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Researchers reach new milestone in understanding muscle formation

Researchers from the Randall Centre for Cell & Molecular Biophysics believe they have reached a new milestone in the understanding of muscle formation that could help define new cellular and molecular approaches in pathological conditions affecting muscle wellness.

24 Oct 2018

Neurons in the brain's primary visual cortex can reliably detect straight lines

Single neurons in the brain's primary visual cortex can reliably detect straight lines, even though the cellular makeup of the neurons is constantly changing, according to a new study by Carnegie Mellon University neuroscientists, led by Associate Professor of Biological Sciences Sandra Kuhlman.

24 Oct 2018

Salk researchers advance sonogenetics technology for treating neurological conditions

The emerging technology of sonogenetics--a technique where cells are controlled by sound--offers the potential to one day replace pharmaceutical drugs or invasive surgical treatments for neurological conditions like epilepsy, Parkinson's disease or posttraumatic stress disorder.

23 Oct 2018

Researchers develop promising targeted strategy to treat chemo-resistant blood cancer

Researchers from The Ottawa Hospital and the University of Ottawa have developed a promising targeted strategy to treat chemotherapy-resistant acute myeloid leukemia and a diagnostic test to determine which AML patients would most likely benefit from this treatment.

22 Oct 2018

Paternal exercise has significant impact on child's lifelong metabolic health

Recent studies have linked development of type 2 diabetes and impaired metabolic health individuals to their parents' poor diet, and there is increasing evidence that fathers play an important role in obesity and metabolic programming of their offspring.

22 Oct 2018

Midazolam-mediated alterations of PER2 expression may have functional consequences during myocardial ischemia

Innovative cardioprotective strategies are of imminent demand. Nonfatal myocardial ischemia (MI) poses a significant risk to patients undergoing major non-cardiac surgery and these non-cardiac surgeries account for around 8 million myocardial injuries per year

19 Oct 2018

Research points to new target for treating periodontitis

T cells help fight off infection, but they can go overboard. A new study led by researchers at the University of Pennsylvania School of Dental Medicine and the National Institutes of Health shows that a subset of T cells contributes to the problematic inflammation and bone loss that is associated with periodontitis, a severe form of gum disease.

17 Oct 2018

Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation

A group of Massachusetts General Hospital investigators is proposing that targeting immune checkpoints - molecules that regulate the activity of the immune system - in immune cells called microglia could reduce the inflammatory aspects of important neurodegenerative diseases like Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis.

17 Oct 2018

Mice study shows antibiotics are not always necessary to cure sepsis

Biochemists, microbiologists, drug discovery experts and infectious disease doctors have teamed up in a new study that shows antibiotics are not always necessary to cure sepsis in mice.

17 Oct 2018

Chronic sleep disruption in early adult life accelerates AD-related tau pathology

Lack of sleep during adolescence and early adulthood accelerates Alzheimer’s disease-related tau pathology, finds a study of male and female mice published in JNeurosci.

17 Oct 2018

Researchers develop fibrin-targeting immunotherapy to protect against neurodegeneration

Normally, the blood protein fibrin does not enter the brain. But in several neurological disorders, the blood-brain barrier--which keeps large molecules in the blood from entering the brain--becomes abnormally permeable, allowing fibrin to leak into the brain and trigger inflammation.

16 Oct 2018

Study identifies molecular switch that controls fate of milk-producing breast cells

A research team, led by investigators from Georgetown Lombardi Comprehensive Cancer Center, details how a natural and dramatic process -- changes in mammary glands to accommodate breastfeeding -- uses a molecular process believed to contribute to survival of pre-malignant breast cells.

15 Oct 2018

Study: Neurons regulating reproductive hormone release have different activity in epileptic mice

Mice with epilepsy have altered patterns of neuron activity in the portion of the brain that controls the reproductive endocrine system, University of Illinois researchers report in a new study. Furthermore, the differences in neuron activity in female mice fluctuate across the reproductive cycle, the team found.

15 Oct 2018

Mouse Model News and Research

Researchers reach new milestone in understanding muscle formation

Neurons in the brain's primary visual cortex can reliably detect straight lines

Salk researchers advance sonogenetics technology for treating neurological conditions

Researchers develop promising targeted strategy to treat chemo-resistant blood cancer

Paternal exercise has significant impact on child's lifelong metabolic health

Midazolam-mediated alterations of PER2 expression may have functional consequences during myocardial ischemia

Research points to new target for treating periodontitis

Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation

Mice study shows antibiotics are not always necessary to cure sepsis

Chronic sleep disruption in early adult life accelerates AD-related tau pathology

Researchers develop fibrin-targeting immunotherapy to protect against neurodegeneration

Study identifies molecular switch that controls fate of milk-producing breast cells

Study: Neurons regulating reproductive hormone release have different activity in epileptic mice

Findings offer new insight into early changes that occur during AD pathology

Study suggests new approach to treat life-threatening blood disorder in children

New findings could benefit patients with triple-negative breast cancer

New transgenic mouse model sheds light on biological causes of Parkinson's disease

Vagus nerve stimulation can reverse brain inflammation after surgery, mice study shows

Drug treatment at a young age could help reverse autism-like behavior in tuberous sclerosis

New 3D imaging technique helps track satiety hormone

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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