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DNDi awarded USAID grant to develop new treatments for river blindness, elephantiasis

The Drugs for Neglected Diseases initiative has been awarded US$ 10 million by the United States Agency for International Development to develop new treatments for onchocerciasis (river blindness) and lymphatic filariasis (elephantiasis) - the first-ever USAID grant for neglected tropical disease research and development (R&D).

17 Dec 2014

Researchers examining new antioxidant-based therapeutic approaches to hypertension

High blood pressure affects more than 70 million Americans and is a major risk factor for stroke, heart failure and other renal and cardiovascular diseases. Two University of Houston College of Pharmacy researchers are examining the role of intrinsic antioxidant pathways in mitigating hypertension.

17 Dec 2014

Study finds link between contraband cigarette and illicit drug use among teens in Canada

A University of Alberta economics professor has discovered a link between contraband cigarette use and illicit drug use among Canadian teens.

17 Dec 2014

Two UT Arlington professors named National Academy of Inventors Fellows

Two University of Texas at Arlington professors known for their innovation in the world of chemistry have been named Fellows of the National Academy of Inventors.

17 Dec 2014

Stuttgart scientists reveal current state of research on catalytic micro- and nanomotors

At least since the movie “The Fantastic Voyage” in 1966, in which a submarine is shrunk down and injected into the blood stream of a human, people have been toying with the idea of sending tiny “micromachines” and “nanorobots” into our organs or individual cells to carry out delicate “repairs”.

17 Dec 2014

Mitochondrial DNA may predict overall risk of frailty, death

New research from The Johns Hopkins University suggests that the amount of mitochondrial DNA (mtDNA) found in peoples’ blood directly relates to how frail they are medically. This DNA may prove to be a useful predictor of overall risk of frailty and death from any cause 10 to 15 years before symptoms appear.

17 Dec 2014

Lilly receives FDA approval for CYRAMZA (ramucirumab)

Eli Lilly and Company has received its third U.S. Food and Drug Administration approval for CYRAMZA (ramucirumab).

16 Dec 2014

Preclinical study strongly supports NT-113 as potential new treatment for glioblastoma multiforme

NewGen Therapeutics, Inc. today announced the publication of preclinical research strongly supporting NT-113, the company's novel irreversible pan-erbB inhibitor (EGFR, HER2 and HER4), as a potential new treatment for glioblastoma multiforme (GBM), the most common and most aggressive malignant primary brain tumor in adults.

16 Dec 2014

Isis Pharmaceuticals begins ISIS-DMPK Rx clinical study in DM1 patients

Isis Pharmaceuticals, Inc. announced today that it has initiated a study for ISIS-DMPK Rx in patients with Myotonic Dystrophy Type 1 (DM1). DM1 is a rare genetic neuromuscular disease caused by the production of toxic dystrophia myotonica-protein kinase (DMPK) RNA in cells. ISIS-DMPKRx is specifically designed to reduce toxic DMPK RNA.

16 Dec 2014

Pre-clinical studies confirm TRXE-009 as new potential treatment for melanoma

Novogen Limited, Australian/US biotechnology company, today announces that it has confirmed that its lead candidate product, TRXE-009, originally developed for the treatment of brain cancers, has been shown in pre-clinical studies also to be highly active against melanoma.

16 Dec 2014

CARLINA, Atlangram partner to develop antibiotics for osteoarticular infectious diseases

CARLINA Technologies, a biotechnology company specializing in the development of nanomedicines, today announces the signing of a partnership agreement with Atlangram for the development of innovative pharmaceutical forms of antibiotics for the targeting of osteoarticular infectious diseases.

16 Dec 2014

Researchers discover widespread misconception about antibiotic resistance among patients

Over prescription of antibiotics is a major factor driving one of the biggest public health concerns today: antibiotic resistance. In a first-of-its-kind study, research led by the George Washington University suggests that public health educational materials may not address the misconceptions that shape why patients expect antibiotics, driving doctors to prescribe them more.

16 Dec 2014

Survey reveals use of 'fake weed' among college students

A survey of more than 300 college students reveals that college students who use "fake weed" or synthetic THC are most likely to have tried the drug because they were curious. Rebecca Vidourek, a University of Cincinnati assistant professor of health promotion and assistant director of the Center for Prevention Science; Keith King, a UC professor of health promotion and director of the Center for Prevention Science; and Michelle Burbage, a graduate student and graduate assistant for UC's Health Promotion and Education Program, published their findings in the current issue of the Journal of Drug Education.

16 Dec 2014

National survey shows decrease in alcohol, cigarette and illicit drug use among U.S. teens

A national survey of students in U.S. middle schools and high schools shows some important improvements in levels of substance use.

16 Dec 2014

Dartmouth research opens way for industrial applications of nanotechnology

Dartmouth researchers have found a solution using visible light to reduce waste produced in chemically activated molecular switches, opening the way for industrial applications of nanotechnology ranging from anti-cancer drug delivery to LCD displays and molecular motors.

16 Dec 2014

Joslin study could lead to improved anti-aging drugs

In a study published today by Nature, researchers at Joslin Diabetes Center used a microscopic worm (C. elegans) to identify a new path that could lead to drugs to slow aging and the chronic diseases that often accompany it--and might even lead to better cosmetics.

16 Dec 2014

Sensitive toxicity test aims to detect dangerous side effects in pharmaceutical development

Because of undetected toxicity problems, about a third of prescription drugs approved in the U.S. are withdrawn from the market or require added warning labels limiting their use. An exceptionally sensitive toxicity test invented at the University of Utah could make it possible to uncover more of these dangerous side effects early in pharmaceutical development so that fewer patients are given unsafe drugs.

16 Dec 2014

TSRI scientists awarded $2.3 million grant to find ways to erase traumatic memories

Scientists from the Florida campus of The Scripps Research Institute have been awarded $2.3 million from the Department of Health and Human Services of the National Institutes of Health to better understand how memories are stored in the hopes of eventually being able to treat posttraumatic stress disorder (PTSD) by erasing traumatic memories without altering other, more benign ones.

16 Dec 2014

UT Southwestern researchers identify cell signaling mechanism that plays vital role in brain cancer

UT Southwestern Medical Center neurology researchers have identified an important cell signaling mechanism that plays an important role in brain cancer and may provide a new therapeutic target.

16 Dec 2014

Novartis announces FDA approval of Signifor LAR for treatment of patients with acromegaly

Novartis announced today that the US Food and Drug Administration has approved Signifor long-acting release (LAR) (pasireotide) for injectable suspension, for intramuscular use, for the treatment of patients with acromegaly who have had an inadequate response to surgery and/or for whom surgery is not an option.

16 Dec 2014

Drugs News and Research

DNDi awarded USAID grant to develop new treatments for river blindness, elephantiasis

Researchers examining new antioxidant-based therapeutic approaches to hypertension

Study finds link between contraband cigarette and illicit drug use among teens in Canada

Two UT Arlington professors named National Academy of Inventors Fellows

Stuttgart scientists reveal current state of research on catalytic micro- and nanomotors

Mitochondrial DNA may predict overall risk of frailty, death

Lilly receives FDA approval for CYRAMZA (ramucirumab)

Preclinical study strongly supports NT-113 as potential new treatment for glioblastoma multiforme

Isis Pharmaceuticals begins ISIS-DMPK Rx clinical study in DM1 patients

Pre-clinical studies confirm TRXE-009 as new potential treatment for melanoma

CARLINA, Atlangram partner to develop antibiotics for osteoarticular infectious diseases

Researchers discover widespread misconception about antibiotic resistance among patients

Survey reveals use of 'fake weed' among college students

National survey shows decrease in alcohol, cigarette and illicit drug use among U.S. teens

Dartmouth research opens way for industrial applications of nanotechnology

Joslin study could lead to improved anti-aging drugs

Sensitive toxicity test aims to detect dangerous side effects in pharmaceutical development

TSRI scientists awarded $2.3 million grant to find ways to erase traumatic memories

UT Southwestern researchers identify cell signaling mechanism that plays vital role in brain cancer

Novartis announces FDA approval of Signifor LAR for treatment of patients with acromegaly

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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