Genes News and Research

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Discovery of new area for exploration of schizophrenia

Schizophrenia may occur, in part, because of a problem in an intermittent on/off switch for a gene involved in making a key chemical messenger in the brain, scientists have found in a study of human brain tissue.

17 Oct 2007

Genetic contributions to human brain morphology and intelligence

While showing an impressive growth prenatally, the human brain is not completed at birth.

17 Oct 2007

Contraceptive pill with no side-effects in the pipeline

Scientists in the United States are developing a new contraceptive pill with no side-effects.

17 Oct 2007

Dmp1 gene and lung cancer

The first research to show the involvement of a gene known as Dmp1 in human lung cancer will hopefully lead to an increased understanding on what goes wrong at the cellular level to cause the disease, according to researchers from Wake Forest University School of Medicine reporting in Cancer Cell .

16 Oct 2007

Newly solved structure reveals how cells resist oxygen damage

The sun's rays give life, but also take it away. Singlet oxygen, a byproduct of the photosynthetic process by which certain cells convert sunlight into energy, is a highly toxic and reactive substance that tears cells apart.

16 Oct 2007

New active compound for the treatment of malaria

Malaria is caused by Plasmodium parasites and it is the female Anopheles mosquito that acts as a vector for these malarial parasites in to the human body.

16 Oct 2007

Direct selection of human genomic loci by microarray hybridization

Researchers at Baylor College of Medicine and Roche NimbleGen Inc., a fully integrated part of Roche Applied Science, have published details of a highly efficient and cost-effective method for capturing targeted regions of the genome via NimbleChip microarrays in preparation for high-throughput 454 Sequencing.

16 Oct 2007

New insight into Herceptin resistance in breast cancer

A new study provides important insight into the mechanisms involved in resistance to treatment of breast cancer patients with trastuzumab (Herceptin). The research, published by Cell Press in the October issue of the journal Cancer Cell , identifies markers that may help to identify patients who are unlikely to respond to trastuzumab treatment and provides a potential strategy for treating these patients.

16 Oct 2007

Enhanced DNA-repair mechanism can cause breast cancer

Although defects in the "breast cancer gene," BRCA1, have been known for years to increase the risk for breast cancer, exactly how it can lead to tumor growth has remained a mystery.

16 Oct 2007

Depression among patients with coronary artery disease

Depression has long had a popular link to cardiovascular disease and death. However, only during the last 15 years scientific evidence supporting this common wisdom has been available (Glassman et al., 2007a).

16 Oct 2007

Hooked on chocolate? the answer why may lie in your gut

For the first time, scientists have linked the all-too-human preference for a food - chocolate - to a specific, chemical signature that may be programmed into the metabolic system and is detectable by laboratory tests.

15 Oct 2007

Important insights into blood vessel formation

Researchers have identified a molecular pathway that plays a critical role in the growth of blood vessels.

15 Oct 2007

Familial multiple sclerosis appears more severe than non-familial

Magnetic resonance images (MRI) of a large group of patients with multiple sclerosis has provided the first evidence that those with a history of MS in their families show more severe brain damage than patients who have no close relatives with the disease.

15 Oct 2007

How does the opioid system work?

The opioid system controls pain, reward and addictive behaviors. Opioids exert their pharmacological actions through three opioid receptors, mu, delta and kappa whose genes have been cloned (Oprm, Oprd1 and Oprk1, respectively).

15 Oct 2007

New gene findings show that controls of lifespan and cancer have deep, common roots

A person is 100 times more likely to get cancer at age 65 than at age 35. But new research reported in the journal "Nature Genetics" identifies naturally occurring processes that allow many genes to both slow aging and protect against cancer in the much-studied C. elegans roundworm.

15 Oct 2007

People with lower dopamine levels eat more

Science has found one likely contributor to the way that some folks eat to live and others live to eat.

15 Oct 2007

Dopamine levels and appetite

Science has found one likely contributor to the way that some folks eat to live and others live to eat.

15 Oct 2007

Improving working memory by computerized strategy in ADHD

Attention-deficit/hyperactivity disorder (ADHD), a state of serious impairments in both learning ability and social functioning, is one of many labels for one of the most prevalent conditions in child psychiatry, and, undoubtedly, the most controversial, which partly persists into adulthood.

15 Oct 2007

RNA-binding protein key to understanding myotonic dystrophy type 1

Increased levels of a protein called CUGBP1 play an important role in the adult-onset form of muscular dystrophy called myotonic dystrophy type 1, said Baylor College of Medicine researchers in a report that appears in the journal Molecular Cell.

12 Oct 2007