Malignant News and Research

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Systemic stem cell therapy reduces malignant mesothelioma growth

Systemic delivery of stem cells expressing an apoptosis-inducing protein can successfully incorporate into malignant pleural mesothelioma cells and subsequently induce their death, according to preclinical study findings.

19 Mar 2014

Archaeologists find oldest complete example of metastatic cancer in 3,000 year-old skeleton

Archaeologists have found the oldest complete example in the world of a human with metastatic cancer in a 3,000 year-old skeleton.

19 Mar 2014

Findings open way to identification of new cancer drugs to fight acute myeloid leukemia

The Institute for Research in Immunology and Cancer (IRIC) at the Université de Montréal (UdeM), in collaboration with the Maisonneuve-Rosemont Hospital's Quebec Leukemia Cell Bank, recently achieved a significant breakthrough thanks to the laboratory growth of leukemic stem cells, which will speed up the development of new cancer drugs.

18 Mar 2014

Proteomics identifies possible RCC biomarkers

Proteomic analysis has identified significant differences between the proteins expressed in renal cell carcinoma samples and in healthy renal tissue, UK researchers report.

17 Mar 2014

Longer looks: The 'making of Obamacare;' unlocking an autistic son's secrets; antibiotics and the obesity epidemic

If you walk into a farm-supply store today, you're likely to find a bag of antibiotic powder that claims to boost the growth of poultry and livestock. That's because decades of agricultural research has shown that antibiotics seem to flip a switch in young animals' bodies, helping them pack on pounds. Manufacturers brag about the miraculous effects of feeding antibiotics to chicks and nursing calves. Dusty agricultural journals attest to the ways in which the drugs can act like a kind of superfood to produce cheap meat. But what if that meat is us? (Pagan Kennedy, 3/8).

14 Mar 2014

Patients with congenital disorders are urged to register with CMDIR to advance clinical trials

If you are affected by Malignant Hyperthermia, Congenital Muscular Dystrophies or Congenital Myopathy Subtypes, the Malignant Hyperthermia Association of the United States and the Cure Congenital Muscle Disease organization are asking for your help to enable research and clinical trials by registering with the Congenital Muscle Disease International Registry (CMDIR).

13 Mar 2014

Scientist receives AGA-GCF Research Scholar Award for research in gastric, esophageal cancer

The American Gastroenterological Association (AGA) Research Foundation and the Gastric Cancer Foundation (GCF) are pleased to announce that the first AGA-Gastric Cancer Foundation Research Scholar Award in Gastric and Esophageal Cancer will support Mohamed El-Zaatari, PhD, from University of Michigan, as he conducts research into the role of myeloid cells in the transition from chronic inflammation to gastric pre-neoplasia.

12 Mar 2014

Skin cancer may increase risk of other cancers later in life

Australian author on the paper, Professor Rodney Sinclair, Professor of Medicine at the University of Melbourne and Director of Dermatology at Epworth HealthCare said that the risk decreased significantly with increasing age, but it remains higher compared with individuals who have never had NMSC.

10 Mar 2014

Researchers unravel function of proteins involved in cell metabolism

UCPs or uncoupling proteins are present in mitochondria, the powerhouse of each cell in the body. The functions of most of the five known UCPs remain mysterious (UCP2-UCP5), whereby only the distinct function for UCP1 has thus far been discovered.

5 Mar 2014

Microgravity may suppress tumors, study reveals

In space, things don't always behave the way we expect them to. In the case of cancer, researchers have found that this is a good thing: some tumors seem to be much less aggressive in the microgravity environment of space compared to their behavior on Earth. This observation, reported in research published in February by the FASEB Journal, could help scientists understand the mechanism involved and develop drugs targeting tumors that don't respond to current treatments. This work is the latest in a large body of evidence on how space exploration benefits those of us on Earth.

4 Mar 2014

Levels of bisphenol A in men's urine could be marker of prostate cancer

Findings by Cincinnati Cancer Center researchers show that levels of bisphenol A (BPA) in men's urine could be a marker of prostate cancer and that low levels of BPA exposure can cause cellular changes in both non-malignant and malignant prostate cells.

4 Mar 2014

Research: Microbes living in gut help drive development of intestinal tumors

It is not only genetics that predispose to bowel cancer; microbes living in the gut help drive the development of intestinal tumors, according to new research in mice published in the March issue of The Journal of Experimental Medicine.

4 Mar 2014

Five women scientists to receive ‘L’Oréal-UNESCO For Women in Science Awards'

On March 19th the L'Oréal Foundation and UNESCO will present the L'Oréal-UNESCO For Women in Science awards to five outstanding women scientists.

3 Mar 2014

Sunburn causes melanoma through direct and indirect processes

Melanoma is particularly dangerous because it can form metastases in vital organs such as the lungs, liver or brain. UV radiation is considered to be the most significant triggering factor.

3 Mar 2014

Scientists unveil role of microRNAs in regulating neuroblastoma, pointing to new therapeutic possibilities

Neuroblastoma is one of the most common and lethal types of childhood cancers. In a paper published online today in OncoTarget, a researcher at the University of Texas Health Science Center at San Antonio unveils the important role of microRNAs in regulating neuroblastoma development, pointing to new therapeutic possibilities.

3 Mar 2014

Randomized trial of bevacizumab for glioblastoma shows disappointing results

"The results of this study are counter to most expectations," said Dr. Brachman, Director of Radiation Oncology at Barrow and St. Joseph's. "Bevacizumab had been shown in earlier studies to be an effective drug in the treatment of patients with recurrent disease. But, on newly diagnosed patients, it did not, in fact, prolong survival."

3 Mar 2014

Plasma microRNA test boosts lung cancer screening

The ability to screen for lung cancer is improved by the development of a plasma 24-microRNA signature classifier, research suggests.

28 Feb 2014

Chemo and radiation can kill more cancer cells and spare healthy ones, suggests Rutgers research

What if there were a way to make chemotherapy and radiation more effective as cancer treatments than they are today, while also getting rid of debilitating side effects that patients dread? A new study led by Alexey Ryazanov, a professor of pharmacology at Rutgers Robert Wood Johnson Medical School and member of the Rutgers Cancer Institute of New Jersey, suggests the day that happens could be getting closer.

27 Feb 2014

Study identifies promising target for new drugs to treat lethal form of brain cancer

A molecule in cells that shuts down the expression of genes might be a promising target for new drugs designed to treat the most frequent and lethal form of brain cancer, according to a new study by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

27 Feb 2014

UH scientists working to develop next generation of prostate cancer therapies

A University of Houston scientist and his team are working to develop the next generation of prostate cancer therapies, which are targeted at metabolism.

27 Feb 2014

Malignant News and Research

Systemic stem cell therapy reduces malignant mesothelioma growth

Archaeologists find oldest complete example of metastatic cancer in 3,000 year-old skeleton

Findings open way to identification of new cancer drugs to fight acute myeloid leukemia

Proteomics identifies possible RCC biomarkers

Longer looks: The 'making of Obamacare;' unlocking an autistic son's secrets; antibiotics and the obesity epidemic

Patients with congenital disorders are urged to register with CMDIR to advance clinical trials

Scientist receives AGA-GCF Research Scholar Award for research in gastric, esophageal cancer

Skin cancer may increase risk of other cancers later in life

Researchers unravel function of proteins involved in cell metabolism

Microgravity may suppress tumors, study reveals

Levels of bisphenol A in men's urine could be marker of prostate cancer

Research: Microbes living in gut help drive development of intestinal tumors

Five women scientists to receive ‘L’Oréal-UNESCO For Women in Science Awards'

Sunburn causes melanoma through direct and indirect processes

Scientists unveil role of microRNAs in regulating neuroblastoma, pointing to new therapeutic possibilities

Randomized trial of bevacizumab for glioblastoma shows disappointing results

Plasma microRNA test boosts lung cancer screening

Chemo and radiation can kill more cancer cells and spare healthy ones, suggests Rutgers research

Study identifies promising target for new drugs to treat lethal form of brain cancer

UH scientists working to develop next generation of prostate cancer therapies

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