Apoptosis News and Research

RSS

Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.

New information about how normal cells and cancer cells survive under stress

Scientists report that an evolutionarily conserved transcription factor may have both positive and negative effects on the growth of tumors, depending on whether or not the tumor cells have enough oxygen.

28 Dec 2007

Cardiac stem cell therapy research

Since the year 2000, much has been learned about the potential for using transplanted cells in therapeutic efforts to treat varieties of cardiac disorders.

28 Dec 2007

Plant constituent with selective effect on cancer cells

The substance wogonin triggers the death program apoptosis in tumor cells, while it has virtually no effect on healthy cells.

18 Dec 2007

Agent orange chemical, dioxin, attacks the mitochondria to cause cancer

Researchers with the University of Pennsylvania School of Veterinary Medicine have demonstrated the process by which the cancer-causing chemical dioxin attacks the cellular machinery, disrupts normal cellular function and ultimately promotes tumor progression.

18 Dec 2007

Complex path to cell death shown by identification of new genes

Can a tiny winged insect's salivary glands really tell us about processes relevant to human disease? Yes, according to a new study by researchers at the University of Massachusetts Medical School (UMMS), who gained new insights into autophagy - a cellular degradation process associated with a form of programmed cell death - by studying the salivary gland cells of the fruit fly.

17 Dec 2007

Treatment with secretoneurin reduces injury to the brain following stroke

Stroke is the term used to describe deteriorating brain function due to either the leaking of blood vessels (hemorrhage) or oxygen deprivation (ischemia) in the brain.

14 Dec 2007

Genes discovered that protect against heart damage from chemotherapy

A series of genes that protect cells from the powerful, common chemotherapeutic agent doxorubicin has been identified by researchers working to understand how the drug also can destroy the heart.

4 Dec 2007

Discovery of key acute myeloid leukemia gene

A gene called N-Myc leads a double life in certain white blood cells, helping to trigger a cancer called acute myeloid leukemia (AML) under some conditions while triggering apoptosis, or cell suicide, under other conditions, according to results of a mouse study done by investigators at St. Jude Children's Research Hospital.

27 Nov 2007

Pregnant women pass on the effects of smoking

Smoking during pregnancy has many adverse effects on fetal development.

21 Nov 2007

Bortezomib pushes cancer cells into overdrive, so that they self-destruct

University of Michigan Comprehensive Cancer Center researchers have discovered that bortezomib, a promising cancer drug, is able to strike a blow against melanoma tumor cells by revving up the action of a cancer-promoting gene.

21 Nov 2007

How inhibitor-of-apoptosis chemicals kill tumors

Chemical compounds specially designed to neutralize proteins that would otherwise allow tumor cells to cheat death have been recognized for some time by scientists as a promising new avenue for cancer therapy.

16 Nov 2007

Synthetic compound promotes death of lung-cancer cells, tumors

Human lung-cancer tumors grown in mice have been shown to regress or disappear when treated with a synthetic compound that mimics the action of a naturally occurring "death-promoting" protein found in cells, researchers at UT Southwestern Medical Center report.

13 Nov 2007