Genes News and Research

RSS

Restless legs syndrome common and troublesome in children and adolescents

Restless legs syndrome is a common problem in children 8 years of age and older in the United States and the United Kingdom, according to a new report from an international team of researchers.

24 Aug 2007

Breakthrough for Huntington's disease

A major breakthrough in the understanding and potential treatment of Huntington's disease has been made by scientists at the University of Leeds.

24 Aug 2007

Discovery of new gene family essential for embryonic development

The family controls the expression of genes crucial for stem cell maintenance and differentiation, and the results may contribute sig-nificantly to the understanding of the development of cancer.

24 Aug 2007

Potential new strategies for treating obsessive compulsive disorder

Using genetic engineering, researchers have created an obsessive-compulsive disorder (OCD) - like set of behaviors in mice and reversed them with antidepressants and genetic targeting of a key brain circuit.

24 Aug 2007

All eukaryotic kinases share 1 common set of substrates

Kinase mediated phosphorylation is generally recognised as the major regulator of virtually all metabolic activities in eukaryotic cells including proliferation, gene expression, motility, vesicular transport and programmed cell death.

24 Aug 2007

Migration of antibiotic resistance from animal feeding operations into groundwater

The routine use of antibiotics in swine production can have unintended consequences, with antibiotic resistance genes sometimes leaking from waste lagoons into groundwater.

22 Aug 2007

Genetics determine optimal drug dose of warfarin

Genetic testing can be used to help personalize the therapeutic dosage of warfarin, a commonly-used anticoagulant, according to research published in the September 1, 2007, issue of Blood , the journal of the American Society of Hematology.

22 Aug 2007

Traffic and childhood asthma

Children who carry variations in specific genes that metabolize vehicle emissions are more susceptible to developing asthma, particularly if they live near major roadways, a study led by researchers at the University of Southern California (USC) suggests.

22 Aug 2007

Exhaust fumes increase risk for asthma in genetically susceptible children

Exhaust fumes heighten the risk of asthma in children who are already genetically susceptible to respiratory disease, indicates research published ahead of print in the journal Thorax.

22 Aug 2007

New Cockayne syndrome discovery

Scientists of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have shown that the genetic defect that causes Cockayne Syndrome affects a key function of the cell – the transcription of genes coding for ribosomal RNA.

21 Aug 2007

Genetic testing can be used to help personalize the therapeutic dosage of warfarin

Genetic testing can be used to help personalize the therapeutic dosage of warfarin, a commonly-used anticoagulant, according to research published in the September 1, 2007, issue of Blood, the journal of the American Society of Hematology.

21 Aug 2007

Hypertension in African Americans - forthcoming study will look at how genes can contribute to hypertension

Exercise cannot reduce a sodium-retaining hormone in African Americans known to potentially cause hypertension, found Michael D. Brown, Ph.D., the senior author of a study in the September issue of Experimental Physiology. Brown is an associate professor of kinesiology at Temple University's College of Health Professions.

17 Aug 2007

Proteins involved in fragile X syndrome identified

The interplay of two proteins that bind to messenger RNA, a molecule that mediates translation of the information encoded in genes into proteins, triggers the appearance of fragile X-associated tremor/ataxia syndrome (FTAX), a late-life disorder associated with the gene that causes fragile X syndrome in children, said researchers from Baylor College of Medicine in Houston and Emory University School of Medicine in a report that appears today in the journal Neuron.

17 Aug 2007

Reactivating a critical gene lost in kidney cancer reduces tumor growth

Researchers at Mayo Clinic Jacksonville, have found that a key gene is often silenced in clear cell renal cell carcinoma, the most common type of kidney cancer, and when they restored that gene in human kidney cancer cells in culture and animal experiments, tumors stopped growing and many disappeared.

17 Aug 2007

FDA approves updated labeling for Warfarin (Coumadin)

The U.S. Food and Drug Administration has announced the approval of updated labeling for the widely used blood-thinning drug, Coumadin, to explain that people's genetic makeup may influence how they respond to the drug.

17 Aug 2007

Effectiveness of mouse breeds that mimic Alzheimer's disease symptoms questioned

Scientists have shown that recently developed mouse breeds that mimic the symptoms of Alzheimer's disease (AD) may not be as effective as previously assumed.

17 Aug 2007

Mitochondrial DNA variants are linked to risk factors for type 2 diabetes

Researchers report for the first time that genetic variants in mitochondria,energy-producing structures harboring DNA that are inherited only from the mother,are directly linked to metabolic markers for type 2 diabetes.

13 Aug 2007

Discovery of new mechanism of resistance to endocrine or anti-hormonal therapies

When a woman receives a breast cancer diagnosis her entire life may change in the blink of an eye.

13 Aug 2007

Impaired energy production in heart muscle may underlie heart failure in some hypertensive patients

Many people with long-standing high blood pressure develop heart failure. But some don't. Daniel P. Kelly, M.D., and colleagues at Washington University School of Medicine in St. Louis and other institutions are trying to figure out what could explain that difference.

13 Aug 2007

Gene use sets humans and chimps apart

The striking differences between humans and chimps aren't so much in the genes we have, which are 99 percent the same, but in the way those genes are used, according to new research from a Duke University team.

13 Aug 2007