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Novel ligand peptide-mimic inhibits abnormal overgrowth of blood vessels, may lead to new anti-cancer drugs

An international research team led by scientists at the University of New Mexico Cancer Center discovered and developed a novel ligand peptide-mimic that inhibits abnormal overgrowth of blood vessels in retinal diseases and tumors. The discovery could lead to new drugs that keep cancers from growing. The team published a paper in the journal Science Translational Medicine.

15 Oct 2015

Scientists identify culprit genes behind the formation and progression of breast tumours

A team from the SingHealth Duke-NUS Academic Medical Centre, comprising scientists and clinicians from the National Cancer Centre Singapore, Singapore General Hospital and Duke-NUS Graduate Medical School, has uncovered the genetic landscape of a distinct breast tumour group called fibroepithelial tumours.

8 Oct 2015

Two researchers awarded NIH's New Innovator and Early Independence Awards

Two researchers, Martin Jonikas of Carnegie's Department of Plant Biology and Zhao Zhang of the Department of Embryology, have been awarded the New Innovator and Early Independence Awards, respectively, from the National Institutes of Health.

7 Oct 2015

Experimental drug shows promise in mice with multiple sclerosis

An experimental drug originally identified in a National Cancer Institute library of chemical compounds as a potential therapy for brain and basal cell cancers improves the symptoms of mice with a form of the debilitating neurological disorder multiple sclerosis (MS), according to new research from NYU Langone Medical Center.

1 Oct 2015

Research shows why microgravity leads to muscle loss

People can easily feel the presence - or absence - of gravity. Our individual cells actually may be able to sense gravity, too, and that ability could play a role in the loss of muscle that occurs when humans spend time in space.

1 Oct 2015

New study on deep-diving whales may help researchers create synthetic blood for human trauma patients

The ultra-stable properties of the proteins that allow deep-diving whales to remain active while holding their breath for up to two hours could help Rice University biochemist John Olson and his colleagues finish a 20-year quest to create lifesaving synthetic blood for human trauma patients.

26 Sep 2015

UCSF researchers map genetic signature of unusual stem cells in the human brain

The human cerebral cortex contains 16 billion neurons, wired together into arcane, layered circuits responsible for everything from our ability to walk and talk to our sense of nostalgia and drive to dream of the future. In the course of human evolution, the cortex has expanded as much as 1,000-fold, but how this occurred is still a mystery to scientists.

25 Sep 2015

Research highlights potential new treatment strategy for degenerative diseases

St. Jude Children's Research Hospital scientists have discovered evidence of a mechanism at the heart of amyotrophic lateral sclerosis (ALS) and related degenerative diseases. The research appears in today's edition of the journal Cell and highlights a possible new treatment strategy for the devastating disorders.

25 Sep 2015

UNC Lineberger earns 'exceptional' rating from NCI for major grant application

The UNC Lineberger Comprehensive Cancer Center earned an "exceptional" rating from the National Cancer Institute for a major grant application associated with the center's multidisciplinary research.

23 Sep 2015

New genetic cause identified for congenital heart arrhythmia

Scientists at The Ohio State University Dorothy M. Davis Heart and Lung Research Institute have identified a new genetic cause for congenital heart arrhythmia. The results of their research are published online by the Proceedings of the National Academy of Sciences (PNAS).

23 Sep 2015

Drug combination delivers effective punch against one form of pancreatic cancer

One form of pancreatic cancer has a new enemy: a two-drug combination discovered by UF Health researchers that inhibits tumors and kills cancer cells in mouse models.

22 Sep 2015

Innovative way may stop spread of glioblastoma multiforme

Scientists at the University of Toledo Health Science Campus and Van Andel Research Institute have discovered an innovative way that may stop the spread of the most lethal and aggressive brain cancer glioblastoma multiforme (GBM). In laboratory studies, scientists demonstrated that activating a specific family of proteins halted cancer cell migration into healthy tissue.

22 Sep 2015

Scientists uncover how embryonic stem cells inhibit virus expression

Scientists from the Institute of Molecular and Cell Biology, a research institute under the Agency for Science, Technology and Research, Singapore, have uncovered the mechanisms which embryonic stem cells employ to inhibit virus expression.

22 Sep 2015

Thomas Jefferson University provides routine genomic fingerprinting to cancer patients

Cancer medicine is moving towards understanding what drives each particular patient's cancer. But not every patient has had access to this level of individualized care.

18 Sep 2015

Researchers discover new import pathway used by proteins to reach mitochondria

Mitochondria serve as the powerhouses of the cell, converting the energy stored in foods into a form cells can use. When this important task fails, it can result in numerous diseases, particularly those affecting organs with a high energy consumption like the brain or the heart.

18 Sep 2015

Study shows link between impaired mitochondria, energy failure, and neuronal dysfunction

A new study from the Gladstone Institutes shows for the first time that impairments in mitochondria--the brain's cellular power plants--can deplete cellular energy levels and cause neuronal dysfunction in a model of neurodegenerative disease.

15 Sep 2015

Researchers discover new strategy for attacking cancer cells

University of Virginia School of Medicine researchers have discovered a new strategy for attacking cancer cells that could fundamentally alter the way doctors treat and prevent the deadly disease.

11 Sep 2015

UVA researchers identify new strategy for attacking cancer cells

University of Virginia School of Medicine researchers have discovered a new strategy for attacking cancer cells that could fundamentally alter the way doctors treat and prevent the deadly disease. By more selectively targeting cancer cells, this method offers a strategy to reduce the length of and physical toll associated with current treatments.

10 Sep 2015

Masayo Takahashi awarded inaugural Ogawa-Yamanaka Stem Cell Prize

The Gladstone Institutes is pleased to present the inaugural Ogawa-Yamanaka Stem Cell Prize to Masayo Takahashi, MD, PhD, a faculty member and project leader in the Laboratory for Retinal Regeneration at the RIKEN Centre for Developmental Biology in Japan.

10 Sep 2015

MD Anderson's Jim Allison named winner of 2015 Lasker-DeBakey Clinical Medical Research Award

For inventing a completely new way to strike cancer by unlocking a shackled immune system attack, Jim Allison, Ph.D., chair of Immunology at The University of Texas MD Anderson Cancer Center, will receive the nation's highest honor for clinical medical research.

9 Sep 2015