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Bacterial protein flagellin can prevent and cure rotavirus infection

Activation of the innate immune system with the bacterial protein flagellin could prevent and cure rotavirus infection, which is among the most common causes of severe diarrhea, says a Georgia State University research team that described the method as a novel means to prevent and treat viral infection.

14 Nov 2014

Study shows how anesthesia affects cells in central nervous system

Anesthesia, long considered a blessing to patients and surgeons, has been a mystery for much of its 160-plus-year history in the operating room.

14 Nov 2014

New study shows that brain’s ability to manage stress depends on brain protein

The brain's ability to effectively deal with stress or to lack that ability and be more susceptible to depression, depends on a single protein type in each person's brain, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published November 12 in the journal Nature.

14 Nov 2014

Genetic testing, risk factor assessment could improve prevention strategies for breast cancer

Scientists used mathematical models to show that analysing genetic data, alongside a range of other risk factors, could substantially improve the ability to flag up women at highest risk of developing breast cancer.

14 Nov 2014

Isis Pharmaceuticals, AstraZeneca partner to develop new delivery methods for antisense oligonucleotides

AstraZeneca and Isis Pharmaceuticals Inc. today announced a strategic alliance to discover and develop novel delivery methods for antisense oligonucleotides.

14 Nov 2014

Research shows mustard and garlic receptor is linked to cold-induced pain

Some people experience cold not only as feeling cold, but actually as a painful sensation. This applies even to fairly mild temperatures - anything below 20°C.

14 Nov 2014

Rare gene mutation linked to lower cholesterol levels, reduced risk of heart attack

Rare mutations that shut down a single gene are linked to lower cholesterol levels and a 50 percent reduction in the risk of heart attack, according to new research from Washington University School of Medicine in St. Louis, the Broad Institute at Massachusetts Institute of Technology and Harvard, and other institutions.

14 Nov 2014

Multi-institutional study establishes new criteria for Alzheimer's-related memory disorder

A multi-institutional study has defined and established criteria for a new neurological disease closely resembling Alzheimer's disease called primary age-related tauopathy (PART).

14 Nov 2014

Concordia Healthcare reports record revenues of 147% in third quarter 2014

Concordia Healthcare Corp. ("Concordia" or the "Company"), a diverse healthcare company focused on legacy pharmaceutical products, orphan drugs, and medical devices for the diabetic population, today announced its financial and operational results for the three and nine months ended September 30, 2014.

14 Nov 2014

Representatives from 40 countries meet to discuss plan for antimicrobial resistance

Every year, 25,000 people die as a result of antimicrobial resistance in Europe. A global action plan against one of the greatest health threats of our time is the aim of a conference being held in Oslo on 13th-14th November.

14 Nov 2014

Montefiore Medical Center receives $3.5M grant to advance treatment for hepatitis C

Montefiore Medical Center received a $3.5 million grant as part of the $10 million Health Care Innovation Award from the Center for Medicare & Medicaid Services to identify, diagnose and treat people with hepatitis C (HCV).

13 Nov 2014

University of Leeds researchers make new synthetic anti-cancer molecule

Researchers at the University of Leeds have made a new synthetic anti-cancer molecule that targets two key mechanisms in the spread of malignant tumours through the body.

13 Nov 2014

Researchers find key mechanism that could lead to new effective treatments for leukemias

Researchers have identified two proteins that appear crucial to the development -- and patient relapse -- of acute myeloid leukemia. They have also shown they can block the development of leukemia by targeting those proteins.

13 Nov 2014

U of G research may lead to novel treatment approaches for late-stage ovarian cancer

In a potential breakthrough against ovarian cancer, University of Guelph researchers have discovered how to both shrink tumours and improve drug delivery, allowing for lower doses of chemotherapy and reducing side effects.

13 Nov 2014

Study defines, establishes criteria for primary age-related tauopathy

A multi-institutional study has defined and established criteria for a new neurological disease closely resembling Alzheimer's disease called primary age-related tauopathy (PART). Patients with PART develop cognitive impairment that can be indistinguishable from Alzheimer's disease, but they lack amyloid plaques. Awareness of this neurological disease will help doctors diagnose and develop more effective treatments for patients with different types of memory impairment.

13 Nov 2014

Toxicity profiles for everolimus, temsirolimus differ in advanced RCC

Non-infectious pneumonitis and stomatitis occur more frequently in patients with advanced renal cell carcinoma treated with everolimus than temsirolimus, whereas temsirolimus is associated with a higher incidence of fatigue, rash and asthenia, a retrospective study reports.

13 Nov 2014

Drugs News and Research

Bacterial protein flagellin can prevent and cure rotavirus infection

Study shows how anesthesia affects cells in central nervous system

New study shows that brain’s ability to manage stress depends on brain protein

Genetic testing, risk factor assessment could improve prevention strategies for breast cancer

Isis Pharmaceuticals, AstraZeneca partner to develop new delivery methods for antisense oligonucleotides

Research shows mustard and garlic receptor is linked to cold-induced pain

Rare gene mutation linked to lower cholesterol levels, reduced risk of heart attack

Multi-institutional study establishes new criteria for Alzheimer's-related memory disorder

Concordia Healthcare reports record revenues of 147% in third quarter 2014

Representatives from 40 countries meet to discuss plan for antimicrobial resistance

Montefiore Medical Center receives $3.5M grant to advance treatment for hepatitis C

University of Leeds researchers make new synthetic anti-cancer molecule

Researchers find key mechanism that could lead to new effective treatments for leukemias

U of G research may lead to novel treatment approaches for late-stage ovarian cancer

Study defines, establishes criteria for primary age-related tauopathy

Toxicity profiles for everolimus, temsirolimus differ in advanced RCC

Bevacizumab–erlotinib combined efficacy may depend on VEGF level

Experimental Ebola treatments to be trialled in West Africa next month

Scientists use Rapid Heme Panel test to identify right treatment for leukemia, other blood cancers

Study identifies genetic alterations that contribute to growth and recurrence of Ewing sarcoma

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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