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Latent CMV infection induces telomere shortening

The telomeres are repetitive DNA sequences at each end of our chromosomes. Studies show that in every cell division, the telomere is shortened. As a result, the telomere limits the cell to a fixed number of divisions and a limited life span. An essential part of human cells they affect how our cells age - as people with longer telomeres live longer lives. Surprisingly, people who are infected with a latent virus, that is, an asymptomatic virus, have shorter telomeres.

2 Jul 2015

New research links mutations in TEX11 gene to some cases of male infertility

In the most severe form of male infertility, men do not make any measurable levels of sperm. This condition, called azoospermia, affects approximately 1 percent of the male population and is responsible for about a sixth of cases of male infertility.

2 Jul 2015

Domainex’s new integrated bioassay service platform accelerates progression of drug discovery projects

Domainex Ltd, a private drug discovery service company, today announces that it is launching an integrated bioassay service platform, BioassayBuilder.

2 Jul 2015

Histones steadily replaced in brain cells throughout life, find Mount Sinai researchers

For decades, researchers in the genetics field have theorized that the protein spools around which DNA is wound, histones, remain constant in the brain, never changing after development in the womb.

2 Jul 2015

HIV capsid protein plays crucial role in the virus' life cycle

HIV, or human immunodeficiency virus, is the retrovirus that leads to acquired immunodeficiency syndrome or AIDS. Globally, about 35 million people are living with HIV, which constantly adapts and mutates creating challenges for researchers. Now, scientists at the University of Missouri are gaining a clearer idea of what a key protein in HIV looks like, which will help explain its vital role in the virus' life cycle.

2 Jul 2015

IBI scientists make progress in identifying new biomarkers for preventing colorectal cancer

Scientists from the Instituto de Investigación Biomédica [Institute of Biomedical Research], in Galicia (Spain), have made progress in the identification of new biomarkers for improving prevention of colorectal cancer.

1 Jul 2015

Scientists identify new protein that affects growth of secondary breast tumours in the brain

Scientists from the University of Leeds and The Institute of Cancer Research, London, have discovered a new protein which triggers the growth of blood vessels in breast cancer tumours which have spread to the brain, a common location which breast cancer can spread to.

1 Jul 2015

Damon Runyon creates new award to increase number of physician-scientists

Physician-scientists are crucial to moving scientific discoveries from the lab to patients, but their numbers have been dwindling just when they are needed most, particularly in cancer research, as the number of cancer cases is projected to increase by 45 percent in the next fifteen years and elevate cancer to the leading cause of death in America.

1 Jul 2015

Researchers use pioneering stem cell techniques to better understand causes of Spinal Muscular Atrophy

New research from the Advanced Gene and Cell Therapy Lab at Royal Holloway, University of London has used pioneering stem cell techniques to better understand why certain cells are more at risk of degenerating in Spinal Muscular Atrophy than others.

1 Jul 2015

Nuclea and Aelan partner to develop, commercialize novel biomarker tests using STEM cells as models

Nuclea Biotechnologies Inc. announced today that it is partnering with Aelan Cell Technologies Inc. (San Francisco, California) for the development, validation and commercialization of novel biomarker tests and companion diagnostics using human STEM cells as models.

1 Jul 2015

Bibby Scientific’s Integrity 10 Reaction Station helps scientists to speed up drug development research

Analytical scientists at the University of Lincoln’s School of Pharmacy are accelerating their drug development research thanks to Bibby Scientific’s Integrity 10 Reaction Station, which enables different reactions to be performed simultaneously with varied process conditions.

1 Jul 2015

UCSD researchers discover cell signaling pathway that controls initiation, progression of colorectal cancer

Researchers at University of California, San Diego School of Medicine have discovered a cell signaling pathway that appears to exert some control over initiation and progression of colorectal cancer, the third leading cause of cancer-related death in the United States. A key protein in the pathway also appears to be predictive of cancer survival rates.

1 Jul 2015

Omega-3 fatty acids and antioxidants may benefit people with Alzheimer's disease

Here's more evidence that fish oil supplementation and antioxidants might be beneficial for at least some people facing Alzheimer's disease: A new report published in the July 2015 issue of The FASEB Journal describes the findings of a very small study in which people with mild clinical impairment, such as those in the very early stages of the disease, saw clearance of the hallmark amyloid-beta protein and reduced inflammation in neurological tissues.

1 Jul 2015

Tree nut consumption associated with lower body weight and lower risk of obesity

In a study published this week in Nutrition Journal*, researchers compared risk factors for heart disease and metabolic syndrome of tree nut consumers versus those who did not consume tree nuts. Tree nut (almonds, Brazil nuts, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and walnuts) consumption was associated with lower body mass index (p=0.004), systolic blood pressure (p=0.001), insulin resistance (p=0.043) and higher levels of high-density lipoprotein-cholesterol (good cholesterol) (p=0.022).

30 Jun 2015

Researchers map physical properties of live breast cancer cells using advanced AFM technology

Researchers who developed a high-speed form of atomic force microscopy have shown how to image the physical properties of live breast cancer cells, for the first time revealing details about how deactivation of a key protein may lead to metastasis.

30 Jun 2015

Researchers explore why some mutations can cause severe disease in humans, but benign in animals

Researchers at Duke University School of Medicine and Brigham and Women's Hospital, Harvard Medical School have identified a mechanism that explains why some mutations can be disease-causing in one genome but benign in another.

30 Jun 2015

Imperial College London researchers discover new inherited form of obesity, type 2 diabetes

Scientists have discovered a new inherited form of obesity and type 2 diabetes in humans. A large number of genes are involved in regulating body weight, and there are now over 30 genes known in which people with harmful changes in DNA sequence become extremely overweight. Similarly, there are a number of genes that can, when altered, cause type 2 diabetes. These conditions are inherited through families in exactly the same way as disorders such as cystic fibrosis or Huntington's disease.

30 Jun 2015

Researchers complete participants’ enrollment in Phase III trial of vaginal ring for HIV prevention

In a first for HIV prevention, an international team of researchers have completed follow-up of participants enrolled in a pivotal Phase III trial that tested the safety and effectiveness of a vaginal ring for preventing HIV in women.

30 Jun 2015

New informatics technology could accelerate search for potential new drug targets on protein structures

Researchers have developed a new informatics technology that analyzes existing data repositories of protein modifications and 3D protein structures to help scientists identify and target research on "hotspots" most likely to be important for biological function.

30 Jun 2015

New discovery could lead to personalized treatment for colon cancer

A UNC Lineberger Comprehensive Cancer Center discovery of just how a certain tumor suppressor molecule works to prevent tumor growth could lead to a personalized treatment approach for colon cancer.

30 Jun 2015

Protein C News and Research

Latent CMV infection induces telomere shortening

New research links mutations in TEX11 gene to some cases of male infertility

Domainex’s new integrated bioassay service platform accelerates progression of drug discovery projects

Histones steadily replaced in brain cells throughout life, find Mount Sinai researchers

HIV capsid protein plays crucial role in the virus' life cycle

IBI scientists make progress in identifying new biomarkers for preventing colorectal cancer

Scientists identify new protein that affects growth of secondary breast tumours in the brain

Damon Runyon creates new award to increase number of physician-scientists

Researchers use pioneering stem cell techniques to better understand causes of Spinal Muscular Atrophy

Nuclea and Aelan partner to develop, commercialize novel biomarker tests using STEM cells as models

Bibby Scientific’s Integrity 10 Reaction Station helps scientists to speed up drug development research

UCSD researchers discover cell signaling pathway that controls initiation, progression of colorectal cancer

Omega-3 fatty acids and antioxidants may benefit people with Alzheimer's disease

Tree nut consumption associated with lower body weight and lower risk of obesity

Researchers map physical properties of live breast cancer cells using advanced AFM technology

Researchers explore why some mutations can cause severe disease in humans, but benign in animals

Imperial College London researchers discover new inherited form of obesity, type 2 diabetes

Researchers complete participants’ enrollment in Phase III trial of vaginal ring for HIV prevention

New informatics technology could accelerate search for potential new drug targets on protein structures

New discovery could lead to personalized treatment for colon cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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