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AP39 compound could help lower heart rate, blood pressure, and blood vessel stiffness

A gas that gives rotten eggs their distinctive odour could one day form the basis of new cardiovascular therapies.

29 Jan 2015

Sebacia reports positive clinical results from two independent studies in people with acne

Sebacia, Inc., a company dedicated to delivering breakthrough topical treatments to advance dermatology, has announced the presentation of positive clinical results from two independent studies conducted in Europeinvestigating the use of Sebacia gold microparticles to treat acne.

29 Jan 2015

Loyola psychiatrist offers tips to cope with football withdrawal symptoms

When the football seasons with the final play of Sunday's Super Bowl, some fans may begin to feel withdrawal symptoms.

29 Jan 2015

Scientists publish catalog of genetic mutations found in head and neck cancers

Scientists have published the first comprehensive catalog of genetic mutations and other abnormal changes found in 279 cancers of the head and neck, and have identified several broken molecular pathways that might be targeted by existing and future cancer drugs.

28 Jan 2015

Study: Green tea compound may activate a cycle that kills oral cancer cells

A compound found in green tea may trigger a cycle that kills oral cancer cells while leaving healthy cells alone, according to Penn State food scientists. The research could lead to treatments for oral cancer, as well as other types of cancer.

28 Jan 2015

Researchers one step closer to identifying how lung cancer cells metastasize

Smoking is the leading cause of lung cancer, and it is estimated that more than 159,000 people in the United States died from the disease last year. Most of these deaths were because the cancer had spread to other organ sites. Following their recent discovery of a protein pathway, Moffitt Cancer Center researchers are one step closer to understanding how lung cancer cells metastasize.

28 Jan 2015

ADDF awards grant to support initiation of AGB101 Phase 3 trial for aMCI treatment

The Alzheimer's Drug Discovery Foundation announced today a $900,000 grant to AgeneBio, a pharmaceutical company developing innovative therapies for neurologic and psychiatric diseases. The grant will support the initiation of an FDA-registered Phase 3 clinical trial of AGB101, a new therapeutic treatment for amnestic mild cognitive impairment (aMCI).

28 Jan 2015

Manchester researcher discover novel way to eradicate cancer stem cells

A way to eradicate cancer stem cells, using the side-effects of commonly used antibiotics, has been discovered by a University of Manchester researcher following a conversation with his young daughter.

28 Jan 2015

TGH develops unique new method to help high-risk patients receive a lung transplant

A unique new method to treat a specific group of patients who are at greater risk of rejecting a donor lung, allowing them to live longer after transplant without rejection, has been developed by the Toronto Lung Transplant Program at Toronto General Hospital, University Health Network.

28 Jan 2015

Reducing A2A adenosine receptor levels prevents memory impairments in Alzheimer's mouse model

A study by scientists from the Gladstone Institutes shows that decreasing the number of A2A adenosine receptors in a particular type of brain cells called astrocytes improved memory in healthy mice. What's more, reducing receptor levels also prevented memory impairments in a mouse model of Alzheimer's disease.

28 Jan 2015

Researchers probe possibility of reversing medications' adverse cognitive effects

Whether the adverse cognitive effects of medications can be reversed is of significant importance to an aging population, their caregivers and their families, as well as to an overburdened health care system.

28 Jan 2015

Hutchinson-Gilford Progeria Syndrome can be compared to normal aging, say scientists

In a new research study, scientists from Vision Genomics, LLC, Insilico Medicine, Inc., and Howard University showed that Hutchinson-Gilford Progeria Syndrome (HGPS or Progeria) is comparable to normal aging with respect to cellular signaling pathways, and that HGPS truly recapitulates the normal aging process.

28 Jan 2015

Silencing neurons in the arcopallium

New research published by the Neuronal Mechanism for Critical Period Unit at the Okinawa Institute of Science and Technology Graduate University has shown the effectiveness of chemogenetic inhibition used to suppress neuronal activity as well as interesting results on how vocalization is controlled through this techniques application in zebra finches.

28 Jan 2015

Antibiotic use by travellers may promote spread of drug-resistant 'super-bacteria'

Treating travellers' diarrhoea with antibiotics can promote the spread of drug-resistant "super-bacteria".

28 Jan 2015

Ghrelin hormone supplement increases sexual activity in mice

Swedish studies show that mice that receive a supplement of the "appetite hormone" ghrelin increase their sexual activity. Whether the hormone has the same impact on humans is unknown - but if it does, the researchers may have found the key to future treatments for sex abuse.

28 Jan 2015

Investigators make medical breakthrough in repairing tracheal damage

Investigators at The Feinstein Institute for Medical Research have made a medical breakthrough using 3D printing on a MakerBot Replicator 2X Experimental 3D Printer to create cartilage designed for tracheal repair or replacement.

28 Jan 2015

Plymouth researchers awarded grant to evaluate pulmonary rehabilitation programme in East Africa

Chronic lung disease is a growing and debilitating health issue for countries in East Africa. Resulting from respiratory infections such as TB and HIV, and lifestyle problems such as tobacco smoking and poor nutrition, chronic lung disease affects one in five adults in Africa and is a major threat to health.

28 Jan 2015

Androgen receptor in prostate cancer cells can activate different gene set when bound to antiandrogens

The androgen receptor in prostate cancer cells can activate different sets of genes depending on whether it binds with an androgen hormone or an antiandrogen drug, according to a new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

28 Jan 2015

New survey finds long-term benefits of brain surgery in patients with epilepsy

Brain surgery for otherwise hard-to-treat epilepsy is effective for up to 15 years, according to a new survey by Henry Ford Hospital physicians.

28 Jan 2015

Purdue University researchers find promising way to treat late-stage prostate cancer

Low doses of metformin, a widely used diabetes medication, and a gene inhibitor known as BI2536 can successfully halt the growth of late-stage prostate cancer tumors, a Purdue University study finds.

28 Jan 2015

Drugs News and Research

AP39 compound could help lower heart rate, blood pressure, and blood vessel stiffness

Sebacia reports positive clinical results from two independent studies in people with acne

Loyola psychiatrist offers tips to cope with football withdrawal symptoms

Scientists publish catalog of genetic mutations found in head and neck cancers

Study: Green tea compound may activate a cycle that kills oral cancer cells

Researchers one step closer to identifying how lung cancer cells metastasize

ADDF awards grant to support initiation of AGB101 Phase 3 trial for aMCI treatment

Manchester researcher discover novel way to eradicate cancer stem cells

TGH develops unique new method to help high-risk patients receive a lung transplant

Reducing A2A adenosine receptor levels prevents memory impairments in Alzheimer's mouse model

Researchers probe possibility of reversing medications' adverse cognitive effects

Hutchinson-Gilford Progeria Syndrome can be compared to normal aging, say scientists

Silencing neurons in the arcopallium

Antibiotic use by travellers may promote spread of drug-resistant 'super-bacteria'

Ghrelin hormone supplement increases sexual activity in mice

Investigators make medical breakthrough in repairing tracheal damage

Plymouth researchers awarded grant to evaluate pulmonary rehabilitation programme in East Africa

Androgen receptor in prostate cancer cells can activate different gene set when bound to antiandrogens

New survey finds long-term benefits of brain surgery in patients with epilepsy

Purdue University researchers find promising way to treat late-stage prostate cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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