OCT News and Research

RSS

New method to study the nuclear pore complex directly inside cells

Context matters. It's true for many facets of life, including the tiny molecular machines that perform vital functions inside our cells.

18 Oct 2021

Researchers discover a new paradigm for how biological switches are regulated

Quantitative Biosciences Institute (QBI) researchers at UC San Francisco have discovered a new paradigm for how fundamental biological switches, proteins that can be turned on and off to control processes like cell differentiation, cell growth, and transport within a cell, are regulated at the molecular level, specifically by molecules binding at newly discovered sites far away from the main binding site, and the broader impacts these changes have on a cellular level.

18 Oct 2021

People with obesity overrepresented among COVID-19 patients receiving intensive care

People with obesity were overrepresented among adults in Sweden receiving intensive care for COVID-19 during the first wave of the pandemic. Just over 39 percent had obesity, compared with some 16 percent in the population.

18 Oct 2021

Machine learning can yield "proxy measures" for brain-related health issues

A study published today by an interdisciplinary collaboration, directed by Denis Engemann from Inria, demonstrates that machine learning from large population cohorts can yield "proxy measures" for brain-related health issues without the need for a specialist's assessment.

18 Oct 2021

Research reveals how daily circadian rhythms help to change heart function

A new study has shown how circadian rhythms in heart cells help to change heart function over the course of the day and may explain why shift workers are more vulnerable to heart problems.

18 Oct 2021

Study finds connection between austerity measures and increased mortality in England

Central government austerity measures since 2010 are linked to tens of thousands more deaths than expected, finds research published in the online journal BMJ Open on the joint impact of social care, public health, and healthcare spends on death rates before and after 2010.

18 Oct 2021

Study explores the likelihood of inappropriate decisions by physicians during delivery

Clinical decisions made in the delivery setting as to whether to employ vaginal delivery or cesarean section are often made under high pressure, and with great uncertainty, and have serious consequences for mother and baby.

18 Oct 2021

Pandemic-related grief associated with lower levels of mother-infant bonding

The emotional connection between a mother and her newborn baby can lay the foundation for the child's development and the family's outcomes.

15 Oct 2021

Children with cerebral palsy benefit most from higher doses of CIMT therapy

Children with cerebral palsy can gain greater use of an impaired arm and hand with larger doses of Constraint-Induced Movement Therapy (CIMT) – without increasing stress for parents, according to a new study by researchers at Virginia Tech's Fralin Biomedical Research Institute at VTC, UVA Children's, The Ohio State University, and Nationwide Children's Hospital.

15 Oct 2021

AI-based technology rapidly identifies genetic causes of rare disorders with high accuracy

An artificial intelligence (AI)-based technology rapidly diagnoses rare disorders in critically ill children with high accuracy, according to a report by scientists from University of Utah Health and Fabric Genomics, collaborators on a study led by Rady Children's Hospital in San Diego.

15 Oct 2021

Novel method for rapid incidence estimation from SARS-CoV-2 genomes

Daily counts of new COVID-19 cases remain a basis for evaluating the state of the pandemic and are vital for making informed decisions on public interventions.

15 Oct 2021

AI algorithm accurately detects disease-causing variants in infants with rare diseases

Fabric Genomics and Rady Children's Institute for Genomic Medicine today announced the publication of a retrospective study in Genome Medicine showing that across six leading genomic centers and hospitals, researchers were able to detect more than 90% of disease-causing variants in infants with rare diseases using the Fabric GEM AI algorithm and whole-genome and whole-exome data from previously diagnosed newborns and rare disease patients at Rady Children's Hospital - San Diego and other clinical sites.

15 Oct 2021

Metabolic restoration as a therapeutic approach to promote natural immune protection against HIV

The human immunodeficiency virus (HIV-1) particularly attacks CD4 lymphocytes, a type of white blood cell considered to be the conductor of the immune system.

15 Oct 2021

New study shows how COVID-19 response has impacted the U.S. public health system

The cruel impact of COVID-19, the virus that emerged in late 2019 and has claimed 5 million lives to date, is chronicled in daily headlines. It has robbed us of loved ones, jobs, plans and so much more.

15 Oct 2021

New risk measure can better predict pandemic spread than other models

COVID-19 is not the flu. The disease caused by the novel SARS-CoV-2 virus is more transmissible, and deadlier, than most influenza epidemics we've encountered in our lifetimes, and scientists and physicians are still learning new things about the disease and its long-term effects.

15 Oct 2021

Mapping proteo-genomic connections between different human diseases

Hundreds of connections between different human diseases have been uncovered through their shared origin in our genome by an international research team led by scientists from the Medical Research Council Epidemiology Unit at the University of Cambridge, challenging the categorization of diseases by organ, symptoms, or clinical specialty.

15 Oct 2021

OCT News and Research

New method to study the nuclear pore complex directly inside cells

Researchers discover a new paradigm for how biological switches are regulated

People with obesity overrepresented among COVID-19 patients receiving intensive care

Machine learning can yield "proxy measures" for brain-related health issues

Research reveals how daily circadian rhythms help to change heart function

Study finds connection between austerity measures and increased mortality in England

Study explores the likelihood of inappropriate decisions by physicians during delivery

Pandemic-related grief associated with lower levels of mother-infant bonding

Children with cerebral palsy benefit most from higher doses of CIMT therapy

AI-based technology rapidly identifies genetic causes of rare disorders with high accuracy

Novel method for rapid incidence estimation from SARS-CoV-2 genomes

AI algorithm accurately detects disease-causing variants in infants with rare diseases

Metabolic restoration as a therapeutic approach to promote natural immune protection against HIV

New study shows how COVID-19 response has impacted the U.S. public health system

New risk measure can better predict pandemic spread than other models

Mapping proteo-genomic connections between different human diseases

Study finds high and increasing consumption of ultra-processed foods among Americans

Zinc oxide in sunscreens destroys UVA protection during sun exposure

Researchers explore how opioids may have become so widely abused

New atlas of small cell lung cancer reveals rare population of stem-like cells with metastatic properties

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

Latest News