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Scientists discover how faulty genetic instructions contribute to development of AML

Scientists have previously identified a series of genetic errors that commonly occur inside cancerous blood cells, but it hasn't been clear exactly how those genetic malfunctions create immature blood cells that overpopulate, crowd out healthy cells and spread in patients with acute myeloid leukemia or AML.

24 Jun 2016

University of Miami researchers awarded new contracts to detect genetic factors linked to Alzheimer's disease risk

Alzheimer's disease is the leading cause of dementia in the elderly and occurs in all ethnic and racial groups. It affects more than 5 million people age 65 and older in the United States alone and there is currently no effective treatment or cure.

24 Jun 2016

KARMA study confirms resistance to anti-malarial drugs confined to Southeast Asia

The first global mapping of artemisinin resistance has definitively confirmed that resistance to the main drug currently used in the treatment of Plasmodium falciparum malaria is for the moment confined to Southeast Asia and has not spread to sub-Saharan Africa.

24 Jun 2016

Scientists provide new insights into role of star-shaped brain cells in memory, learning

A molecule that enables strong communication between our brain and muscles appears to also aid essential communication between our neurons, scientists report.

23 Jun 2016

New optical detection technology could be effective to monitor blood-glucose levels

A newly developed method for detecting glucose based on how it absorbs a specific type of light could spell the end of the painful, invasive finger-prick tests diabetics rely on to monitor their condition, says a Texas A&M University biomedical engineer who is developing the technology.

23 Jun 2016

Lack of Alix protein leads to occurrence of hydrocephalus in the brain

A team led by researchers at St. Jude Children's Research Hospital report that mice lacking the protein Alix develop hydrocephalus or "water on the brain." Alix ensures that epithelial cells of the choroid plexus are oriented correctly with respect to one another to prevent compromise of the epithelial barrier.

23 Jun 2016

New optogenetic manipulation technique could possibly reduce migraine headaches

Despite decades of research, migraines are often not well controlled with medication. For those prone to this type of debilitating headache, it sometimes seems nothing can stop the pain and the sensitivity to light. But what if light itself was key to their relief?

23 Jun 2016

Researchers uncover new clues about role of glucosamine in early embryonic development

Most pregnant women with well-controlled diabetes give birth to healthy children. But their babies run much higher risks of birth defects than babies born to women without diabetes, because very early in embryonic development, the babies are exposed to higher levels of glucose in maternal blood.

23 Jun 2016

Sperm of smokers has greater extent of DNA damage than that of non-smokers

A recent study found that that sperm of men who smoke has a greater extent of DNA damage than that of non-smokers.

22 Jun 2016

Researchers reveal novel mechanism of smoke induced collapse of protein homeostasis in COPD

Few threats to public health are as perilous as cigarette smoking, with more than 435,000 Americans dying each year of tobacco-related pulmonary illnesses such as chronic obstructive pulmonary disease (COPD).

22 Jun 2016

Mitofusin 2 protein could serve as therapeutic target to ameliorate sarcopenia in older adults

One of the alterations that most affects the quality of life of the elderly is muscle wastage and the resulting loss of strength, a condition known as sarcopenia. At about 55 years old, people begin to lose muscle mass, this loss continues into old age, at which point it becomes critical.

22 Jun 2016

Researchers reveal DNA unwrapping can happen asymmetrically to expose specific genes

The protein complex that holds strands of DNA in compact spools partially disassembles itself to help genes reveal themselves to specialized proteins and enzymes for activation, according to Rice University researchers and their colleagues.

22 Jun 2016

New study suggests how rod photoreceptors may have originated to give rise to nocturnal mammals

Retinas from our earliest vertebrate ancestors had cone-like photoreceptors, presumably allowing them to see in daylight, but little ability to see at night. Then, millions of years ago in the Mesozoic era, and in relatively short order, mammals emerged that had retinas with predominantly rod photoreceptors, allowing for them to see at night perhaps to hunt for food while their dinosaur predators were dozing.

22 Jun 2016

Protein-based CHD risk score developed

Researchers have screened over 1000 plasma proteins to develop a predictive score in patients with stable coronary heart disease.

22 Jun 2016

Scientists uncover five new genetic causes of bowel cancer

A landmark study has given the most detailed picture yet of the genetics of bowel cancer - the UK's fourth most common cancer.

22 Jun 2016

Highly structured nutrition therapy provides substantial impact on A1C, body weight and lipid profiles

Researchers at Joslin Diabetes Center have announced the results of a study that may change how nutrition therapy is delivered to overweight and obese patients with type 2 diabetes.

22 Jun 2016

First CRISPR/Cas9 screen helps identify human proteins required for Zika virus replication

Scientists at the University of Massachusetts Medical School have performed the first CRISPR/Cas9 screen to discover human proteins that Zika virus needs for replication.

22 Jun 2016

SORLA protein makes fat cells oversensitive to insulin

SORLA is a protein that influences the balance of metabolic processes in adipose tissue, a particular form of fat. Too much of it makes fat cells overly sensitive to insulin, which leads them to break down less fat. SORLA was previously known for its protective role in Alzheimer's disease.

22 Jun 2016

Drexel University researchers aim to identify new molecular mechanisms involved in chronic pain

Chronic pain is one of the most prevalent, disabling and expensive public health crises in the United States. It affects more than 100 million Americans, with annual costs estimated at $635 billion, says a 2014 report from the American Pain Society.

22 Jun 2016

New CAR-based therapy using combined cancer target could be effective for solid tumors

Chimeric antigen receptors (CARs), engineered from a patient's own immune cells, have been successful for treating blood cancers, but using CARs for solid tumors has been limited by side effects to normal tissues containing the protein targeted by the engineered cells.

22 Jun 2016

G Protein News and Research

Scientists discover how faulty genetic instructions contribute to development of AML

University of Miami researchers awarded new contracts to detect genetic factors linked to Alzheimer's disease risk

KARMA study confirms resistance to anti-malarial drugs confined to Southeast Asia

Scientists provide new insights into role of star-shaped brain cells in memory, learning

New optical detection technology could be effective to monitor blood-glucose levels

Lack of Alix protein leads to occurrence of hydrocephalus in the brain

New optogenetic manipulation technique could possibly reduce migraine headaches

Researchers uncover new clues about role of glucosamine in early embryonic development

Sperm of smokers has greater extent of DNA damage than that of non-smokers

Researchers reveal novel mechanism of smoke induced collapse of protein homeostasis in COPD

Mitofusin 2 protein could serve as therapeutic target to ameliorate sarcopenia in older adults

Researchers reveal DNA unwrapping can happen asymmetrically to expose specific genes

New study suggests how rod photoreceptors may have originated to give rise to nocturnal mammals

Protein-based CHD risk score developed

Scientists uncover five new genetic causes of bowel cancer

Highly structured nutrition therapy provides substantial impact on A1C, body weight and lipid profiles

First CRISPR/Cas9 screen helps identify human proteins required for Zika virus replication

SORLA protein makes fat cells oversensitive to insulin

Drexel University researchers aim to identify new molecular mechanisms involved in chronic pain

New CAR-based therapy using combined cancer target could be effective for solid tumors

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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