Neuroscience News and Research

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Phase 2 clinical trial of DS-1211 begins for individuals with Pseudoxanthoma Elasticum

A Phase 2 clinical trial has started of DS-1211 in individuals with Pseudoxanthoma Elasticum (PXE), a rare multisystem genetic disease that causes calcium deposits in soft tissue resulting in considerable morbidity.

1 Dec 2022

Hyperactivated brain cells following social trauma impair social reward and promote social avoidance

Past social trauma is encoded by a population of stress/threat-responsive brain cells that become hyperactivated during subsequent interaction with non-threatening social targets. As a consequence, previously rewarding social targets are now perceived as social threats, which promotes generalized social avoidance and impaired social reward processing that can contribute to psychiatric disorders, according to a study conducted by researchers at the Brain and Body Research Center at Mount Sinai and published November 30 in Nature.

30 Nov 2022

INPP5D gene plays key role in enabling microglial cells to prevent plaque buildup

A change in the DNA code (mutation) of a gene that plays a key role in the brain's immune defenses may prevent related cells from clearing away protein-filled clumps, a new study in mice shows.

30 Nov 2022

Study reveals key details of how DREADD technology highjacks neuronal activity

Understanding of how neuronal activity modulates brain function is a key first step towards creating more effective drugs to treat a variety of neuropsychiatric illnesses, including depression, anxiety, schizophrenia, substance abuse, epilepsy, and others.

30 Nov 2022

Research findings may offer a new potential therapeutic target for Alzheimer’s disease

A new study links a gene concentrated in the brain's cleanup cells, known as microglia, to the inflammation that has increasingly emerged as a key mechanism contributing to Alzheimer's disease.

30 Nov 2022

Study identifies a urinary biomarker to reveal early-stage Alzheimer’s disease

Could a simple urine test reveal if someone has early-stage Alzheimer’s disease and could this pave the way for large-scale screening programs? A new study in Frontiers in Aging Neuroscience certainly suggests so. The researchers tested a large group of patients with Alzheimer’s disease of different levels of severity and healthy controls with normal cognition to identify differences in urinary biomarkers.

30 Nov 2022

Aptamer Group opens new facilities to meet the increasing demand for Optimer technology

Aptamer Group plc, the developer of novel Optimer® binders to enable innovation in the life sciences industry, announces that it has opened its new facilities in York Science Park, UK, that will enable it to meet the increasing demand for Optimer technology.

From Aptamer Group 30 Nov 2022

Unique scaffolding material shows significant promise in the treatment of spinal cord injury

Unique new material developed at University of Limerick in Ireland has shown significant promise in the treatment of spinal cord injury.

29 Nov 2022

Understanding the genetics of healthy brain cells to target vulnerabilities in glioblastomas

Understanding how cancer cells evolve from healthy brain cells and evade treatment could open up potential new drug therapies for glioblastomas, one of the most common and lethal brain cancers, new research has revealed.

29 Nov 2022

Georgia State researcher receives $1.93 million NIH award to study visual processing

Jordan Hamm, an assistant professor of neuroscience at Georgia State University, has received a five-year, $1.93 million award from the National Eye Institute at the National Institutes of Health.

28 Nov 2022

Cannabis studies receive significant media coverage regardless of the clinical outcome

In cannabis trials against pain, people who take placebos report feeling largely the same level of pain relief as those who consume the active cannabinoid substance.

28 Nov 2022

Machine learning pinpoints the most accurate timelines for predicting Alzheimer's progression

A Cornell-led collaboration used machine learning to pinpoint the most accurate means, and timelines, for anticipating the advancement of Alzheimer's disease in people who are either cognitively normal or experiencing mild cognitive impairment.

28 Nov 2022

Using human iPSC-derived cells to revolutionize the field of neurodegenerative disease

In this interview, we speak to Axol Bioscience about their human iPSC-derived cells and how they have the potential to revolutionize the field of neurodegenerative disease.

From Axol Bioscience Ltd 28 Nov 2022

People who belong to blood group Rh(D) have elevated risk of parvovirus infection

The risk of being infected by parvovirus is elevated in those people who have blood group Rh(D), according to a study published in The Journal of Infectious Diseases by researchers from Karolinska Institutet in Sweden in collaboration with Octapharma.

25 Nov 2022

Astrocytes in the brains of epileptic mice exhibit an acid response with intensified seizures

Researchers at Tohoku University have shown that astrocytes in the mouse brain exhibit an acid response with intensified epileptic seizures.

25 Nov 2022

Fossils of a tiny sea creature solve century-old debate over brain evolution in arthropods

Fossils of a tiny sea creature that died more than half a billion years ago may compel a science textbook rewrite of how brains evolved.

24 Nov 2022

New CRISPR-based tool can snip out faulty genes and replace them with new ones

Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and replace them with new ones, in a safer and more efficient way.

24 Nov 2022

Study provides a key link between the social environment and healthy brains

As people age, maintaining a positive and predictable social environment becomes more and more important. For instance, keeping close ties with friends and family has been identified as one of the key ingredients to healthy aging.

24 Nov 2022

Study finds high rate of first-onset depression during the pandemic

A new, large-scale study of more than 20,000 older adults in Canada found that approximately 1 in 8 older adults developed depression for the first time during the pandemic.

24 Nov 2022

VTC scientist wins $2.7 million to investigate viral infection of the heart that can cause sudden death

James Smyth, associate professor at the Fralin Biomedical Research Institute at VTC, has been awarded a five-year, $2.7 million grant from the National Institutes of Health to discover why viruses that normally infect our lungs can turn deadly when they infect the heart.

23 Nov 2022

Neuroscience News and Research

Phase 2 clinical trial of DS-1211 begins for individuals with Pseudoxanthoma Elasticum

Hyperactivated brain cells following social trauma impair social reward and promote social avoidance

INPP5D gene plays key role in enabling microglial cells to prevent plaque buildup

Study reveals key details of how DREADD technology highjacks neuronal activity

Research findings may offer a new potential therapeutic target for Alzheimer’s disease

Study identifies a urinary biomarker to reveal early-stage Alzheimer’s disease

Aptamer Group opens new facilities to meet the increasing demand for Optimer technology

Unique scaffolding material shows significant promise in the treatment of spinal cord injury

Understanding the genetics of healthy brain cells to target vulnerabilities in glioblastomas

Georgia State researcher receives $1.93 million NIH award to study visual processing

Cannabis studies receive significant media coverage regardless of the clinical outcome

Machine learning pinpoints the most accurate timelines for predicting Alzheimer's progression

Using human iPSC-derived cells to revolutionize the field of neurodegenerative disease

People who belong to blood group Rh(D) have elevated risk of parvovirus infection

Astrocytes in the brains of epileptic mice exhibit an acid response with intensified seizures

Fossils of a tiny sea creature solve century-old debate over brain evolution in arthropods

New CRISPR-based tool can snip out faulty genes and replace them with new ones

Study provides a key link between the social environment and healthy brains

Study finds high rate of first-onset depression during the pandemic

VTC scientist wins $2.7 million to investigate viral infection of the heart that can cause sudden death

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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