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Study suggests possible link between body fat and risk of immunotherapy toxicity

Immunotherapy that can be effective against tumors in young, thin mice can be lethal to obese ones, a new study by UC Davis researchers has found.

4 Nov 2014

Researchers develop new test to identify drugs that could work against Lyme disease

Researchers from the Johns Hopkins Bloomberg School of Public Health have developed a test they say will allow them to test thousands of FDA-approved drugs to see if they will work against the bacteria that causes tick-borne Lyme disease.

4 Nov 2014

Gefitinib drug boosts oesophageal cancer patients' survival by up to six months

Patients with a specific type of oesophageal cancer survived longer when they were given the latest lung cancer drug, according to trial results being presented at the National Cancer Research Institute (NCRI) Cancer Conference today (Wednesday).

4 Nov 2014

AstraZeneca, Pharmacyclics partner to evaluate efficacy of IMBRUVICA for solid tumors

AstraZeneca and Pharmacyclics, Inc. today announced that they have entered into a clinical trial collaboration to evaluate a novel combination therapy targeting solid tumors.

4 Nov 2014

NSAIDs protect against colorectal cancer by inducing cell suicide pathways in intestinal stem cells

Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) protect against the development of colorectal cancer by inducing cell suicide pathways in intestinal stem cells that carry a certain mutated and dysfunctional gene, according to a new study led by researchers at the University of Pittsburgh Cancer Institute and the School of Medicine.

4 Nov 2014

Rigel Pharmaceuticals reports net loss of $20.9 million for third quarter of 2014

Rigel Pharmaceuticals, Inc. today reported financial results for the third quarter and nine months ended September 30, 2014.

4 Nov 2014

Smokers are three times more likely to develop chronic back pain than nonsmokers, study finds

If you want to avoid chronic back pain, put out the cigarette. A new Northwestern Medicine study has found that smokers are three times more likely than nonsmokers to develop chronic back pain, and dropping the habit may cut your chances of developing this often debilitating condition.

4 Nov 2014

Inventiva’s IVA337 receives EMA COMP positive opinion on orphan drug designation for SSc treatment

Inventiva, a drug discovery company that focuses on therapeutic approaches involving transcription factors and epigenetic targets, today announces that the Committee for Orphan Medicinal Products (COMP) at the European Medicines Agency (EMA) has given a positive opinion on the designation of IVA337 as an orphan medicinal product.

4 Nov 2014

CVS Health's net revenues increase 9.7% to $35.0B in third quarter 2014

CVS Health Corporation today announced operating results for the three months ended September 30, 2014.

4 Nov 2014

3D brain-like tissue: an interview with Professor David Kaplan, Tufts University

In 2D, neurons tend to form limited connectivity reflective of the 3D complexity in the brain and have more limited cultivation time before reduction in functions.

4 Nov 2014

Triple-S Management announces $50M stock repurchase program, reports consolidated revenues of $567.2M

Triple-S Management Corporation (NYSE: GTS), one of the leading managed care companies in Puerto Rico, today announced consolidated revenues of $567.2 million and consolidated operating income of $8.9 million for the three months ended September 30, 2014.

4 Nov 2014

Anesthetics can cause long-term memory loss, reveal University of Toronto researchers

Researchers at the University of Toronto's Faculty of Medicine have shown why anesthetics can cause long-term memory loss, a discovery that can have serious implications for post-operative patients.

4 Nov 2014

Scientists obtain first structure of the immature form of HIV

Scientists at the European Molecular Biology Laboratory in Heidelberg, Germany and collaborators from Heidelberg University, in the joint Molecular Medicine Partnership Unit, have obtained the first structure of the immature form of HIV at a high enough resolution to pinpoint exactly where each building block sits in the virus.

4 Nov 2014

UC Davis researchers link increased body fat and lethal drug reactions in mice

Immunotherapy that can be effective against tumors in young, thin mice can be lethal to obese ones, a new study by UC Davis researchers has found. The findings, published online today in The Journal of Experimental Medicine, suggest a possible link between body fat and the risk of toxicity from some types of immunotherapy.

3 Nov 2014

New research sheds light on future efforts to eradicate HIV from the body in human patients

Where does HIV hide? Antiretroviral drugs can usually control the virus, but can't completely eliminate it. So any strategy to eradicate HIV from the body has to take into account not only the main group of immune cells the virus targets, called CD4 or helper T cells, but other infected cells as well.

3 Nov 2014

FDA approves Fluzone High-Dose vaccine sBLA to include efficacy data in Prescribing Information

Sanofi Pasteur, the vaccines division of Sanofi, today announced that the U.S. Food and Drug Administration has approved the supplemental biologics license application (sBLA) for Fluzone High-Dose (Influenza Vaccine) to include efficacy data in the Prescribing Information.

3 Nov 2014

NeuroDerm launches initial public offering of 4,500,000 shares

NeuroDerm Ltd., a clinical stage pharmaceutical company developing drugs for central nervous system (CNS) diseases, today announced the launch of its initial public offering of 4,500,000 ordinary shares pursuant to a registration statement on Form F-1 filed with the U.S. Securities and Exchange Commission (SEC).

3 Nov 2014

Epicure project: an interview with Frédéric Cren

Epicure is a project led by Inventiva and Institut Curie that aims to deliver pre-clinical candidates on two novel epigenetic targets that have been selected due to their potential to activate immune responses against cancer cells. In addition one of these two targets has potential in respiratory indications such as asthma or COPD.

3 Nov 2014

Gates Foundation awards US$156 million to support PATH Malaria Vaccine Initiative

In support of a bold quest to rid the world entirely of malaria, the Bill & Melinda Gates Foundation today announced an award of US$156 million to PATH to support the PATH Malaria Vaccine Initiative (MVI) in building new vaccines that will interrupt the cycle of malaria parasite transmission and help realize the "accelerating to zero" agenda. Such vaccines would ensure that parasite reintroduction is prevented by providing what could be called an "immunological bed net."

3 Nov 2014

Eribulin drug could extend life of women with advanced triple negative breast cancer

THE cancer drug eribulin, originally developed from sea sponges, could give women with advanced triple negative breast cancer an average of five extra months of life, according to research presented at the National Cancer Research Institute (NCRI) Cancer Conference in Liverpool today (Monday).

3 Nov 2014

Drugs News and Research

Study suggests possible link between body fat and risk of immunotherapy toxicity

Researchers develop new test to identify drugs that could work against Lyme disease

Gefitinib drug boosts oesophageal cancer patients' survival by up to six months

AstraZeneca, Pharmacyclics partner to evaluate efficacy of IMBRUVICA for solid tumors

NSAIDs protect against colorectal cancer by inducing cell suicide pathways in intestinal stem cells

Rigel Pharmaceuticals reports net loss of $20.9 million for third quarter of 2014

Smokers are three times more likely to develop chronic back pain than nonsmokers, study finds

Inventiva’s IVA337 receives EMA COMP positive opinion on orphan drug designation for SSc treatment

CVS Health's net revenues increase 9.7% to $35.0B in third quarter 2014

3D brain-like tissue: an interview with Professor David Kaplan, Tufts University

Triple-S Management announces $50M stock repurchase program, reports consolidated revenues of $567.2M

Anesthetics can cause long-term memory loss, reveal University of Toronto researchers

Scientists obtain first structure of the immature form of HIV

UC Davis researchers link increased body fat and lethal drug reactions in mice

New research sheds light on future efforts to eradicate HIV from the body in human patients

FDA approves Fluzone High-Dose vaccine sBLA to include efficacy data in Prescribing Information

NeuroDerm launches initial public offering of 4,500,000 shares

Epicure project: an interview with Frédéric Cren

Gates Foundation awards US$156 million to support PATH Malaria Vaccine Initiative

Eribulin drug could extend life of women with advanced triple negative breast cancer

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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