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Adult stem cell changes underlie Hutchinson-Gilford Progeria syndrome associated with accelerated aging

Adult stem cells may provide an explanation for the cause of a Hutchinson-Gilford Progeria Syndrome (HGPS), a rare disease that causes premature aging in children, according to researchers at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH).

3 Mar 2008

Ciliary neurotrophic factor protects nerve cells

Since its discovery as a protein that gets specifically released in response to brain injury, ciliary neurotrophic factor (CNTF) has prompted much interest as a potential therapeutic agent.

1 Mar 2008

Brain differences between women and men

What was once speculation is now being confirmed by scientists: the brains of women and men are different in more ways than one.

1 Mar 2008

New global study of targeted therapies for breast cancer

Two targeted medications designed to treat an aggressive form of breast cancer are being tested in a new study involving 8,000 participants in 50 countries across six continents -- a clinical trial that investigators hope will provide a new model for global cancer research.

1 Mar 2008

Discovery of gene in Asian monkeys that blocks AIDS

Researchers at Harvard Medical School have identified a gene in Asian monkeys that may have evolved as a defense against lentiviruses, the group of viruses that includes HIV.

1 Mar 2008

Genetic factors in smoking also increase risk of chronic bronchitis

Smoking is a known risk factor for respiratory diseases like chronic bronchitis, but genes also play a significant role in its development, according to researchers in Sweden, who studied more than 40,000 Swedish twins to determine the extent to which behavior, environment and genes each play a role ion the development of chronic bronchitis.

1 Mar 2008

Zebrafish help understand hearing loss

A small striped fish is helping scientists understand what makes people susceptible to a common form of hearing loss, although, in this case, it's not the fish's ears that are of interest.

1 Mar 2008

Potential target to treat deadly bloodstream infections

Researchers at the University of Illinois at Chicago have discovered a possible target to treat bloodstream bacterial infections.

28 Feb 2008

New genetic link to schizophrenia

Schizophrenia emerges from an altered pattern of brain development, and researchers continue to search for the genes that cause the brain to develop along a path that ultimately leads to schizophrenia.

28 Feb 2008

Using microorganisms to remove trichloroethene from water

In 2002, Bruce Rittmann, PhD, director of the Biodesign Institute's Center for Environmental Biotechnology, received a patent for an innovative way to use nature to lend society a hand.

28 Feb 2008

Gene expression differences between Europeans and Africans affect response to drugs, infections

Differences in gene expression levels between people of European versus African ancestry can affect how each group responds to certain drugs or fights off specific infections, report researchers from the University of Chicago Medical Center and the Expression Research Laboratory at Affymetrix Inc. of Santa Clara, CA.

28 Feb 2008

Discovery of family of genes linked to the development of liver cancer

An interdisciplinary team of researchers at Stony Brook University Medical Center has identified a family of genes linked to the development of liver cancer.

28 Feb 2008

New drug trial to target hereditary cancers

Cancer Research UK scientists at Newcastle University are starting the first UK trial of a new drug which targets the 'Achilles' heel' in hereditary forms of both breast and ovarian cancer.

28 Feb 2008

New drug trial to target hereditary cancers

Cancer Research UK scientists at Newcastle University are starting the first UK trial of a new drug which targets the 'Achilles' heel' in hereditary forms of both breast and ovarian cancer.

28 Feb 2008

Inverted DNA turns quiet developmental gene into a potent driver of t-cell lymphoma

A gene crucial for embryonic development can quickly become a potent cancer promoter in adult mice after a genetic misalignment, according to researchers from Fox Chase Cancer Center, causing white blood cells to become cancerous spontaneously.

28 Feb 2008

URMC cardiac team celebrates 100th heart transplant

The Program in Heart Failure and Transplantation at the University of Rochester Medical Center has reached a milestone, performing its 100th cardiac transplant surgery.

27 Feb 2008

Protein that stimulates blood vessel growth worsens ovarian cancer

A protein that stimulates blood vessel growth worsens ovarian cancer, but its production can be stifled by a tiny bit of RNA wrapped in a fatty nanoparticle, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the Journal of the National Cancer Institute.

27 Feb 2008