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Johns Hopkins researchers reveal neuronal cell survival mechanism

Nerve cells that regulate everything from heart muscle to salivary glands send out projections known as axons to their targets. By way of these axonal processes, neurons control target function and receive molecular signals from targets that return to the cell body to support cell survival. Now, Johns Hopkins researchers have revealed a molecular mechanism that allows a signal from the target to return to the cell body and fulfill its neuron-sustaining mission.

31 Aug 2011

Patients with coronary artery disease more likely to have complications from orthopedic surgery

Thrombotic and bleeding events are complications that may occur after surgery. With the aging population in the western world, there are more patients undergoing orthopedic surgery than ever before. This makes understanding the risk of complications from orthopedic surgery exceedingly important. However, there is a lack of data investigating the incidence of thrombotic and bleeding complications in orthopedic surgery.

31 Aug 2011

Positive results from Bionovo's Menerba tolerability trial on menopausal hot flashes

Bionovo, Inc., a pharmaceutical company focused on the discovery and development of safe and effective treatments for women's health and cancer, today announced the positive results from the completion of their tolerability trial of Menerba (MF101) for menopausal hot flashes.

31 Aug 2011

Stent for Life Initiative aims to support implementation of primary PCI in the ESC countries

Primary PCI is the best reperfusion therapy for patients presenting with acute ST-elevation myocardial infarction. CJ Terkelsen and co-workers used the Western Denmark Heart Registry to describe the implementation of primary PCI in Denmark.

30 Aug 2011

CMR predicts increased risk of sudden cardiac death in patients with myocardial infarction

Universitätsmedizin Berlin and Universität Leiden developed a method to identify a subgroup of patients with myocardial infarction that is at increased risk for sudden cardiac death.

30 Aug 2011

Postoperative outcomes of VAD bridged patients are worse than conventional therapy

Postoperative outcomes of severe heart failure patients bridged with short-term VADs to urgent heart transplantation are significantly worse than those of patients bridged with conventional support, recent data of the Spanish National Heart Transplant Registry suggest.

30 Aug 2011

Daily remote ICD monitoring a safe alternative to conventional follow-up

Device management using a home monitoring system with daily telemetry in patients with ICDs is a safe alternative to conventional monitoring and could decrease the number of inappropriate shocks, according to results of the ECOST study, a multicentre randomised trial performed in France.

30 Aug 2011

Balloon pump use prior to PCI does not reduce infarct size in STEMI patients without shock

Intra-aortic balloon pump counterpulsation prior to PCI in patients with ST segment elevation MI does not reduce infarct size as measured by MRI, according to results from the Counterpulsation Reduces Infarct Size Acute Myocardial Infarction (CRISP AMI) trial.

30 Aug 2011

Intra-aortic balloon counterpulsation prior to PCI does not reduce infarct size in AMI patients

Inserting intra-aortic balloon pumps prior to angioplasty in patients with acute myocardial infarction (AMI) does not reduce the scope of heart muscle damage, a condition referred to as infarct size, according to a new study conducted by Duke University Medical Center researchers.

30 Aug 2011

An advance toward using stem cells in 'regenerative medicine'

With stem cells so fickle and indecisive that they make Shakespeare's Hamlet pale by comparison, scientists today described an advance in encouraging stem cells to make decisions about their fate.

30 Aug 2011

Educational program about cardiovascular prevention in children can reduce parents' CVD risk

"A multidisciplinary educational programme in cardiovascular prevention directed to children of school age can reduce their parents' cardiovascular risk. Cardiovascular prevention could have more success focusing on children first, inducing healthier lifestyle habits in the whole family, "said investigator Luciana Fornari, from the University of Sao Paulo, Brazil.

30 Aug 2011

New chemical compounds show promise against set of protein-folding diseases

Collaborating researchers at Stanford University and The Scripps Research Institute have identified chemical compounds that show promise as potential therapeutics for a set of medical conditions caused by the abnormal clumping together of a protein known as transthyretin.

30 Aug 2011

Study indicates large gap in use of proven therapies for heart attack or stroke

A global study in 17 countries led by McMaster University researchers has found too few patients are using drugs proven to give significant benefits in warding off a heart attack or stroke.

30 Aug 2011

Researchers demonstrate benefits of 8-week 'Beating Heart Problems' group programme

Researchers from the Heart Research Centre in Melbourne, Australia, have demonstrated the benefits of the 8-week 'Beating Heart Problems' group programme in a randomised controlled trial.

30 Aug 2011

Study finds higher incidence of arrhythmias in elite cross-country skiers

A Swedish study presented at the ESC Congress 2011 today, found a higher incidence of arrhythmias in cross-country skiers with a long history of endurance training.

30 Aug 2011

St. Michael's Echocardiography and Vascular Laboratory receives ICAEL accreditation

The Echocardiography and Vascular Laboratory at St. Michael's Hospital has been recognized for its commitment to quality patient care and testing for heart and vascular disease.

30 Aug 2011

Ivabradine reduces heart volume among patients with cardiac insufficiency

As guest speaker at the European Society of Cardiology's Congress currently under way in Paris, Dr. Jean-Claude Tardif, Director of the Montreal Heart Institute's Research Centre and professor of medicine at the Universit- de Montr-al, today presented the results of an analysis demonstrating that ivabradine, a medication used to reduce heart rate, also reduces heart volume (left ventricle) among patients with cardiac insufficiency.

30 Aug 2011

Bristol Meyer Squibb’s new blood thinner drug for stroke prevention

Researchers find that an experimental anticlotting pill Eliquis is more effective than standard drug, warfarin, at preventing strokes in people with a heart condition that puts them at high risk of blood clots and stroke. The new drug also known as apixaban, cut the risk of stroke by 21% compared with warfarin in people with atrial fibrillation (AF). It lowered the risk of dying by 11%.

30 Aug 2011

Chocolate for the heart - benefits revealed

A comprehensive analysis of previous studies including more than 114,000 subjects has shown that high levels of chocolate consumption are associated with a significant reduction in the risk of certain cardiovascular disorders.

30 Aug 2011

Specific inhibitor of microRNA-100 can stimulate development of new blood vessels

A specific inhibitor of the small regulatory RNA-molecule "microRNA-100" can be used to stimulate the growth of new blood vessels, if a major artery is chronically occluded.

29 Aug 2011

Heart News and Research

Johns Hopkins researchers reveal neuronal cell survival mechanism

Patients with coronary artery disease more likely to have complications from orthopedic surgery

Positive results from Bionovo's Menerba tolerability trial on menopausal hot flashes

Stent for Life Initiative aims to support implementation of primary PCI in the ESC countries

CMR predicts increased risk of sudden cardiac death in patients with myocardial infarction

Postoperative outcomes of VAD bridged patients are worse than conventional therapy

Daily remote ICD monitoring a safe alternative to conventional follow-up

Balloon pump use prior to PCI does not reduce infarct size in STEMI patients without shock

Intra-aortic balloon counterpulsation prior to PCI does not reduce infarct size in AMI patients

An advance toward using stem cells in 'regenerative medicine'

Educational program about cardiovascular prevention in children can reduce parents' CVD risk

New chemical compounds show promise against set of protein-folding diseases

Study indicates large gap in use of proven therapies for heart attack or stroke

Researchers demonstrate benefits of 8-week 'Beating Heart Problems' group programme

Study finds higher incidence of arrhythmias in elite cross-country skiers

St. Michael's Echocardiography and Vascular Laboratory receives ICAEL accreditation

Ivabradine reduces heart volume among patients with cardiac insufficiency

Bristol Meyer Squibb’s new blood thinner drug for stroke prevention

Chocolate for the heart - benefits revealed

Specific inhibitor of microRNA-100 can stimulate development of new blood vessels

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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