linked to therapies proven effective against just that type.

12 Dec 2015

Mount Sinai scientists develop new tool to determine global role of microRNAs

As microRNA biology has been implicated in everything from the development of cancer to virus infections, a new tool developed by scientists at the Icahn School of Medicine at Mount Sinai holds tremendous potential to develop new therapies that involve these small regulatory fragments of RNA.

11 Dec 2015

UB researchers develop a way to ramp up conversion of skin cells into dopamine neurons

For decades, the elusive holy grail in Parkinson's disease research has been finding a way to repair faulty dopamine neurons and put them back into patients, where they will start producing dopamine again. Researchers have used fetal material, which is difficult to obtain and of variable quality. Embryonic stem cells represented a tremendous innovation, but making dopamine neurons from stem cells is a long process with a low yield.

8 Dec 2015

Researchers find new significant link between NPM protein and development of AML

A team of researchers from the National University of Singapore has found a new significant correlation between the protein nucleophosmin (NPM) and the development of an aggressive form of blood cancer called acute myeloid leukemia (AML).

8 Dec 2015

Excellence in graduate student research, third annual Kaluza prizes

Beckman Coulter collaborated with the American Society for Cell Biology to sponsor the Third Annual ASCB Kaluza Prizes for academic excellence.

From Beckman Coulter Life Sciences - Flow Cytometry 7 Dec 2015

The Importance of Flexibility in Spectrophotometry

News-Medical speaks to Jessica Geisler about the need for flexible spectrophotometers that can handle a range of measurement types.

From Eppendorf 1 Dec 2015

Scientists show how malaria parasites invade the liver

Scientists at the Center for Infectious Disease Research recently uncovered a critical piece in the puzzle of how malaria parasites infect their host. The work, recently published in Science Magazine, reveals the details of how the malaria parasite invades its initial target organ, the liver. Without infection of the liver, the parasites cannot multiply or spread to the blood. Infection of the blood causes illness, spread of the disease, and, ultimately, death.

27 Nov 2015

Scientists create detailed image of deadly toxin linked to bacterial pneumonia, meningitis, septicaemia

Scientists from the University of Leicester have for the first time created a detailed image of a toxin - called pneumolysin - associated with deadly infections such as bacterial pneumonia, meningitis and septicaemia.

25 Nov 2015

Researchers reveal causal association between aneuploidy and cancer

Publication in Nature Cell Biology: researchers at the Université libre de Bruxelles - ULB Cancer Research Center, U-CRC - show the causal link between aneuploidy and cancer.

24 Nov 2015

New study finds evidence to support meperidine-associated seizure risk

Meperidine, an opioid analgesic commonly used to control shivering in accidental or therapeutic hypothermia, has been linked to increased seizure risk, but a new study finds little published evidence to support this risk.

24 Nov 2015

Researchers suggest new way to target cancer protein

For years, scientists have struggled to find a way to block a protein known to play an important role in many cancers. The protein, STAT3, acts as a transcription factor -- it performs the crucial task of helping convert DNA into the RNA instructions used to make new proteins.

19 Nov 2015

RNA-based drugs provide many advantages over CRISPR/Cas9 gene editing system

In just the past few years, researchers have found a way to use a naturally occurring bacterial system known as CRISPR/Cas9 to inactivate or correct specific genes in any organism. CRISPR/Cas9 gene editing activity runs continuously, though, leading to risk of additional editing at unwanted sites. Now, researchers at University of California, San Diego School of Medicine, Ludwig Cancer Research and Isis Pharmaceuticals demonstrate a commercially feasible way to use RNA to turn the CRISPR-Cas9 system on and off as desired -- permanently editing a gene, but only temporarily activating CRISPR-Cas9.

17 Nov 2015

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life. Metabolites are simple compounds generated during life-sustaining chemical activities in cells.

17 Nov 2015

MedUni Vienna researchers discover genetic cause of a rare disease

Researchers at MedUni Vienna have discovered the genetic cause of a rare disease characterized by life-threatening "liver crises" in early childhood and subsequent manifestation of neurological symptoms, such as neuropathy and ataxia (a movement disorder), when they reach school age.

15 Nov 2015

New research examines previously unknown secret to DNA repair

Michael Hendzel knows all too well that there is little that people can do to control the stability of their genetic code. But he hopes his latest research will help impact this elusive and crucial aspect of medicine. Published in Nature Cell Biology, this research explores a previously unknown secret to DNA repair.

12 Nov 2015

First comprehensive genomic and biologic study of top skin disease-causing microbes

An international team of scientists, led by researchers from A*STAR's Genome Institute of Singapore (GIS), Institute of Medical Biology (IMB), and Bioinformatics Institute (BII), and P&G, have completed the first comprehensive genomic and biologic study of all species of Malassezia, one of the top skin disease-causing microbes.

9 Nov 2015

Cell Biology News and Research

Medication holds promise for protecting fertility and the body's defense system during chemotherapy

BD announces launch of BD FACSCelesta flow cytometer during ASCB annual meeting

CRISPR/Cas9 turns hPSCs into cell-based lab model system for polycystic kidney disease

CRISPR-Cas9 can help knock out genes in exotic animals

Researchers use endocytic pathways to sort out NSCLC lines into two distinct clusters

Mount Sinai scientists develop new tool to determine global role of microRNAs

UB researchers develop a way to ramp up conversion of skin cells into dopamine neurons

Researchers find new significant link between NPM protein and development of AML

Excellence in graduate student research, third annual Kaluza prizes

The Importance of Flexibility in Spectrophotometry

Scientists show how malaria parasites invade the liver

Scientists create detailed image of deadly toxin linked to bacterial pneumonia, meningitis, septicaemia

Researchers reveal causal association between aneuploidy and cancer

New study finds evidence to support meperidine-associated seizure risk

Researchers suggest new way to target cancer protein

RNA-based drugs provide many advantages over CRISPR/Cas9 gene editing system

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

MedUni Vienna researchers discover genetic cause of a rare disease

New research examines previously unknown secret to DNA repair

First comprehensive genomic and biologic study of top skin disease-causing microbes

Cutting-edge advances in biomedical imaging and analysis eBook eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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