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Rainforest vine compound makes pancreatic cancer cells susceptible to nutrient starvation

Pancreatic cancer cells are known for their ability to thrive under extreme conditions of low nutrients and oxygen, a trait known in the cancer field as "austerity." The cells' remarkable resistance to starvation is one reason why pancreatic cancer is so deadly.

14 Nov 2018

Microgel powder reduces infection and promotes healing

While making smart glue, a team of engineers discovered a handy byproduct: hydrogen peroxide. In microgel form, it reduces bacteria and virus ability to infect by at least 99 percent.

14 Nov 2018

Human Cell Atlas study of early pregnancy shows how mother's immune system is modified

The first Human Cell Atlas study of early pregnancy in humans has shown how the function of the maternal immune system is affected by cells from the developing placenta.

14 Nov 2018

Researchers evaluate efficacy of salivary biomarkers for early detection of oral cancer

Over 90% of malign tumors in the head and neck are originated from carcinomas of squamous cells that appear in superficial areas of the oral cavity. Their detection with salivary biomarkers can contribute to their early treatment, before they transform into tumors.

14 Nov 2018

Research explores how exercise may help fight drug addiction

The siren call of addictive drugs can be hard to resist, and returning to the environment where drugs were previously taken can make resistance that much harder.

14 Nov 2018

Two genomic tests help identify most effective treatment for breast cancer patients

New results from a long-running trial to identify which new drugs or combinations of drugs are most effective in which types of breast cancer, show that two genomic tests are bringing the era of truly personalized medicine ever nearer.

14 Nov 2018

Researchers develop innovative treatment to repair damaged brain tissues

Researchers from Universidad Politécnica de Madrid have has achieved the functional recovery from a stroke after implanting silk fibroin hydrogels-encapsulated stem cells in stroke mice.

14 Nov 2018

Study sheds light on mechanisms that prevent autoimmune attack

Understanding the mechanisms that prevent our immune system damaging healthy cells, whilst fighting infection and cancer, could lead to the development of novel immune-regulating treatments.

14 Nov 2018

NIH researchers shed light on causes of HBV-associated acute liver failure

National Institutes of Health scientists and their collaborators found that hepatitis B virus-associated acute liver failure--a rare condition that can turn fatal within days without liver transplantation--results from an uncommon encounter between a highly mutated HBV variant and an unusual immune response in the patient's liver that is mainly sustained by antibody-producing B cells.

14 Nov 2018

Speed and error rate of DNA synthesis influenced by DNA structure

The speed and error rate of DNA synthesis is influenced by the three-dimensional structure of the DNA. Using "third-generation" genome-wide DNA sequencing data, a team of researchers from Penn State and the Czech Academy of Sciences showed that sequences with the potential to form unusual DNA conformations, which are frequently associated with cancer and neurological diseases, can in fact slow down or speed up the DNA synthesis process and cause more or fewer sequencing errors.

14 Nov 2018

Study defines biomarker in response to treatment of castration-resistant prostate cancer

The most aggressive type of prostate cancer, castration-resistant prostate cancer, can be treated with two different therapies: taxanes or hormone treatment. Until this day there are no comparative studies between the two and the decision on which treatment to use is done empirically and based on the patient's preferences.

14 Nov 2018

New technology based on moths and magnets could help treat genetic diseases

A new technology that relies on a moth-infecting virus and nanomagnets could be used to edit defective genes that give rise to diseases like sickle cell, muscular dystrophy and cystic fibrosis.

14 Nov 2018

Determining how hearts develop to better understand congenital heart defects

To understand cardiovascular failures, the leading cause of birth defect-related deaths in infants, UH professor of biomedical engineering Kirill Larin is teaming up with Baylor College of Medicine professor of cellular and molecular physiology Irina Larina on a chicken and egg hunt.

14 Nov 2018

New anti-HER2 drug shows promising anti-tumor activity in gullet, stomach and bowel cancers

An antibody that binds simultaneously to two distinct regions of the HER2 receptor to block the growth of cancer cells has shown promising signs of anti-tumor activity in a number of cancers including those of the gullet (esophagus), stomach and bowel.

14 Nov 2018

B Cell News and Research

Rainforest vine compound makes pancreatic cancer cells susceptible to nutrient starvation

Microgel powder reduces infection and promotes healing

Human Cell Atlas study of early pregnancy shows how mother's immune system is modified

Researchers evaluate efficacy of salivary biomarkers for early detection of oral cancer

Research explores how exercise may help fight drug addiction

Two genomic tests help identify most effective treatment for breast cancer patients

Researchers develop innovative treatment to repair damaged brain tissues

Study sheds light on mechanisms that prevent autoimmune attack

NIH researchers shed light on causes of HBV-associated acute liver failure

Speed and error rate of DNA synthesis influenced by DNA structure

Study defines biomarker in response to treatment of castration-resistant prostate cancer

New technology based on moths and magnets could help treat genetic diseases

Determining how hearts develop to better understand congenital heart defects

New anti-HER2 drug shows promising anti-tumor activity in gullet, stomach and bowel cancers

Nitric oxide-releasing technology shows potential to reduce healing time of diabetic foot ulcers

Study identifies potential therapeutic strategy for patients with clear cell renal cancer

Researchers unravel mystery of NPM1 protein in acute myeloid leukemia

Breakthrough research could lead to a new wave of cancer-fighting antibodies

Study shows new emerging role of osteopontin in HCV-related hepatocellular carcinoma

Neural networks could replace marker genes in RNA sequencing

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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