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Waste disposal protein key to cancer tumor suppression in autophagy

"Taking out the trash" takes on a whole new meaning, as investigators at The Cancer Institute of New Jersey (CINJ) and Rutgers, The State University of New Jersey, have discovered that a waste disposal protein is the key to cancer tumor suppression in a process known as autophagy. CINJ is a Center of Excellence of UMDNJ-Robert Wood Johnson Medical School.

13 Jun 2009

Adults have much more "brown fat" than previously thought

Keeping your baby fat turns out to be a good thing, as long as it is "brown fat" - the kind that burns calories, according to a study that found adults have much more of this type of fat than previously thought.

13 Jun 2009

$Weight loss surgery increases risk of fractures$

Weight loss surgery increases risk of fractures

After weight loss surgery, people have nearly twice the expected risk of breaking a bone and an even higher risk of a foot or hand fracture, a new study has found. The results were presented at The Endocrine Society's 91st Annual Meeting in Washington, D.C.

12 Jun 2009

How prepared are we? New study to investigate Australia’s pandemic preparedness

Public health experts have warned that a severe pandemic has the potential to cripple essential infrastructure and cause a catastrophic collapse of systems. A new study, to be undertaken by the University of New South Wales (UNSW), will assess how prepared Australia really is for a pandemic and identify 'weakest links'.

11 Jun 2009

Factors linked to failure of corneal transplants

Certain eye conditions appear to put patients at greater risk for having a failed cornea transplant, according the Cornea Donor Study (CDS), a multi-center clinical trial conducted by the National Eye Institute. The study concludes that patients with glaucoma and patients who had corneal swelling following an earlier cataract surgery were more likely to experience failure of the cornea transplant than were other patients in the study.

11 Jun 2009

Potential new way to treat childhood epilepsy

Rutgers researchers have discovered a potential new way to treat childhood epilepsy using a widely available therapeutic drug.

10 Jun 2009

Discovery of biomarker that predicts the outcome of certain breast cancers

Scientists have found a new biomarker that can predict the outcome of breast cancers that have spread to the lymph nodes, reveal findings published in the British Journal of Cancer today (Wednesday).

10 Jun 2009

Elective surgery in Canberra a waiting game

According to the latest report from the Australian Institute of Health and Welfare (AIHW) people living in Canberra wait on average 72 days for elective surgery which is more than double the national average of 34 days.

9 Jun 2009

Impliant granted two new U.S. patents - successfully defends European patent

Impliant, Inc., a developer of novel spine arthroplasty alternatives to fusion surgery, today announced that the European Patent Office has confirmed the validity of one of its key patents following an Opposition by Archus Orthopedics, Inc. (Redmond, WA) that concluded with oral proceedings on May 12, 2009 in Munich, Germany.

9 Jun 2009

Discovery of new angiogenesis protein - possible cancer drug target

To grow and spread, tumors need new blood vessels, a process called angiogenesis. One growth factor that causes angiogenesis has been identified - vascular endothelial growth factor or VEGF - and drugs to inhibit VEGF are already in use. But not all tumors respond to the therapy initially or over the long term. Thus new growth factors need to be identified to aid in developing the next generation of angiogenesis inhibitors.

9 Jun 2009

Seniors who use cardiac rehabilitation live longer, study finds

Coronary heart disease (CHD) is the leading cause of death worldwide and a major driver of medical and economic costs, especially among older adults. It has long been established that cardiac rehabilitation improves survival, at least in middle-aged, low- and moderate-risk white men. Now a large Brandeis University-led study published in the Journal of the American College of Cardiology reports that older cardiac patients benefit as much from cardiac rehab as their younger counterparts.

9 Jun 2009

New lung cancer therapy with vaporized viral vector shows promise

A new lung cancer therapy employing a vaporized viral vector to deliver a cancer-inhibiting molecule directly to lung tissue shows early promise in mouse trials, according to researchers at the Ministry of Education, Science and Technology in Korea.

9 Jun 2009

New report on obesity calls for better designed urban areas

A new report from the House of Representatives Standing Committee on Health and Ageing on obesity in Australia has called for some major changes in the way Australians live today.

8 Jun 2009

Diabetes with coronary disease: A moving target amid evolving therapies

In an editorial in the current issue of the New England Journal of Medicine (NEJM), William E. Boden, M.D., professor of medicine and preventive medicine at the University at Buffalo, recommends that the results of the BARI-2D Trial published in that edition must be interpreted with "considerable caution."

8 Jun 2009

Researchers find clues to improve breast cancer survival

Checking lymph nodes during surgery and assessing the hormone status of tumours could help improve breast cancer survival in the UK, according to research published in Annals of Oncology.

8 Jun 2009

Australian researchers advance bowel cancer detection

Australian researchers have developed gene expression biomarkers which can accurately discriminate pre-cancerous and cancerous colorectal growths from non-cancerous controls.

4 Jun 2009

Discovery of critical marker of response to gemcitabine in pancreatic cancer

A protein related to aggressive cancers can actually improve the efficacy of gemcitabine at treating pancreatic cancer, according to a Priority Report in Cancer Research, published by researchers at Thomas Jefferson University.

4 Jun 2009

Research investigates the treatment of traumatic brain and head injury

The National Institute for Health Research Health Technology Assessment (NIHR HTA) programme is expanding the evidence base surrounding the treatment of traumatic brain and head injury (TBI) by commissioning four new research projects. If left untreated many patients with head injury will rapidly develop complications which may lead to death or permanent disability. More than 100,000 people in the UK have long-term effects caused by such injuries. Prompt medical treatment may prevent the worsening of symptoms and lead to a better outcome.

4 Jun 2009

Research looks at bariatric surgery waiting times in Canada

Obesity is now acknowledged as a chronic disease with a number of related complications, and its prevalence has reached alarming epidemic proportions. While bariatric surgery is effective at treating the disease, access to this procedure is still too limited in Canada.

3 Jun 2009