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Combined therapy approach could prove promising to treat brain cancer

A "combined therapy" approach to treating the most common form of brain cancer could prove promising, scientists say.

28 Jun 2016

Deficiency in NMD could cause inflammatory myofibroblastic tumors

Inflammatory myofibroblastic tumors (IMTs) — masses of immune cells— are benign, but poorly understood. Current IMT treatments often have side effects and surgery is sometimes not an option due to the tumor's proximity to vital organs.

28 Jun 2016

Blocking c-Abl enzyme prevents Parkinson’s disease progression in mice

Researchers at Johns Hopkins say they have gleaned two important new clues in the fight against Parkinson's disease: that blocking an enzyme called c-Abl prevents the disease in specially bred mice, and that a chemical tag on a second protein may signal the disorder's presence and progression.

28 Jun 2016

Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Appetite, as a word, come from the Latin appetitus, meaning "desire for.” Therefore, appetite can be defined as a pleasurable sensation or the desire to eat. This sensation is coordinated by several brain areas associated with reward processing such amygdala, hippocampus, ventral pallidum, nucleus accumbens and striatum, and others.

28 Jun 2016

TSRI scientists identify GlyRS protein that launches cancer growth

Scientists at The Scripps Research Institute have identified a protein that launches cancer growth and appears to contribute to higher mortality in breast cancer patients.

28 Jun 2016

Scientists explain how engineered anthrax toxin proteins could help eliminate cancerous tumors

Scientists from the National Institute of Allergy and Infectious Diseases, the National Institute of Dental and Craniofacial Research, and the National Heart, Lung and Blood Institute all parts of the National Institutes of Health, describe how combining engineered anthrax toxin proteins and existing chemotherapy drugs could potentially yield a therapy to reduce or eliminate cancerous tumors.

28 Jun 2016

Researchers test new drug with potential to reverse or slow progression of asthma

A new drug with the potential to reverse or slow the development of asthma is being tested by researchers at The University of Queensland.

28 Jun 2016

Pain reliever appears to help preserve vision in animal model of retinal degeneration

A pain medicine that potently activates a receptor vital to a healthy retina appears to help preserve vision in a model of severe retinal degeneration, scientists report.

28 Jun 2016

Food's transit time through colon affects health of digestive system

The time it takes for ingested food to travel through the human gut - also called transit time - affects the amount of harmful degradation products produced along the way.

28 Jun 2016

Study pinpoints how PSEN1 gene mutations can cause early onset Alzheimer's disease

A University of Adelaide analysis of genetic mutations which cause early-onset Alzheimer's disease suggests a new focus for research into the causes of the disease.

27 Jun 2016

Researchers tune into previously unknown cross talk between estrogen and progesterone receptors

One of the first clues pathologists look for in tissue from a newly diagnosed breast cancer patient is the estrogen receptor, a nuclear protein that converts hormonal messages in the bloodstream into instructions for the cell about how to behave

24 Jun 2016

HMC signal could be used to detect diseases and to personalize medication

Common diseases like allergy, diabetes and other immune diseases have increased dramatically in recent decades. This indicates that the environment may have a more important role than genes in explaining this increase.

24 Jun 2016

NCX1 protein could help prevent progression of heart failure

A protein known to be crucial for maintaining the balance of calcium in cells could prove useful in halting the progression of heart failure.

24 Jun 2016

Mutant fruit flies provide insight into origins of Parkinson's disease

The neurodegeneration that occurs in Parkinson’s disease is a result of stress on the endoplasmic reticulum in the cell rather than failure of the mitochondria as previously thought, according to a study in fruit flies.

24 Jun 2016

Researchers identify new potential target for pancreatic cancer treatment

Using an innovative approach to identify a cancer's genetic vulnerabilities by more swiftly analyzing human tumors transplanted into mice, researchers have identified a new potential target for pancreatic cancer treatment, published online in Cell Reports.

24 Jun 2016

New insights into cancer cell signaling could help prevent metastases

Research published yesterday in Nature Communications has revealed a previously unknown mechanism by which metastasising cancer cells survive when they break away from the primary tumour. It is hoped that the discovery could help with the development of novel cancer treatments that prevent metastasis.

24 Jun 2016

Researchers reveal integrins could be key to survival mechanism in cancer cells

Cancer cells appear to depend on an unusual survival mechanism to spread around the body, according to an early study led by Queen Mary University of London. The discovery could help with future development of novel treatments to prevent metastasis and secondary tumours.

24 Jun 2016

Scientists isolate antibodies capable of neutralizing dengue and Zika virus

Scientists from the Institut Pasteur and the CNRS, in collaboration with Imperial College London and the University of Vienna, Austria, have identified antibodies that can efficiently neutralize both the dengue virus and the Zika virus.

24 Jun 2016

Broccoli sprout extract may help prevent cancer recurrence in head and neck cancer survivors

Potent doses of broccoli sprout extract activate a "detoxification" gene and may help prevent cancer recurrence in survivors of head and neck cancer, according to a trial by the University of Pittsburgh Cancer Institute, partner with UPMC CancerCenter, confirming preliminary results presented last year at the American Association for Cancer Research Annual Meeting.

24 Jun 2016

Yale-led study shows how EGFR silences tumor suppressor genes

A Yale-led study describes how a known cancer gene, EGFR, silences genes that typically suppress tumors. The finding, published in Cell Reports, may lead to the development of more effective, individualized treatment for patients with lung cancer and other cancer types.

24 Jun 2016

G Protein News and Research

Combined therapy approach could prove promising to treat brain cancer

Deficiency in NMD could cause inflammatory myofibroblastic tumors

Blocking c-Abl enzyme prevents Parkinson’s disease progression in mice

Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

TSRI scientists identify GlyRS protein that launches cancer growth

Scientists explain how engineered anthrax toxin proteins could help eliminate cancerous tumors

Researchers test new drug with potential to reverse or slow progression of asthma

Pain reliever appears to help preserve vision in animal model of retinal degeneration

Food's transit time through colon affects health of digestive system

Study pinpoints how PSEN1 gene mutations can cause early onset Alzheimer's disease

Researchers tune into previously unknown cross talk between estrogen and progesterone receptors

HMC signal could be used to detect diseases and to personalize medication

NCX1 protein could help prevent progression of heart failure

Mutant fruit flies provide insight into origins of Parkinson's disease

Researchers identify new potential target for pancreatic cancer treatment

New insights into cancer cell signaling could help prevent metastases

Researchers reveal integrins could be key to survival mechanism in cancer cells

Scientists isolate antibodies capable of neutralizing dengue and Zika virus

Broccoli sprout extract may help prevent cancer recurrence in head and neck cancer survivors

Yale-led study shows how EGFR silences tumor suppressor genes

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