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SARS-CoV-2 Delta saliva viral load 15 times that of the wild type

Researchers hypothesize that a higher viral load of SARS-CoV-2 Delta variant in saliva contributes to its high transmissibility.

6 Dec 2021

Systematic review: The involvement of bitter taste receptors in cancer

Humans have 25 different types of functional bitter taste receptors. These are found on our tongue, where they facilitate the taste perception of bitter tasting compounds. In addition, there are increasing findings that cells of extra-oral organs also have such receptors.

4 Dec 2021

Risk of COVID-19 hospitalization among children with markers of uncontrolled asthma

The paper describes a national cohort study including all children in Scotland between the ages of 5 and 17 years who were part of the Early Pandemic Evaluation and Enhanced Surveillance of COVID-19 (EAVE II).

3 Dec 2021

New California law eases aid-in-dying process

During her three-year battle with breast cancer, my wife, Leslie, graciously endured multiple rounds of horrifically toxic treatment to eke out more time with our two young children.

3 Dec 2021

Natural triterpenoids in licorice found to inhibit SARS-CoV-2

In new studies, researchers concluded that licorice triterpenoids could be candidates for anti-SARS-CoV-2 drug developments.

2 Dec 2021

Conservative justices seem poised to overturn Roe’s abortion rights

A newly conservative Supreme Court on Wednesday heard the most serious legal challenge in a generation to a woman's right to obtain an abortion. And judging from the questions asked by the justices, it appeared possible — even likely — that a majority of them could vote to turn the thorny question of whether to allow abortion and under what circumstances back to individual states.

1 Dec 2021

Impact of SARS-CoV-2 on oral health

New research examined SARS-CoV-2 and its impact on oral health and suggests that survival against the infection may be partially dependent on such factors.

1 Dec 2021

Teriflunomide tempers lesion growth in pediatric patients with multiple sclerosis

There are few treatment options for children with multiple sclerosis - a condition in which the immune system attacks the protective covering of nerves in the brain and spinal cord - and most therapies for the disease have not been tested in children.

30 Nov 2021

Omicron and other coronavirus variants: What you need to know

Americans, already weary of a pandemic nearly two years long, were dealt a new blow during the long Thanksgiving weekend: the announcement that a new coronavirus variant had emerged.

30 Nov 2021

Study finds atazanavir inhibits main SARS-CoV-2 protease

Research shows that ATV has different antiviral activity compared to PAXLOVID™, encouraging further research.

29 Nov 2021

Persistent opioid use among 12% of patients after cardiac implantable electronic device procedures

About 12 percent of patients who receive implantable cardiac devices such as a pacemaker or defibrillator and fill an opioid prescription after surgery will consistently use the pain medication in the months afterward, raising the potential for addiction following these common procedures and identifying another pathway that could contribute to the national opioid crisis, according to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania.

26 Nov 2021

Prevalence of menstrual changes following vaccination against COVID-19

A new study investigates the relationship between COVID-19 vaccination and menstrual cycle disturbances.

26 Nov 2021

Combination of two targeted drugs shows "clinically meaningful" activity in some malignant brain tumors

A combination of two targeted cancer drugs showed unprecedented, "clinically meaningful" activity in patients with highly malignant brain tumors that carried a rare genetic mutation, according to a clinical trial report by investigators from Dana-Farber Cancer Institute.

25 Nov 2021

Direct-acting antivirals for HCV-related hepatocellular carcinoma reduces the risk of tumor progression

In a new cohort study of patients with hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC), a disease with a high recurrence rate, researchers at the Osaka City University Graduate School of Medicine reported that after receiving cancer treatment, the oral administration of direct-acting antivirals (DAA) reduces the risk of tumor progression following recurrence of the liver disease.

25 Nov 2021

Researchers analyze live bacteria from cystic lesions that are precursors to pancreatic cancer

Bacteria from the digestive system seem to have the potential to cause damage to pancreatic cells, increasing the risk of malignant tumors.

24 Nov 2021

Can dexamethasone reduce prolonged COVID-19 symptoms?

A new study assesses hospitalized patients after recovering from COVID-19 by comparing the individuals before and after being treated with dexamethasone.

24 Nov 2021

Bat coronavirus ecology, evolution, and spillover

In a review published in Nature Reviews Microbiology, the authors collate information about the ecology and evolution of bat coronaviruses.

24 Nov 2021

Vaping linked to dysregulation of mitochondrial genes and immune response genes

Since they hit the market, e-cigarettes have been touted as a safe alternative to tobacco cigarettes for adult smokers.

24 Nov 2021

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

A new study evaluates the efficacy of SNX-5422 as a post-exposure prophylactic treatment.

23 Nov 2021

KHN’s ‘What the Health?’: The big Biden budget bill passes the House

President Joe Biden's "Build Back Better" social spending bill passed the House last week, but the legislation faces a new and different set of hurdles in the Senate, where it will need the support of every single Democrat, plus approval by the Senate parliamentarian.

23 Nov 2021

Oral News and Research

SARS-CoV-2 Delta saliva viral load 15 times that of the wild type

Systematic review: The involvement of bitter taste receptors in cancer

Risk of COVID-19 hospitalization among children with markers of uncontrolled asthma

New California law eases aid-in-dying process

Natural triterpenoids in licorice found to inhibit SARS-CoV-2

Conservative justices seem poised to overturn Roe’s abortion rights

Impact of SARS-CoV-2 on oral health

Teriflunomide tempers lesion growth in pediatric patients with multiple sclerosis

Omicron and other coronavirus variants: What you need to know

Study finds atazanavir inhibits main SARS-CoV-2 protease

Persistent opioid use among 12% of patients after cardiac implantable electronic device procedures

Prevalence of menstrual changes following vaccination against COVID-19

Combination of two targeted drugs shows "clinically meaningful" activity in some malignant brain tumors

Direct-acting antivirals for HCV-related hepatocellular carcinoma reduces the risk of tumor progression

Researchers analyze live bacteria from cystic lesions that are precursors to pancreatic cancer

Can dexamethasone reduce prolonged COVID-19 symptoms?

Bat coronavirus ecology, evolution, and spillover

Vaping linked to dysregulation of mitochondrial genes and immune response genes

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

KHN’s ‘What the Health?’: The big Biden budget bill passes the House

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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