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Israeli researchers establish novel optogenetic method for cardiac pacing and resynchronization

Israeli researchers have successfully established a new approach for pacing the heart and synchronizing its mechanical activity without the use of a conventional electrical pacemaker. This novel biologic strategy employs light-sensitive genes that can be injected into the heart and then activated by flashes of blue light.

23 Jun 2015

UT Southwestern researchers identify two proteins within fetal lungs that initiate labor process

Researchers at UT Southwestern Medical Center have identified two proteins in a fetus' lungs responsible for initiating the labor process, providing potential new targets for preventing preterm birth.

23 Jun 2015

UT Southwestern scientists devise new technique to identify cell that replenishes adult heart muscle

Regenerative medicine researchers at UT Southwestern Medical Center have identified a cell that replenishes adult heart muscle by using a new cell lineage-tracing technique they devised.

23 Jun 2015

Purdue University-led study could lead to better treatments for people infected with MERS virus

A Purdue University-led team of researchers studying the Middle East Respiratory Syndrome, or MERS, have found molecules that shut down the activity of an essential enzyme in the virus and could lead the way to better treatments for those infected.

23 Jun 2015

PSMA can be an ideal target for diagnosis and treatment of prostate cancer

Prostate-specific membrane antigen (PSMA) is a surface protein that is normally present on healthy prostate cells, but is found at much higher levels on prostate cancer cells. It is barely found in the rest of the body. "Therefore, PSMA is an ideal target for diagnostic purposes as well as targeted therapies against prostate cancer," says biotechnologist Dr. Matthias Eder of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ).

23 Jun 2015

Experimental vaccine candidate can stimulate immune system activity to prevent HIV infection

New research led by scientists at The Scripps Research Institute (TSRI), International AIDS Vaccine Initiative (IAVI) and The Rockefeller University shows in mice that an experimental vaccine candidate designed at TSRI can stimulate the immune system activity necessary to stop HIV infection. The findings could provide key information for the development of an effective AIDS vaccine.

22 Jun 2015

New research sheds light on molecular architecture of receptors linked to many brain diseases

Scientists at The Scripps Research Institute have teamed up with several other institutions and pharmaceutical companies, including the University of Southern California (USC), San Diego's Receptos Inc. and Japanese company Ono Pharmaceutical Co., Ltd., to publish the first 3D structures of a receptor implicated in many diseases of the brain and in normal physiology throughout the body.

22 Jun 2015

TSRI scientists devise powerful set of chemical methods to explore protein biology

Scientists at The Scripps Research Institute (TSRI) have devised a powerful set of chemical methods for exploring the biology of proteins.

22 Jun 2015

Hormones used in breast cancer treatment could affect disease progression, outcomes in some patients

Recently, researchers have discovered that the hormone progesterone, an ingredient in contraceptives and menopausal hormone replacement therapies, might stimulate the growth of breast cancer cells that are resistant to anti-estrogen therapy and chemotherapy.

22 Jun 2015

Planning for first clinical trial of MERS-CoV vaccine candidate now underway

Researchers from Ludwig-Maximilians-Universitaet in Munich have demonstrated, in a preclinical setting, the protective effect of a candidate vaccine directed against the coronavirus that causes Middle East Respiratory Syndrome. Planning for the first clinical trial is now underway.

22 Jun 2015

UW researchers identify how plants arrange cellular structures on their surface

In the age of tablet computers and smart phones, it's easy to feel inundated and overloaded by information. But on a cellular level, this bombardment is business as usual, and a team of University of Washington researchers has identified a mechanism that some plant cells use to receive complex and contradictory messages from their neighbors.

19 Jun 2015

Drug discovery experts receive £3m to find new treatments for Alzheimer's disease

Funding worth nearly half a million pounds will unite academics at the University of Southampton with drug discovery experts at the medical research charity MRC Technology, to target the immune system in the hunt for new treatments for Alzheimer's disease.

19 Jun 2015

Study opens new area of discovery for different aspects of cell biology, biomedical research

Every cell in the body uses phosphorylation, the process of adding a chemical tag to control a protein's function and fate, such as when it moves from one part of a cell to another or binds to other proteins.

19 Jun 2015

UNC Lineberger scientists contribute to better understanding of genetic mutations in melanoma

UNC Lineberger Comprehensive Cancer Center researchers have significantly contributed to a better understanding of the genetic alterations found in cutaneous melanoma, the most lethal form of skin cancer, as part of a multi-institution, international effort of The Cancer Genome Atlas.

19 Jun 2015

Human breast milk bought online poses serious health risks

The recent craze for human breast milk, which has become a lucrative online market, poses serious health risks, according to British experts.

19 Jun 2015

Taranis protein could hold key to a good night's sleep

Most of us need seven to eight hours of sleep a night to function well, but some people seem to need a lot less sleep. The difference is largely due to genetic variability. In research published online June 18th in Current Biology, researchers report that two genes, originally known for their regulation of cell division, are required for normal slumber in fly models of sleep: taranis and Cyclin-dependent kinase 1 (Cdk1).

19 Jun 2015

Scientists identify four melanoma subtypes that share common 'downstream' signaling pathways

Cutaneous melanoma, the most deadly form of skin cancer, is now believed to be divided into four distinct genomic subtypes, say researchers at The University of Texas MD Anderson Cancer Center, a finding that could prove valuable in the ever-increasing pursuit of personalized medicine.

19 Jun 2015

Preventing neutrophils from producing NETs can accelerate wound healing in diabetic mice

One of the body's tools for fighting off infection in a wound may actually slow down the healing process, according to new research by a team of Harvard University, Boston Children's Hospital, and Penn State University scientists.

19 Jun 2015

Three studies describe advances toward development of antibodies to stop HIV

A trio of studies being published today in the journals Science and Cell describes advances toward the development of an HIV vaccine. The three study teams all demonstrated techniques for stimulating animal cells to produce antibodies that either could stop HIV from infecting human cells in the laboratory or had the potential to evolve into such antibodies.

19 Jun 2015

Automated droplet-based surface sampling probe analyzes liver biopsy sample in 10 minutes

Surgeons could know while their patients are still on the operating table if a tissue is cancerous, according to researchers from the Department of Energy's Oak Ridge National Laboratory and Brigham and Women's Hospital/Harvard Medical School.

19 Jun 2015

Protein C News and Research

Israeli researchers establish novel optogenetic method for cardiac pacing and resynchronization

UT Southwestern researchers identify two proteins within fetal lungs that initiate labor process

UT Southwestern scientists devise new technique to identify cell that replenishes adult heart muscle

Purdue University-led study could lead to better treatments for people infected with MERS virus

PSMA can be an ideal target for diagnosis and treatment of prostate cancer

Experimental vaccine candidate can stimulate immune system activity to prevent HIV infection

New research sheds light on molecular architecture of receptors linked to many brain diseases

TSRI scientists devise powerful set of chemical methods to explore protein biology

Hormones used in breast cancer treatment could affect disease progression, outcomes in some patients

Planning for first clinical trial of MERS-CoV vaccine candidate now underway

UW researchers identify how plants arrange cellular structures on their surface

Drug discovery experts receive £3m to find new treatments for Alzheimer's disease

Study opens new area of discovery for different aspects of cell biology, biomedical research

UNC Lineberger scientists contribute to better understanding of genetic mutations in melanoma

Human breast milk bought online poses serious health risks

Taranis protein could hold key to a good night's sleep

Scientists identify four melanoma subtypes that share common 'downstream' signaling pathways

Preventing neutrophils from producing NETs can accelerate wound healing in diabetic mice

Three studies describe advances toward development of antibodies to stop HIV

Automated droplet-based surface sampling probe analyzes liver biopsy sample in 10 minutes

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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