At the 2015 Cell Biology ASCB Annual Meeting, Bruker today announced the release of the first quantitative super-resolution microscope, the Vutara™ 352.
The Vutara 352 offers speed, imaging depth, and resolution to deliver significant advantages over competing approaches, now also adding real-time quantitative capabilities.
For the first time, this represents an entirely new dimension of functionality in super-resolution microscopy, including the ability to perform pair-correlation, co-location, cluster, and live-cell analysis with super resolution.
The Vutara 352 is now also compatible with Bruker’s Opterra multi-point confocal microscope, creating a unique combination of super-resolution and confocal capabilities, where both instruments are designed for high-speed imaging.
This enables the visualization of large-scale, high-resolution structural context in correlation with super-resolution imaging in even the most challenging live-cell applications.
Single molecule localization techniques are unique in that the images are constructed from discrete, molecular-scale events.”
“Unlike any other super-resolution system, the Vutara 352’s new proprietary algorithms leverage this benefit, enabling researchers to conduct immediate quantitative analysis on their biology. "
"Only the Vutara 352 utilizes the highest 3D resolution to quantify molecular co-location, or the fastest imaging speeds to identify, track, and quantify fluorescent clusters in live-cells.”
Stephen C. Minne, Ph.D., General Manager of Bruker's Fluorescence Microscopy Business.
“The Opterra-SR confocal scanner has provided us with a significant enhancement to our Vutara system,” said Dr. Robert Hobson from the Department of Biology at the University of Utah.
“We can now perform imaging across a range of modalities, including confocal imaging and super-resolution imaging. The fast deconvolution of confocal images provides us with a much clearer picture of samples of interest at high resolution to complement our super-resolution imaging. The addition of the quantitative analysis tools allows us to ask more detailed empirical questions and obtain more rigorous results.”