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Georgia State signs license agreement with Cisen to develop compounds for treating cancer

Georgia State University has signed a license agreement with Cisen Pharmaceutical Co. Ltd., a comprehensive pharmaceutical enterprise in China, to develop cancer-fighting compounds designed by Georgia State researcher Dr. Binghe Wang, in collaboration with Professor Muxiang Zhou of Emory University, a cancer biologist.

20 Feb 2015

New study turns to epigenetics to look for new therapeutic targets to treat allergic diseases

Scientists have discovered over 30 new genes that predispose people to allergies and asthma, some of which could be targets for new drugs.

20 Feb 2015

Scientists identify promising new therapeutic target for prostate cancer

Keck Medicine of the University of Southern California scientists have found a promising new therapeutic target for prostate cancer. The findings offer evidence that a newly discovered member of a family of cell surface proteins called G-protein coupled receptors (GPCRs) promotes prostate cancer cell growth. The protein, GPR158, was found while the researchers were looking for new drug targets for glaucoma.

20 Feb 2015

Study helps solve mystery about how genetic variations can increase cancer risk

Single-letter genetic variations within parts of the genome once dismissed as 'junk DNA' can increase cancer risk through wormhole-like effects on far-off genes, new research shows.

19 Feb 2015

IDRI Announces $4M BARDA Cooperative Agreement To Establish Adjuvant Hub

The international outbreak of Ebola in 2014 serves as a reminder for the need to be proactive in preparing for the rapid spread of any newly emerging or re-emerging infectious disease. IDRI today announces it has received $4 million in funding from the Biomedical Advanced Research and Development Authority, part of the U.S. Department of Health and Human Services, to develop an adjuvant manufacturing hub with both preclinical and clinical expertise to facilitate pandemic influenza preparedness in developing countries.

19 Feb 2015

New doctorate program to study substance use and related social, health consequences

A new Joint Doctoral Program (JDP) in Interdisciplinary Research on Substance Use has been launched by the Division of Global Public Health in the University of California, San Diego School of Medicine and San Diego State University's School of Social Work. The program will emphasize research devoted to studying the use and misuse of alcohol and drugs - and related social and health consequences.

19 Feb 2015

New study links chicken pox and shingles virus to giant cell arteritis in elderly

A new study links the virus that causes chicken pox and shingles to a condition that inflames blood vessels on the temples and scalp in the elderly, called giant cell arteritis. The study is published in the February 18, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology. The condition can cause sudden blindness or stroke and can be life-threatening.

19 Feb 2015

International study shows potential new therapy to treat patients with neuropathic pain

An international study led by scientists at McGill University reports, for the first time, that drugs that selectively target the melatonin MT2 receptor represent a novel class of analgesic drugs that could be used to treat patients with neuropathic pain.

19 Feb 2015

Targeted nanomedicines could help prevent heart attacks caused by atherosclerosis

Nanometer-sized "drones" that deliver a special type of healing molecule to fat deposits in arteries could become a new way to prevent heart attacks caused by atherosclerosis, according to a study in pre-clinical models by scientists at Brigham and Women's Hospital and Columbia University Medical Center.

19 Feb 2015

Researchers reveal how C. difficile wreaks havoc on guts, causes life-threatening diseases

In a new paper in the journal Infection and Immunity, the researchers lay out for the first time exactly how C. difficile wreaks havoc on the guts of animals in a short time, and causes severe diarrhea and life-threatening disease in humans.

19 Feb 2015

HIV Prevention Trials Network launches two phase 2 studies to evaluate new HIV drugs

The HIV Prevention Trials Network has launched two new phase 2 studies, HPTN 076 and HPTN 077, which are designed to evaluate new drugs to protect people from getting infected with HIV.

19 Feb 2015

Research findings could someday lead to new treatments for patients with autism and cancer

In recent years, scientists have found a surprising a connection between some people with autism and certain cancer patients: They have mutations in the same gene, one that codes for a protein critical for normal cellular health. Now scientists have reported in the ACS journal Biochemistry that the defects reduce the activity and stability of the protein.

19 Feb 2015

Natalizumab drug helps scientists confirm how 'viral reservoirs' form in HIV patients

A drug used to treat patients with Crohn's disease and multiple sclerosis has helped scientists confirm how "viral reservoirs" form in patients living with HIV and also proven effective in animal trials at blocking the pathways to those reservoirs in the brain and gut, a team of researchers reported recently in the journal PLOS Pathogens.

19 Feb 2015

Doctoral students of Magicbullet network to develop 'gentle' cancer treatment

Medication that specifically targets cancer cells and delivers its active agent without harming healthy cells - this is what doctoral students of the Magicbullet network will be working on from mid-2015. Bielefeld University is coordinating the programme for the development of "gentle" cancer treatment.

19 Feb 2015

Researchers report development of first 3D tissue-engineered system

A team led by researchers at Tufts University School of Engineering and the University of Pavia has reported development of the first three-dimensional tissue system that reproduces the complex structure and physiology of human bone marrow and successfully generates functional human platelets.

19 Feb 2015

BUSM's medical education program wins HIDTA award for Outstanding Prevention Effort

White House Drug Control Policy Director Michael Botticelli has awarded Boston University School of Medicine's Safe and Competent Opioid Prescribing Education (SCOPE of Pain) program a 2014 National High Intensity Drug Trafficking Area (HIDTA) award for Outstanding Prevention Effort.

19 Feb 2015

NIH-sponsored clinical trials examine safety, acceptability of HIV antiretroviral medicines

Two new clinical trials are examining the safety and acceptability of antiretroviral medicines administered via injection as a means of protecting against HIV infection. The studies are being funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, and conducted by the NIAID-funded HIV Prevention Trials Network (HPTN).

19 Feb 2015

UT Dallas study reports new gene therapy approach

Bioengineers at The University of Texas at Dallas have created a novel gene-delivery system that shuttles a gene into a cell, but only for a temporary stay, providing a potential new gene-therapy strategy for treating disease.

19 Feb 2015

Nicotine metabolite supports learning, memory by amplifying action of primary chemical messenger

Nicotine's primary metabolite supports learning and memory by amplifying the action of a primary chemical messenger involved in both, researchers report.

19 Feb 2015

Study examines relationship between substance use and teen pregnancy

New research from The University of Texas at Austin suggests that many teenagers, especially younger teens, may not be getting the message about the risks of using alcohol and other drugs during pregnancy -- but that having involved parents and being engaged academically can help.

19 Feb 2015

Drugs News and Research

Georgia State signs license agreement with Cisen to develop compounds for treating cancer

New study turns to epigenetics to look for new therapeutic targets to treat allergic diseases

Scientists identify promising new therapeutic target for prostate cancer

Study helps solve mystery about how genetic variations can increase cancer risk

IDRI Announces $4M BARDA Cooperative Agreement To Establish Adjuvant Hub

New doctorate program to study substance use and related social, health consequences

New study links chicken pox and shingles virus to giant cell arteritis in elderly

International study shows potential new therapy to treat patients with neuropathic pain

Targeted nanomedicines could help prevent heart attacks caused by atherosclerosis

Researchers reveal how C. difficile wreaks havoc on guts, causes life-threatening diseases

HIV Prevention Trials Network launches two phase 2 studies to evaluate new HIV drugs

Research findings could someday lead to new treatments for patients with autism and cancer

Natalizumab drug helps scientists confirm how 'viral reservoirs' form in HIV patients

Doctoral students of Magicbullet network to develop 'gentle' cancer treatment

Researchers report development of first 3D tissue-engineered system

BUSM's medical education program wins HIDTA award for Outstanding Prevention Effort

NIH-sponsored clinical trials examine safety, acceptability of HIV antiretroviral medicines

UT Dallas study reports new gene therapy approach

Nicotine metabolite supports learning, memory by amplifying action of primary chemical messenger

Study examines relationship between substance use and teen pregnancy

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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