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Researchers reveal how melanoma becomes resistant to promising new drug combo therapy

In a new study led by UCLA Jonsson Comprehensive Cancer Center member Dr. Roger Lo, researchers have uncovered how melanoma becomes resistant to a promising new drug combo therapy utilizing BRAF+MEK inhibitors in patients after an initial period of tumor shrinkage.

16 Jan 2015

CUMC researchers identify that OCR stem cells can regenerate bone and cartilage in mice

A stem cell capable of regenerating both bone and cartilage has been identified in bone marrow of mice. The discovery by researchers at Columbia University Medical Center is reported today in the online issue of the journal Cell.

16 Jan 2015

Study: Century-old drug may help treat autism

Autism spectrum disorders (ASD) affect 1 to 2 percent of children in the United States. Hundreds of genetic and environmental factors have been shown to increase the risk of ASD. Researchers at UC San Diego School of Medicine previously reported that a drug used for almost a century to treat trypanosomiasis, or sleeping sickness, reversed environmental autism-like symptoms in mice.

16 Jan 2015

New research helps explain why pancreatic cancer is so lethal

New research from the University of Michigan Comprehensive Cancer Center helps explain why pancreatic cancer is so lethal, with fewer than a third of patients surviving even early stage disease.

16 Jan 2015

AbbVie gets European Commission's approval to market VIEKIRAX + EXVIERA for HCV treatment

AbbVie announced that the European Commission has granted marketing authorizations for its all-oral, short-course, interferon-free treatment of VIEKIRAX (ombitasvir/paritaprevir/ritonavir tablets) + EXVIERA (dasabuvir tablets). The treatment has been approved with or without ribavirin (RBV) for patients with genotype 1 (GT1) chronic hepatitis C virus (HCV) infection, including those with compensated liver cirrhosis, HIV-1 co-infection, patients on opioid substitution therapy and liver transplant recipients.

16 Jan 2015

Endocrine Society issues guideline on prescribing drugs to manage obesity, promote weight loss

The Endocrine Society today issued a Clinical Practice Guideline (CPG) on strategies for prescribing drugs to manage obesity and promote weight loss.

16 Jan 2015

First medical device approved for treatment of obesity

The United States Food and Drug Administration approved EnteroMedic's VBLOC vagal blocking therapy, delivered via the Maestro System, which is the first medical device approved for obesity treatment that targets the nerve pathway between the brain and the stomach.

15 Jan 2015

MRIGlobal awarded $54 million NIH contract to provide support for drug development

MRIGlobal today announced that it has been awarded a $54 million, 10-year program from the National Institute of Neurological Disorders and Stroke to provide support for the development and manufacturing of drug candidates for ultimate use in human clinical trials.

15 Jan 2015

Researchers assess the effect of IPT for children with anaemia in malaria endemic regions

Researchers from Tanzania and South Africa, who are part of the Cochrane Infectious Disease Group, hosted at LSTM, have conducted an independent review to assess the effect of intermittent preventive antimalarial treatment (IPT) for children with anaemia living in malaria endemic regions. This is a strategy of giving a treatment dose of antimalarial drugs to children at regular intervals just in case they have become infected.

15 Jan 2015

Endocrinology Network offers up-to-date coverage of SGLT2 inhibitors

UBM Medica US announces that Endocrinology Network, a leading online community for endocrinologists and other clinicians who treat patients with T2DM offers comprehensive and up-to-date coverage of the sodium glucose cotransporter 2 (SGLT2) inhibitors.

15 Jan 2015

Scientists identify first genetic marker linked to severe neurological toxicity

Paclitaxel is a chemotherapeutic drug that has been shown to be highly effective when treating solid tumours, such as breast, ovarian and lung tumours. However, its use frequently causes peripheral neuropathies, neurological problems that affect the vast majority of patients.

15 Jan 2015

GSU researchers discover how steroids use a novel 'trick' to suppress inflammation

A new "trick" steroids use to suppress inflammation, which could be used to make new anti-inflammatory drugs without the harmful side effects of steroids, has been discovered by researchers at Georgia State University.

15 Jan 2015

European countries implement ATOME project to study improved access to essential painkillers

Governments in 12 European countries are to implement the recommendations of research into why more patients are not receiving essential painkillers.

15 Jan 2015

NIAID awards contracts to support early-stage human clinical trials of infectious disease treatments

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has awarded contracts to three organizations to support early-stage human clinical trials of investigational infectious disease treatments. The new awards for the Phase I Clinical Trial Units for Therapeutics increases the number of funded organizations under the program from two to three, expanding capacity for conducting early safety testing of novel investigational drugs.

15 Jan 2015

Neurobiologists find paradoxical effect of abuse-related cues in infants, adults

Neurobiologists at NYU Langone Medical Center and elsewhere have found a surprising and paradoxical effect of abuse-related cues in rat pups: those cues also can lower depressive-like behavior when the rat pups are fully grown.

14 Jan 2015

Study finds increase in overall survival in patients with metastatic colorectal cancer

With the dawn of the modern era of new chemotherapeutic and biologic agents available for managing their disease, patients with metastatic colorectal cancer are undergoing less surgery for the removal of their primary tumors, according to research from The University of Texas MD Anderson Cancer Center.

14 Jan 2015

3SBio, PharmAbcine sign licensing agreement to develop and market DIG-KT

3SBio Inc., a leading China-based biotechnology company focused on researching, developing, manufacturing and marketing biopharmaceutical products, today announced it has entered into an exclusive licensing deal with PharmAbcine Inc. for the development, manufacturing and marketing of DIG-KT, a bi-specific monoclonal antibody ("mAb") targeting both VEGFR2/KDR and Tie-2 pathways for cancer in the territory of Greater China (including mainland China, Taiwan, Hong Kong and Macau) and Korea.

14 Jan 2015

Individualized, patient-centered care needed to treat and monitor people with chronic pain

An independent panel convened by the National Institutes of Health concluded that individualized, patient-centered care is needed to treat and monitor the estimated 100 million Americans living with chronic pain. To achieve this aim, the panel recommends more research and development around the evidence-based, multidisciplinary approaches needed to balance patient perspectives, desired outcomes, and safety.

14 Jan 2015

Researchers identify new target that could lead to potential therapies for GBM

Researchers from Virginia Commonwealth University Massey Cancer Center and the VCU Institute for Molecular Medicine have identified a new protein-protein interaction that could serve as a target for future therapies for the most common form of brain cancer, glioblastoma multiforme (GBM).

14 Jan 2015

Life satisfaction associated with higher bone density in older women

Women aged 60-70 who are satisfied with their lives have a higher bone density and they suffer from osteoporosis less frequently than their unsatisfied peers, according to a recent study completed at the University of Eastern Finland.

14 Jan 2015

Drugs News and Research

Researchers reveal how melanoma becomes resistant to promising new drug combo therapy

CUMC researchers identify that OCR stem cells can regenerate bone and cartilage in mice

Study: Century-old drug may help treat autism

New research helps explain why pancreatic cancer is so lethal

AbbVie gets European Commission's approval to market VIEKIRAX + EXVIERA for HCV treatment

Endocrine Society issues guideline on prescribing drugs to manage obesity, promote weight loss

First medical device approved for treatment of obesity

MRIGlobal awarded $54 million NIH contract to provide support for drug development

Researchers assess the effect of IPT for children with anaemia in malaria endemic regions

Endocrinology Network offers up-to-date coverage of SGLT2 inhibitors

Scientists identify first genetic marker linked to severe neurological toxicity

GSU researchers discover how steroids use a novel 'trick' to suppress inflammation

European countries implement ATOME project to study improved access to essential painkillers

NIAID awards contracts to support early-stage human clinical trials of infectious disease treatments

Neurobiologists find paradoxical effect of abuse-related cues in infants, adults

Study finds increase in overall survival in patients with metastatic colorectal cancer

3SBio, PharmAbcine sign licensing agreement to develop and market DIG-KT

Individualized, patient-centered care needed to treat and monitor people with chronic pain

Researchers identify new target that could lead to potential therapies for GBM

Life satisfaction associated with higher bone density in older women

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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