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Treating pre-cancerous stem cells at early stage could be key to preventing bowel cancer

Treating pre-cancerous stem cells at an early stage could be key to preventing bowel cancer in people born with a very high risk of the disease, according to a study in mice presented at the 2018 NCRI Cancer Conference.

7 Nov 2018

Study identifies novel missense mutation affecting YARS causes multisystem disease

Researchers have identified a novel missense mutation in tyrosyl-tRNA synthetase (YARS c.499C>A, p.Pro167Thr) that causes a severe recessive disorder in affected individuals.

7 Nov 2018

WPI professor explores how lipids in our bodies and cell membranes affect aging, long-term health

A professor at Worcester Polytechnic Institute is exploring aging on the molecular level, examining how the lipids found in our bodies, particularly those in our cell membranes, change as we age, and how those changes may affect bone and muscle strength, brain health, and our propensity for age-related diseases, including Alzheimer's disease.

7 Nov 2018

Scientists discover new details about UHRF1 protein

Epigenetic changes often play an important role in cancer, because they cause the genetic material to be read incorrectly at certain locations. Genes that are especially critical are those that control the growth and death of cells.

7 Nov 2018

New nuclear medicine tracer could improve diagnosis, treatment of non-small cell lung cancer

Researchers have developed a new nuclear medicine tracer that could improve diagnosis and treatment of non-small cell lung cancer.

7 Nov 2018

Penn and CHOP receive major grant to help curb distracted driving

According to the National Highway Traffic Safety Administration, 3,450 drivers are killed each year from distracted driving. M. Kit Delgado, MD, MS, an assistant professor of Emergency Medicine and Epidemiology in the Perelman School of Medicine at the University of Pennsylvania and an associate fellow at the Center for Injury Research and Prevention at Children's Hospital of Philadelphia, and a team from Penn and CHOP have received a major grant from the Federal Highway Administration, an agency within the United States Department of Transportation, to help curb distracted driving.

7 Nov 2018

New immunotherapy screening prototype helps physicians to effectively target tumors

A new immunotherapy screening prototype developed by University of California, Irvine researchers can quickly create individualized cancer treatments that will allow physicians to effectively target tumors without the side effects of standard cancer drugs.

7 Nov 2018

New synthetic compound based on brain hormone holds promise for cancer treatment

A lab team led by Nobel Prize winner Dr. Andrew Schally at the Miami Veterans Affairs Healthcare System and the University of Miami showed that a synthetic compound based on a brain hormone spurred the growth of cancer cells in Petri dishes but enigmatically had the opposite effect in mice.

6 Nov 2018

Researchers identify pathway to resolve allergic asthma

A group of Brazilian researchers succeeded in preventing allergic asthma from progressing in experimental models by increasing the amount of a protein. This increase, in turn, blocked the CD4+ T lymphocytes responsible for producing a cytokine that triggers a cascade of events resulting in the onset and progression of the disease.

6 Nov 2018

Cancer risk linked to mobile phone radiation in rats but cannot be extrapolated to humans

A new study on laboratory rats has shown that mobile phone radiation exposure is linked to cancers of the brain, heart and the adrenal glands. The rats however were exposed to very high amounts of radiation which is much more than what humans are exposed when they use cell phones.

5 Nov 2018

‘Incredible 2020’ initiative unveiled by ATCC at Neuroscience 2018

Reinforcing its long-established reputation for quality and reliability as the steward for credible biomaterial and standards in the biological sciences, ATCC today announced details of its new initiative, Incredible 2020.

5 Nov 2018

Dietary restriction could help prevent age-related decline in integrity of human gut

Flies eating a Spartan diet are protected from leaky gut and the systemic inflammation associated with it as they age. Conversely, flies on a rich Atkins-like diet are more prone to developing intestinal permeability, a condition linked to a variety of human conditions including inflammatory bowel disease.

5 Nov 2018

US businessman offers $5 million to UTSA College to incubate Alzheimer's challenge

To expand the understanding and explanation of Alzheimer's disease, United States businessman James Truchard has given a $5 million USD gift to The University of Texas at San Antonio College of Sciences to establish the Oskar Fischer Project.

5 Nov 2018

FDA approves LORBRENA for treatment of patients with ALK-positive metastatic NSCLC

Pfizer Inc. today announced that the U.S. Food and Drug Administration has approved LORBRENA, a third-generation anaplastic lymphoma kinase tyrosine kinase inhibitor for patients with ALK-positive metastatic non-small cell lung cancer whose disease has progressed on crizotinib and at least one other ALK inhibitor for metastatic disease; or whose disease has progressed on alectinib or ceritinib as the first ALK inhibitor therapy for metastatic disease.

5 Nov 2018

TGen and City of Hope announce letter of intent to develop new cell therapy manufacturing facility

City of Hope, a world-renowned independent cancer research and treatment center, and its affiliate, Translational Genomics Research Institute, have announced a letter of intent to develop a state-of-the-art cell therapy manufacturing facility in the Phoenix Metropolitan Area, a move that would improve the speed at which stem cell research and cancer treatment is delivered.

5 Nov 2018

VTT, Dyadic to present data highlighting achievements in development of fungal production platform

VTT and Dyadic International, Inc., today announced that VTT scientists will present the excellent results in their collaboration over the past two years at two international conferences: AAPS PharmSci on November 7th in Washington DC and PEGS Europe on November 14th in Lisbon.

5 Nov 2018

Scientists create tiny, biodegradable scaffold to transplant stem cells and deliver drugs

Rutgers scientists have created a tiny, biodegradable scaffold to transplant stem cells and deliver drugs, which may help treat Alzheimer's and Parkinson's diseases, aging brain degeneration, spinal cord injuries and traumatic brain injuries.

5 Nov 2018

Amgen announces presentation of new clinical data showcasing early oncology pipeline at ASH 2018

Amgen today announced that new clinical data will be presented at the 60th American Society of Hematology Annual Meeting & Exposition in San Diego, Dec. 1-4, 2018. Data across an array of malignancies will be featured in 45 abstracts, including nine oral presentations, from the Company’s broad portfolio andearly-stage pipeline.

From AMGEN 5 Nov 2018

Horizon Discovery collaborates with Biocartis to offer reference standards for new Idylla MSI assay

Horizon Discovery Group plc, a global leader in gene editing and gene modulation technologies, today announces that it has developed a set of precisely defined cell line-derived reference standards to support Biocartis’ recently launched Idylla™ microsatellite instability Assay.

From Revvity 5 Nov 2018

Migration affects gut microbiota which in turn affects health find researchers

Human gut contains trillions of helpful and friendly bacteria that makes up the microbiome. These microbes are found to be greatly influential of human conditions including general health to mental health.

4 Nov 2018

B Cell News and Research

Treating pre-cancerous stem cells at early stage could be key to preventing bowel cancer

Study identifies novel missense mutation affecting YARS causes multisystem disease

WPI professor explores how lipids in our bodies and cell membranes affect aging, long-term health

Scientists discover new details about UHRF1 protein

New nuclear medicine tracer could improve diagnosis, treatment of non-small cell lung cancer

Penn and CHOP receive major grant to help curb distracted driving

New immunotherapy screening prototype helps physicians to effectively target tumors

New synthetic compound based on brain hormone holds promise for cancer treatment

Researchers identify pathway to resolve allergic asthma

Cancer risk linked to mobile phone radiation in rats but cannot be extrapolated to humans

‘Incredible 2020’ initiative unveiled by ATCC at Neuroscience 2018

Dietary restriction could help prevent age-related decline in integrity of human gut

US businessman offers $5 million to UTSA College to incubate Alzheimer's challenge

FDA approves LORBRENA for treatment of patients with ALK-positive metastatic NSCLC

TGen and City of Hope announce letter of intent to develop new cell therapy manufacturing facility

VTT, Dyadic to present data highlighting achievements in development of fungal production platform

Scientists create tiny, biodegradable scaffold to transplant stem cells and deliver drugs

Amgen announces presentation of new clinical data showcasing early oncology pipeline at ASH 2018

Horizon Discovery collaborates with Biocartis to offer reference standards for new Idylla MSI assay

Migration affects gut microbiota which in turn affects health find researchers

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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