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Study reveals that miR-7 suppresses gastric cancer by inhibiting key signaling pathway

A study in The Journal of Cell Biology reveals that the microRNA miR-7 suppresses gastric (stomach) cancer by inhibiting a key signaling pathway, and that this protective mechanism is compromised by the cancer-causing bacterium H. pylori. Finding drugs capable of inducing miR-7 could therefore prove to be an effective treatment against the progression of gastric cancer.

11 Aug 2015

UNC researchers show how a genetic mutation disables molecular switch and causes autism

Last December, researchers identified more than 1,000 gene mutations in individuals with autism, but how these mutations increased risk for autism was unclear. Now, UNC School of Medicine researchers are the first to show how one of these mutations disables a molecular switch in one of these genes and causes autism.

7 Aug 2015

Scientists develop biosensor to measure abnormal activity of cell 'fuel' carrier

To be able to function, cell mitochondria import "fuel" using a carrier, the Mitochondrial Pyruvate Carrier (MPC). In order to determine whether the MPC is still functional in malignant cells, the team of Professor Jean-Claude Martinou, at the University of Geneva, Switzerland, has just developed a biosensor to measure its live activity.

7 Aug 2015

Non-surgical approach to treating 'double chins'

UT Southwestern Medical Center plastic surgeons have a non-surgical approach to treating "double chins" − the moderate-to-severe fat below the chin using an FDA-approved drug that when injected into tissue destroys fat cells.

5 Aug 2015

MD Anderson scientists reveal role of metabolic enzyme fumarase in DNA repair

DNA double-strand breaks (DSBs) are the worst possible form of genetic malfunction that can cause cancer and resistance to therapy. New information published this week reveals more about why this occurs and how these breaks can be repaired.

4 Aug 2015

New research shows promising progress in use of anti-inflammatory cytokine for T1D treatment

New research from Uppsala University shows promising progress in the use of anti-inflammatory cytokine for treatment of type 1 diabetes. The study, published in the open access journal Scientific Reports (Nature Publishing Group), reveals that administration of interleukin-35 (a protein made by immune cells) to mice with type 1 diabetes, reverses or cures the disease by maintaining a normal blood glucose level and the immune tolerance.

30 Jul 2015

Protecting gastrointestinal system during radiation or chemotherapy allows patients to tolerate cancer treatments

The stem cells in our gut divide so fast that they create a completely new population of epithelial cells every week. But this quick division is also why radiation and chemotherapy wreak havoc on the gastrointestinal systems of cancer patients - such therapies target rapidly dividing cells.

30 Jul 2015

Understanding the workings of error correction mechanism in cell division

Cell biologists led by Thomas Maresca at the University of Massachusetts Amherst, with collaborators elsewhere, report an advance in understanding the workings of an error correction mechanism that helps cells detect and correct mistakes in cell division early enough to prevent chromosome mis-segregation and aneuploidy, that is, having too many or too few chromosomes.

30 Jul 2015

Recipients of GSA poster awards announced at 20th International C. elegans Meeting

The Genetics Society of America and the C. elegans research community are pleased to announce the recipients of the GSA poster awards at the 20th International C. elegans Meeting, which took place at the University of California, Los Angeles, June 24-28, 2015.

28 Jul 2015

Researchers discover first fully synthetic substrate with potential to grow billions of stem cells

If you experience a major heart attack the damage could cost you around five billion heart cells. Future stem cell treatments will require this number and more to ensure those cells are replaced and improve your chances of survival.

25 Jul 2015

Endocrine Society selects 18 endocrinologists as winners of 2016 Laureate Awards

The Endocrine Society today announced it has chosen 18 accomplished endocrinologists as winners of the organization's prestigious 2016 Laureate Awards.

24 Jul 2015

Study identifies new culprit in Alzheimer's disease development

A recent study conducted at Nathan S. Kline Institute for Psychiatric Research and NYU Langone Medical Center implicates a new culprit in Alzheimer's disease development. The research reveals that ßCTF -- the precursor of the amyloid beta (Aß) peptide -- acts at the earliest stage of Alzheimer's to initiate a range of abnormalities leading to the loss of groups of neurons critical for memory formation.

22 Jul 2015

UT Southwestern researchers find potential therapy to treat diabetes, nonalcoholic fatty liver disease

Reducing high concentrations of a fatty molecule that is commonly found in people with diabetes and nonalcoholic fatty liver disease rapidly improves insulin sensitivity, UT Southwestern Medical Center diabetes researchers have found.

17 Jul 2015

Novel cancer drug candidate developed in Singapore advances into clinical trials

A made-in-Singapore cancer drug has advanced into clinical trials, charting a milestone in Singapore's biomedical sciences initiative that will go towards improving the lives of cancer patients in Singapore, and worldwide.

17 Jul 2015

UAB researchers find therapeutic target for treatment of acute spinal cord injuries

UAB researchers have identified a therapeutic target for the treatment of acute spinal cord injuries. According to this research, conducted on mice, the administration of a drug that prevents loss of myelin - the insulating sheath around nerve fibres that allows signals to be transmitted - increases the mobility of the mice after an injury.

15 Jul 2015

Transplanted MSCs slow progression of lupus nephritis by suppressing Tfh cells in SLE animal model

Systemic lupus erythematosus (SLE) is an autoimmune disease that produces autoantibodies and subsequent immune reactions that can lead to a variety of symptoms, including inflammation of the kidneys, or nephritis. When researchers transplanted mesenchymal stem cells (MSCs) derived from human bone marrow into mice modeled with SLE, they found that inflammation was reduced and nephritis "attenuated."

15 Jul 2015

Salk professor receives Allen Distinguished Investigator award to uncover biology of Alzheimer's disease

The Salk Institute today announced that Rusty Gage, Salk professor in the Laboratory of Genetics, has been selected as one of five recipients of the Paul G. Allen Family Foundation's Allen Distinguished Investigator (ADI) program and will be awarded $1.5 million to conduct his research. These researchers have projects aimed at uncovering the elusive biological foundations of Alzheimer's disease.

15 Jul 2015

Correlated Light & Electron Microscopy at the Universities of Delft and Groningen

DELMIC develops and manufactures products which are focused on high performance, user friendly, integrated microscopy solutions. Users of Delmic's SECOM solution for Correlated Light & Electron Microscopy (CLEM) have recently published a review in Nature Methods that illustrates the power of CLEM in the world of biology.

From Delmic B.V. 14 Jul 2015

Paul G. Allen Family Foundation announces ADI grants for Alzheimer's disease research

The Paul G. Allen Family Foundation announced today the award of Allen Distinguished Investigator (ADI) grants to five teams of researchers with projects that will open new and innovative avenues of research in Alzheimer's disease by uncovering its elusive biological roots.

14 Jul 2015

Duke University researchers devise new method for making potential nanoscale cancer treatment

In a move akin to adding chemical weapons to a firebomb, researchers at Duke University have devised a method for making a promising nanoscale cancer treatment even more deadly to tumors.

14 Jul 2015

Cell Biology News and Research

Study reveals that miR-7 suppresses gastric cancer by inhibiting key signaling pathway

UNC researchers show how a genetic mutation disables molecular switch and causes autism

Scientists develop biosensor to measure abnormal activity of cell 'fuel' carrier

Non-surgical approach to treating 'double chins'

MD Anderson scientists reveal role of metabolic enzyme fumarase in DNA repair

New research shows promising progress in use of anti-inflammatory cytokine for T1D treatment

Protecting gastrointestinal system during radiation or chemotherapy allows patients to tolerate cancer treatments

Understanding the workings of error correction mechanism in cell division

Recipients of GSA poster awards announced at 20th International C. elegans Meeting

Researchers discover first fully synthetic substrate with potential to grow billions of stem cells

Endocrine Society selects 18 endocrinologists as winners of 2016 Laureate Awards

Study identifies new culprit in Alzheimer's disease development

UT Southwestern researchers find potential therapy to treat diabetes, nonalcoholic fatty liver disease

Novel cancer drug candidate developed in Singapore advances into clinical trials

UAB researchers find therapeutic target for treatment of acute spinal cord injuries

Transplanted MSCs slow progression of lupus nephritis by suppressing Tfh cells in SLE animal model

Salk professor receives Allen Distinguished Investigator award to uncover biology of Alzheimer's disease

Correlated Light & Electron Microscopy at the Universities of Delft and Groningen

Paul G. Allen Family Foundation announces ADI grants for Alzheimer's disease research

Duke University researchers devise new method for making potential nanoscale cancer treatment

Improve fermentation and cell culture performance with real-time gas analysis eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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