G Protein News and Research

RSS

Molecular map of transporter proteins could be vital step toward drug discovery against zinc-related diseases

Mapping the molecular structure where medicine goes to work is a crucial step toward drug discovery against deadly diseases.

21 Jun 2016

New protein risk score may help predict cardiovascular risk in patients with CHD

In a study appearing in the June 21 issue of JAMA, Peter Ganz, M.D., of the University of California-San Francisco, and colleagues conducted a study to develop and validate a score to predict risk of cardiovascular outcomes among patients with coronary heart disease using analysis of circulating proteins.

21 Jun 2016

Potential therapeutic approaches to combat chronic myeloid leukemia

Chronic myeloid leukemia (CML) develops through chromosomal alterations in blood-forming cells of the bone marrow and usually occurs in older persons. Around 20 percent of adults diagnosed with leukemia suffer from this type of blood cancer.

21 Jun 2016

Researchers identify new myosin kinase that could optimize heart contractions

The heart is the only muscle that contracts and relaxes continuously over a lifetime to pump oxygen-rich blood to the body's organs. Researchers at UT Southwestern Medical Center now have identified a previously unrecognized enzyme that could optimize contraction and lead to new strategies to treat heart failure.

21 Jun 2016

Long-term opioid therapy may not be effective to manage pain in sickle cell disease patients

In a small study looking at pain assessments in adults with sickle cell disease, researchers at Johns Hopkins says overall, those treated long-term with opioids often fared worse in measures of pain, fatigue and curtailed daily activities than those not on long-term opioids.

21 Jun 2016

Scientists aim to explore how gestational diabetes can put babies at lifelong risk for cardiovascular disease

Gestational diabetes can put babies at a lifelong risk for cardiovascular disease, and scientists want to better understand how.

21 Jun 2016

Breast cancer cells use new signaling pathway to cope with lack of oxygen levels inside tumors

Researchers have identified a new signaling pathway that helps cancer cells cope with the lack of oxygen found inside tumors. These are the results of a study published in Nature Cell Biology on June 20, and led by researchers at NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center, Princess Margaret Cancer Center, the University of Toronto, Harvard Medical School and Oxford University.

21 Jun 2016

New blood test could help predict severity of pulmonary arterial hypertension

Johns Hopkins Medicine researchers report that rising blood levels of a protein called hematoma derived growth factor (HDGF) are linked to the increasing severity of pulmonary arterial hypertension, a form of damaging high blood pressure in the lungs.

20 Jun 2016

TUM researchers uncover molecular mechanism of thalidomide

In the 1950s, thalidomide (Contergan) was prescribed as a sedative drug to pregnant women, resulting in a great number of infants with serious malformations. Up to now, the reasons for these disastrous birth defects have remained unclear.

20 Jun 2016

Study suggests how expression, function of nAChRs regulated in AD

Nicotinic acetylcholine receptors (nAChRs) have been pursued for decades as potential molecular targets to treat cognitive dysfunction in Alzheimer's disease (AD) due to their demonstrated role in processes underlying cognition such as synaptic facilitation, and theta and gamma wave activity.

20 Jun 2016

Scientists study fundamentals of tumour surveillance by immune system in mice models

The body's defences detect and eliminate not only pathogens but also tumour cells. Natural killer cells (NK-Cells) are specifically activated by chemical messengers, the Cytokines, to seek and destroy tumour cells.

20 Jun 2016

Researchers uncover mechanism of two-in-one sensor protein KdpD

Uptake of potassium by bacteria is regulated by a single protein that senses the concentration of this cation both inside the cell and in the external medium, and controls the expression of the corresponding transport protein accordingly.

20 Jun 2016

Researchers uncover potential therapeutic benefit of PI3K protein in PanNETs

Researchers from the 'Angiogenesis signaling pathways' research group of the Institute of Biomedical Investigation of Bellvitge, led by Dr. Mariona Graupera, have unveiled the potential therapeutic benefit of a selective inhibitior of the PI3-kinase (PI3K) protein in pancreatic neuroendocrine tumors (PanNETs).

17 Jun 2016

G Protein News and Research

Molecular map of transporter proteins could be vital step toward drug discovery against zinc-related diseases

New protein risk score may help predict cardiovascular risk in patients with CHD

Potential therapeutic approaches to combat chronic myeloid leukemia

Researchers identify new myosin kinase that could optimize heart contractions

Long-term opioid therapy may not be effective to manage pain in sickle cell disease patients

Scientists aim to explore how gestational diabetes can put babies at lifelong risk for cardiovascular disease

Breast cancer cells use new signaling pathway to cope with lack of oxygen levels inside tumors

New blood test could help predict severity of pulmonary arterial hypertension

TUM researchers uncover molecular mechanism of thalidomide

Study suggests how expression, function of nAChRs regulated in AD

Scientists study fundamentals of tumour surveillance by immune system in mice models

Researchers uncover mechanism of two-in-one sensor protein KdpD

Researchers uncover potential therapeutic benefit of PI3K protein in PanNETs

Elevated levels of CXCL10 protein could help diagnose cGvHD in blood, bone marrow transplant patients

Knocking out genes in E. coli affects stiffness, integrity of bacterial envelope

New research helps better understand role of TIP60 in allowing tumors to survive in low-oxygen environments

Mother's obesity can impair health of future generations

Study finds link between chronic inflammation and premenstrual symptoms

Tumour protein TP53 can locate DNA targets autonomously to prevent cancer

Innovative computer HIV capsid model provides real insight into virus maturation process

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer

Latest News