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BioNano Genomics' IrysChip V2 named Top 10 Innovations of 2014

BioNano Genomics, the leader in genome mapping, announced today that The Scientist named the Company's IrysChip™ V2 one of the Top 10 Innovations of 2014.

1 Dec 2014

Phenotyping human diseases in mice: an interview with Professor Carola Vinuesa

One of the main obstacles to finding effective therapies for human diseases has been our limited understanding of disease pathogenesis: we lack detailed knowledge of the cellular and molecular mechanisms that lead to the development of disease.

30 Nov 2014

Grand Challenges Canada announces $1.2 million in grant for 11 new global health innovations

Grand Challenges Canada, funded by the Government of Canada, today announced $1.2 million in funding for 11 new global health innovations implemented in member states of La Francophonie.

29 Nov 2014

Health Canada warns Canadians against illegal health products

A vendor in Atlantic Canada (www.health-recovery-info.com) is selling Miracle Mineral Solution (MMS), an unauthorized drug product which Health Canada has previously warned may pose serious risks to health if ingested.

29 Nov 2014

CHP Canada commends launch of consultations on proposed consumer health products

Consumer Health Products Canada (CHP Canada) applauds federal Health Minister Rona Ambrose for beginning consultations on a proposed consumer health products framework.

29 Nov 2014

Lord Saatchi's Medical Innovation Bill may cause serious harm to patients

The Medical Innovation Bill tabled by Lord Saatchi and currently making its way through the UK’s House of Lords “strikes at the heart of evidence-based medicine” and risks “opening the door to the use of less proven, or unproven, approaches such as complementary or alternative medicine”, according to a new Editorial published in The Lancet Oncology.

29 Nov 2014

Researchers investigate FDA influence for improving pivotal drug studies

An examination of the potential interaction between pharmaceutical companies and the U.S. Food and Drug Administration (FDA) to discuss future studies finds that one-quarter of recent new drug approvals occurred without any meeting, and when such meetings occurred, pharmaceutical companies did not comply with one-quarter of the recommendations made by the FDA regarding study design or primary outcome, according to a study in the November 26 issue of JAMA.

28 Nov 2014

Study provides proof of concept for developing antibodies against human pathogens

Scientists investigating the potentially deadly hantavirus have used a novel approach to developing protective antibodies against it. Their work, published in today's online edition of Science Translational Medicine, provides proof of concept for producing antibodies against a broad range of human pathogens.

28 Nov 2014

Experimental drug works best when patients' immune cells surrounding tumors express PD-L1

A promising experimental immunotherapy drug works best in patients whose immune defenses initially rally to attack the cancer but then are stymied by a molecular brake that shuts down the response, according to a new study led by researchers at Dana-Farber Cancer Institute and the Yale University School of Medicine.

28 Nov 2014

UCL research opens up new way to treat neurological disorders

The way that tetanus neurotoxin enters nerve cells has been discovered by UCL scientists, who showed that this process can be blocked, offering a potential therapeutic intervention for tetanus. This newly-discovered pathway could be exploited to deliver therapies to the nervous system, opening up a whole new way to treat neurological disorders such as motor neuron disease and peripheral neuropathies.

28 Nov 2014

Behavioural, drug interventions aiming to prevent progression to diabetes equally effective for both sexes

Behavioural and drug interventions aiming to prevent people with prediabetes progressing to full blown type 2 diabetes are equally effective for both sexes at preventing progression and reducing weight, according to a new systematic review and meta-analysis.

28 Nov 2014

New guideline now available to help prevent, treat delirium in older patients

A new guideline is available to help health care providers prevent and treat one of the most common postoperative complications in older patients, delirium, which is an episode of sudden confusion.

27 Nov 2014

Researchers identify mechanism linked to brain damage

Researchers have discovered a mechanism linked to the brain damage often suffered by stroke victims--and are now searching for drugs to block it.

27 Nov 2014

Hovione submits first IND Application with FDA for minocycline gel

Hovione announced today it has filed its first Investigational New Drug (IND) Application with the U.S. Food and Drug Administration. This event represents a milestone in Hovione's strategy of developing improved drug delivery options for established drugs.

27 Nov 2014

Immune-suppressing protein may predict how patients respond to treatment

The presence of an immune-suppressing protein in non-cancerous immune cells may predict how patients with different types of cancer respond to treatment, a multi-center phase I study using an investigational immune therapy drug has found.

27 Nov 2014

Plymouth professor awarded grant to find effective treatment for patients with mantle cell lymphoma

Professor Simon Rule, Professor in Haematology at Plymouth University Peninsula Schools of Medicine and Dentistry and Consultant Haematologist at Plymouth Hospitals NHS Trust, has been awarded a significant grant by Cancer Research UK to carry out a research study into the treatment of older patients with mantle cell lymphoma.

27 Nov 2014

Leading medical experts across the UK call for radical scale up of liver disease treatment

Leading medical experts today [Thursday 27 November] warn that rising numbers of deaths from liver disease - already the UK's third commonest cause of premature death - will be unavoidable without radical improvements in treatment and detection services, and tougher government policies to control the excessive alcohol use and obesity responsible for much of the national burden of liver disease.

27 Nov 2014

HIV drugs could be harnessed to treat leading cause of blindness

An established class of drugs, traditionally used to control HIV/AIDS infections, could soon be harnessed to treat the leading cause of blindness and visual impairment in the UK, for which currently there exists no cure.

27 Nov 2014

Researchers investigate role of mitochondria in expansion, survival of cancer stem cells

Cancer stem cells are particularly difficult to eradicate and are at the heart of why it is so hard to more effectively treat cancer patients, as the post-treatment survival of cancer stem cells drives tumour recurrence, the systemic spread of cancer and, ultimately, treatment failure.

From The University of Manchester 27 Nov 2014

IQWiG comments on WHO Statement on Public Disclosure of Clinical Trial Results

The German Institute for Quality and Efficiency in Health Care (IQWiG) commented on the World Health Organization's (WHO) Statement on Public Disclosure of Clinical Trial Results.

27 Nov 2014

Drugs News and Research

BioNano Genomics' IrysChip V2 named Top 10 Innovations of 2014

Phenotyping human diseases in mice: an interview with Professor Carola Vinuesa

Grand Challenges Canada announces $1.2 million in grant for 11 new global health innovations

Health Canada warns Canadians against illegal health products

CHP Canada commends launch of consultations on proposed consumer health products

Lord Saatchi's Medical Innovation Bill may cause serious harm to patients

Researchers investigate FDA influence for improving pivotal drug studies

Study provides proof of concept for developing antibodies against human pathogens

Experimental drug works best when patients' immune cells surrounding tumors express PD-L1

UCL research opens up new way to treat neurological disorders

Behavioural, drug interventions aiming to prevent progression to diabetes equally effective for both sexes

New guideline now available to help prevent, treat delirium in older patients

Researchers identify mechanism linked to brain damage

Hovione submits first IND Application with FDA for minocycline gel

Immune-suppressing protein may predict how patients respond to treatment

Plymouth professor awarded grant to find effective treatment for patients with mantle cell lymphoma

Leading medical experts across the UK call for radical scale up of liver disease treatment

HIV drugs could be harnessed to treat leading cause of blindness

Researchers investigate role of mitochondria in expansion, survival of cancer stem cells

IQWiG comments on WHO Statement on Public Disclosure of Clinical Trial Results

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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