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Fewer than 1 in 5 U.S. adults with Type 2 diabetes meet targets to reduce heart disease risk

Fewer than 1 in 5 adults with Type 2 diabetes in the U.S. are meeting targets to reduce heart disease risk. Fortunately, available therapies can help when combined with new approaches that address social determinants of health and other barriers to care, according to a new American Heart Association scientific statement published today in the Association's flagship journal Circulation.

10 Jan 2022

Slight pH adjustment may turn a metabolic inhibiting drug into promising COVID-19 treatment

Mechanical engineering and materials science professor David Needham has shown that a slight increase in solution pH might be all it takes to turn a metabolic inhibiting drug, traditionally used to treat gut parasites, into a promising prophylactic/preventative nasal spray and early treatment throat spray for COVID-19.

7 Jan 2022

Study identifies current mechanism of action behind reduced severity of Omicron variant COVID-19 infection

New research shows evidence that the Omicron variant is less severe compared to the Delta variant.

6 Jan 2022

New drug targeting LF and onchocerciasis begins its first in human trial in Liverpool

A new drug developed by an LSTM led partnership, which targets the neglected tropical diseases lymphatic filariasis and onchocerciasis has begun its first in human trial.

6 Jan 2022

The war on cancer at 50: The origin story begins with a socialite citizen-lobbyist

The roots of the National Cancer Act can be traced to a small home in Watertown, Wisconsin. In the early 1900s, a girl named Mary tagged along when her mother went to visit their laundress, Mrs. Belter, who had breast cancer.

6 Jan 2022

Researchers discover how oral bacteria increase vulnerability to infection

Researchers from the University of Louisville School of Dentistry and their colleagues have discovered details of how proteins produced by oral epithelial cells protect humans against viruses entering the body through the mouth.

5 Jan 2022

Wistar announces initiation of Phase 2 clinical study of VK-2019 in patients with advanced head and neck cancer

The Wistar Institute announces the initiation of a Phase 2 clinical study of VK-2019 in patients with advanced Epstein-Barr Virus (EBV)-positive nasopharyngeal carcinoma (NPC) and lymphoma.

5 Jan 2022

Oral bacteria-based SARS-CoV-2 vaccine platform

In a new study, researchers engineered the bacterial strain, Salmonella, to express differently-sized antigens to serve as vaccine platforms.

5 Jan 2022

In vitro effect of several antiviral drugs against various SARS-CoV-2 variants of concern

An independent study confirms that current and prospective antiviral treatments are effective in inhibiting severe infection from SARS-CoV-2.

4 Jan 2022

New insights into how tiny bacteria from the environment have adapted to live inside humans

The microbes that live inside our mouths, collectively known as the oral microbiome, impact our overall health in many ways that are not yet fully understood.

4 Jan 2022

Less severe clinical consequences of infection with SARS-CoV-2 Omicron variant

New evidence implies that the Omicron variant may cause a less severe and/or faster recovery from clinical COVID-19 disease.

31 Dec 2021

Recombinant adjuvanted zoster vaccination associated with lower risk of COVID-19 diagnosis and hospitalization

A new study suggests that RZV may elicit durable innate immune responses in the elderly conferring heterologous protection against COVID-19. .

30 Dec 2021

Significant gaps found in nutrition-related care for patients with kidney disease

Dietary and nutritional changes are needed when patients develop kidney disease; however, new research published in CJASN reveals that in many countries, there are significant gaps in care related to the importance of nutrition for maintaining kidney health.

29 Dec 2021

AAN issues new guideline on oral and topical treatments for painful diabetic neuropathy

Diabetic neuropathy refers to nerve damage due to diabetes and it may lead to pain and numbness, most often in the hands and feet. To help neurologists and other doctors determine the best treatment for people with diabetic neuropathy, the American Academy of Neurology (AAN) has issued a guideline on oral and topical treatments for painful diabetic neuropathy.

28 Dec 2021

Blocking function of a blood-clotting protein may help prevent or treat periodontal disease

Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, according to research led by scientists at the National Institute of Dental and Craniofacial Research, part of the National Institutes of Health.

23 Dec 2021

Study suggests nitazoxanide fails to reduce the severity of SARS-CoV-2

A new study shows that the optimization of nitazoxanide formulations may allow the review of the potential use of the drug for the treatment of SARS-CoV-2 infection.

22 Dec 2021

NIH’s new report provides a road map on how to improve Americans’ oral health

Despite important advances in the understanding and treatment of oral diseases and conditions, many people in the U.S. still have chronic oral health problems and lack of access to care, according to a report by the National Institutes of Health.

21 Dec 2021

FDA approval of long-acting injectable drug marks a vital expansion of HIV prevention options

Yesterday the U.S. Food and Drug Administration announced its first approval of a long-acting HIV prevention medication. Developed by ViiV Healthcare, the medicine is long-acting cabotegravir injected once every two months.

21 Dec 2021

Comparison of point-of-care SARS-CoV-2 diagnostic kits

A multinational group of scientists investigates the performance characteristics of several point-of-care diagnostic kits for SARS-CoV-2.

21 Dec 2021

$Clinical trial shows preliminary efficacy of all-oral regimen for patients with lenalidomide-refractory multiple myeloma$

Clinical trial shows preliminary efficacy of all-oral regimen for patients with lenalidomide-refractory multiple myeloma

Early results from an Alliance for Clinical Trials in Oncology randomized clinical trial of adults with multiple myeloma relapsing on frontline lenalidomide therapy showed that adding ixazomib (Ninlaro®) to pomalidomide and dexamethasone as part of second line therapy extended the length of time patients lived before their disease worsened (progression-free survival) compared with patients who received pomalidomide and dexamethasone.

21 Dec 2021

Oral News and Research

Fewer than 1 in 5 U.S. adults with Type 2 diabetes meet targets to reduce heart disease risk

Slight pH adjustment may turn a metabolic inhibiting drug into promising COVID-19 treatment

Study identifies current mechanism of action behind reduced severity of Omicron variant COVID-19 infection

New drug targeting LF and onchocerciasis begins its first in human trial in Liverpool

The war on cancer at 50: The origin story begins with a socialite citizen-lobbyist

Researchers discover how oral bacteria increase vulnerability to infection

Wistar announces initiation of Phase 2 clinical study of VK-2019 in patients with advanced head and neck cancer

Oral bacteria-based SARS-CoV-2 vaccine platform

In vitro effect of several antiviral drugs against various SARS-CoV-2 variants of concern

New insights into how tiny bacteria from the environment have adapted to live inside humans

Less severe clinical consequences of infection with SARS-CoV-2 Omicron variant

Recombinant adjuvanted zoster vaccination associated with lower risk of COVID-19 diagnosis and hospitalization

Significant gaps found in nutrition-related care for patients with kidney disease

AAN issues new guideline on oral and topical treatments for painful diabetic neuropathy

Blocking function of a blood-clotting protein may help prevent or treat periodontal disease

Study suggests nitazoxanide fails to reduce the severity of SARS-CoV-2

NIH’s new report provides a road map on how to improve Americans’ oral health

FDA approval of long-acting injectable drug marks a vital expansion of HIV prevention options

Comparison of point-of-care SARS-CoV-2 diagnostic kits

Clinical trial shows preliminary efficacy of all-oral regimen for patients with lenalidomide-refractory multiple myeloma

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